Results 11 to 20 of about 198,084 (294)
The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents [PDF]
, 1988 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
core +7 more sources
The Drosophila microtubule-associated protein mars stabilizes mitotic spindles by crosslinking microtubules through its N-terminal region. [PDF]
PLoS ONE, 2013 Correct segregation of genetic material relies on proper assembly and maintenance of the mitotic spindle. How the highly dynamic microtubules (MTs) are maintained in stable mitotic spindles is a key question to be answered.
Gang Zhang +3 more
doaj +1 more source
Frontiers in Physiology, 2021 Mitosis proceeds through a defined series of events that is largely conserved, but the amount of time needed for their completion can vary in different cells and organisms.
Mathew Bloomfield +2 more
doaj +1 more source
Concentrating on the mitotic spindle [PDF]
Journal of Cell Biology, 2015 In eukaryotes, the microtubule-based spindle drives chromosome segregation. In this issue, Schweizer et al. (2015; J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506107) find that the spindle area is demarcated by a semipermeable organelle barrier. Molecular crowding, which is microtubule independent, causes the enrichment and/or retention of crucial ...
Maddox, Paul S., Ladouceur, Anne-Marie
openaire +2 more sources
Spatial and Temporal Scaling of Microtubules and Mitotic Spindles
Cells, 2022 During cell division, the mitotic spindle, a macromolecular structure primarily comprised of microtubules, drives chromosome alignment and partitioning between daughter cells.
Benjamin Lacroix, Julien Dumont
doaj +1 more source
Nonthermal fluctuations of the mitotic spindle [PDF]
Soft Matter, 2015 Quantitative measurements of fluctuations in the nucleus of mitotic cells can be fully accounted for by a simple model of de-correlated active force fluctuations in a viscoelastic medium dominated by a solution of DNA.
Smith, K. +4 more
openaire +4 more sources
Frontiers in Cell and Developmental Biology, 2021 The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu, Susan Boerner
doaj +1 more source
Chromatin Shapes the Mitotic Spindle [PDF]
Journal of End-to-End-testing, 2009 In animal and plant cells, mitotic chromatin locally generates microtubules that self-organize into a mitotic spindle, and its dimensions and bipolar symmetry are essential for accurate chromosome segregation. By immobilizing microscopic chromatin-coated beads on slide surfaces using a microprinting technique, we have examined the effect of chromatin ...
Dinarina, A. +6 more
openaire +4 more sources
PLoS ONE, 2020 Recently, human asparagine synthetase has been found to be associated with the mitotic spindle. However, this event cannot be seen in yeast because yeast takes a different cell division process via closed mitosis (there is no nuclear envelope breakdown ...
Chalongrat Noree +1 more
doaj +1 more source
A cell cycle timer for asymmetric spindle positioning.
PLoS Biology, 2009 The displacement of the mitotic spindle to one side of a cell is important for many cells to divide unequally. While recent progress has begun to unveil some of the molecular mechanisms of mitotic spindle displacement, far less is known about how spindle
Erin K McCarthy Campbell +2 more
doaj +1 more source