Results 41 to 50 of about 383,774 (344)

Automated mitosis detection in histopathology using morphological and multi-channel statistics features

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations.
Humayun Irshad
doaj   +1 more source

Phosphorylation of MCPH1 isoforms during mitosis followed by isoform‐specific degradation by APC/C‐CDH1 [PDF]

open access: yes, 2019
Microcephalin‐1 (MCPH1) exists as 2 isoforms that regulate cyclin‐dependent kinase‐1 activation and chromosome condensation during mitosis, with MCPH1 mutations causing primary microcephaly.
Blain, Peter G.   +5 more
core   +2 more sources

PartMitosis: A Partially Supervised Deep Learning Framework for Mitosis Detection in Breast Cancer Histopathology Images

open access: yesIEEE Access, 2020
Detection of mitotic tumor cells per tissue area is one of the critical markers of breast cancer prognosis. The aim of this paper is to develop a method for the automatic detection of mitotic figures from breast cancer histological slides using a ...
Meriem Sebai   +2 more
doaj   +1 more source

Closed mitosis requires local disassembly of the nuclear envelope

open access: yesbioRxiv, 2019
At the end of mitosis, eukaryotic cells must segregate the two copies of their replicated genome into two new nuclear compartments 1 . They do this either by first dismantling and later reassembling the nuclear envelope in an ‘open mitosis’ or by ...
Gautam Dey   +5 more
semanticscholar   +1 more source

Differential expression of conserved germ line markers and delayed segregation of male and female primordial germ cells in a hermaphrodite, the leech helobdella. [PDF]

open access: yes, 2013
In sexually reproducing animals, primordial germ cells (PGCs) are often set aside early in embryogenesis, a strategy that minimizes the risk of genomic damage associated with replication and mitosis during the cell cycle.
Cho, Sung-Jin   +2 more
core   +2 more sources

Mitosis Detection in Breast Cancer Histology Images via Deep Cascaded Networks

open access: yesAAAI Conference on Artificial Intelligence, 2016
The number of mitoses per tissue area gives an important aggressiveness indication of the invasive breast carcinoma.However, automatic mitosis detection in histology images remains a challenging problem. Traditional methods either employ hand-crafted
Hao Chen   +4 more
semanticscholar   +1 more source

Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation

open access: yesOpen Biology, 2022
Lamin A phosphorylation/de-phosphorylation is an important process during cells division as it allows for nuclear envelope (NE) disassembly at mitotic entry and its re-assembly during mitotic exit.
Florentin Huguet   +4 more
doaj   +1 more source

Mechanisms of Chromosome Congression during Mitosis

open access: yesBiology, 2017
Chromosome congression during prometaphase culminates with the establishment of a metaphase plate, a hallmark of mitosis in metazoans. Classical views resulting from more than 100 years of research on this topic have attempted to explain chromosome ...
H. Maiato   +3 more
semanticscholar   +1 more source

A dynamic mode of mitotic bookmarking by transcription factors. [PDF]

open access: yes, 2016
During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye   +5 more
core   +1 more source

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