Results 41 to 50 of about 379,827 (391)
Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations.
Humayun Irshad
doaj +1 more source
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis [PDF]
Sds22 defines protein phosphatase 1 location and function at kinetochores and subsequent activity of aurora B in ...
DeLuca, Jennifer G.+5 more
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Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division
The vimentin network displays remarkable plasticity to support basic cellular functions and reorganizes during cell division. Here, we show that in several cell types vimentin filaments redistribute to the cell cortex during mitosis, forming a robust ...
Sofia Duarte+5 more
semanticscholar +1 more source
The transformation of a single fertilised egg into an adult human consisting of tens of trillions of highly diverse cell types is a marvel of biology. The expansion is largely achieved by cell duplication through the process of mitosis.
Charlotte Nugues+2 more
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Chromosome condensation in mitosis and meiosis of rye (Secale cereale L.) [PDF]
Structural investigation and morphometry of meiotic chromosomes by scanning electron microscopy (in comparison to light microscopy) of all stages of condensation of meiosis I + II show remarkable differences during chromosome condensation in mitosis and ...
Herrmann, Reinhold G.+2 more
core +1 more source
Detection of mitotic tumor cells per tissue area is one of the critical markers of breast cancer prognosis. The aim of this paper is to develop a method for the automatic detection of mitotic figures from breast cancer histological slides using a ...
Meriem Sebai+2 more
doaj +1 more source
Quantitative analysis of chromatin compaction in living cells using FLIM-FRET [PDF]
FRET analysis of cell lines expressing fluorescently tagged histones on separate nucleosomes demonstrates that variations in chromosome compaction occur during ...
Angus I. Lamond+52 more
core +4 more sources
Phosphorylation of MCPH1 isoforms during mitosis followed by isoform‐specific degradation by APC/C‐CDH1 [PDF]
Microcephalin‐1 (MCPH1) exists as 2 isoforms that regulate cyclin‐dependent kinase‐1 activation and chromosome condensation during mitosis, with MCPH1 mutations causing primary microcephaly.
Blain, Peter G.+5 more
core +2 more sources
Closed mitosis requires local disassembly of the nuclear envelope
At the end of mitosis, eukaryotic cells must segregate the two copies of their replicated genome into two new nuclear compartments 1 . They do this either by first dismantling and later reassembling the nuclear envelope in an ‘open mitosis’ or by ...
Gautam Dey+5 more
semanticscholar +1 more source
The Biochemistry of Mitosis [PDF]
In this article, we will discuss the biochemistry of mitosis in eukaryotic cells. We will focus on conserved principles that, importantly, are adapted to the biology of the organism. It is vital to bear in mind that the structural requirements for division in a rapidly dividing syncytial Drosophila embryo, for example, are markedly different from those
Jonathon Pines, Samuel Wieser
openaire +3 more sources