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Types of potentials in a mitotic spindle
Biochemistry and Biophysics Reports, 2021 The dynamics of a mitotic spindle is very important to understand if the functioning of mitosis has to be understood and defined very accurately. There are a number of forces involved in such a process.
Yelena Nemchen +2 more
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Mitotic spindle membranes. [PDF]
Mol Biol CellThe mitotic spindle, which uses microtubules (MTs) and MT-based motor proteins to separate sister chromosomes prior to cell division, contains abundant membranes, organelles, and protein assemblies derived from the familiar interphase intracellular membrane network.
Scholey JM.
europepmc +3 more sources
Concentrating on the mitotic spindle [PDF]
Journal of Cell Biology, 2015 In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506107) find that the spindle area is demarcated by a semipermeable organelle barrier. Molecular crowding, which is microtubule independent, causes the enrichment and/or retention of crucial ...
Maddox, Paul S., Ladouceur, Anne-Marie
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The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents [PDF]
, 1988 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
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Nonthermal fluctuations of the mitotic spindle [PDF]
Soft Matter, 2015 Quantitative measurements of fluctuations in the nucleus of mitotic cells can be fully accounted for by a simple model of de-correlated active force fluctuations in a viscoelastic medium dominated by a solution of DNA.
Smith, K. +4 more
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Chromatin Shapes the Mitotic Spindle [PDF]
Journal of End-to-End-testing, 2009 In animal and plant cells, mitotic chromatin locally generates microtubules that self-organize into a mitotic spindle, and its dimensions and bipolar symmetry are essential for accurate chromosome segregation. By immobilizing microscopic chromatin-coated beads on slide surfaces using a microprinting technique, we have examined the effect of chromatin ...
Dinarina, A. +6 more
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Frontiers in Cell and Developmental Biology, 2021 The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu, Susan Boerner
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PLoS ONE, 2020 Recently, human asparagine synthetase has been found to be associated with the mitotic spindle. However, this event cannot be seen in yeast because yeast takes a different cell division process via closed mitosis (there is no nuclear envelope breakdown ...
Chalongrat Noree +1 more
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The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]
, 2009 Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye +15 more
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A cell cycle timer for asymmetric spindle positioning.
PLoS Biology, 2009 The displacement of the mitotic spindle to one side of a cell is important for many cells to divide unequally. While recent progress has begun to unveil some of the molecular mechanisms of mitotic spindle displacement, far less is known about how spindle
Erin K McCarthy Campbell +2 more
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