Results 21 to 30 of about 327,045 (196)
Nonthermal fluctuations of the mitotic spindle [PDF]
Soft Matter, 2015 Quantitative measurements of fluctuations in the nucleus of mitotic cells can be fully accounted for by a simple model of de-correlated active force fluctuations in a viscoelastic medium dominated by a solution of DNA.
Smith, K. +4 more
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Chromatin Shapes the Mitotic Spindle [PDF]
Journal of End-to-End-testing, 2009 In animal and plant cells, mitotic chromatin locally generates microtubules that self-organize into a mitotic spindle, and its dimensions and bipolar symmetry are essential for accurate chromosome segregation. By immobilizing microscopic chromatin-coated beads on slide surfaces using a microprinting technique, we have examined the effect of chromatin ...
Dinarina, A. +6 more
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PLoS ONE, 2020 Recently, human asparagine synthetase has been found to be associated with the mitotic spindle. However, this event cannot be seen in yeast because yeast takes a different cell division process via closed mitosis (there is no nuclear envelope breakdown ...
Chalongrat Noree +1 more
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A cell cycle timer for asymmetric spindle positioning.
PLoS Biology, 2009 The displacement of the mitotic spindle to one side of a cell is important for many cells to divide unequally. While recent progress has begun to unveil some of the molecular mechanisms of mitotic spindle displacement, far less is known about how spindle
Erin K McCarthy Campbell +2 more
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New mitotic regulators released from chromatin
Frontiers in Oncology, 2013 Faithful action of the mitotic spindle segregates duplicated chromosomes into daughter cells. Perturbations of this process result in chromosome mis-segregation, leading to chromosomal instability and cancer development.
Hideki eYokoyama, Oliver eGruss
doaj +1 more source
The mitotic spindle checkpoint [PDF]
Current Biology, 2001 Fantastic progress has been made in understanding the spindle checkpoint, the guardian of balanced chromosome segregation. However, several basic questions and many details remain to be worked out. In the meantime, the use of chimeric fluorescent proteins and ever better imaging technology has enhanced the stunning videos of mitosis made today ...
openaire +2 more sources
Characterization of ring-like F-actin structure as a mechanical partner for spindle positioning in mitosis. [PDF]
PLoS ONE, 2014 Proper spindle positioning and orientation are essential for accurate mitosis which requires dynamic interactions between microtubule and actin filament (F-actin).
Huan Lu +9 more
doaj +1 more source
Fission yeast cells undergo nuclear division in the absence of spindle microtubules. [PDF]
PLoS Biology, 2010 Mitosis in eukaryotic cells employs spindle microtubules to drive accurate chromosome segregation at cell division. Cells lacking spindle microtubules arrest in mitosis due to a spindle checkpoint that delays mitotic progression until all chromosomes ...
Stefania Castagnetti +2 more
doaj +1 more source
PLoS Genetics, 2023 To prevent chromosome mis-segregation, a surveillance mechanism known as the spindle checkpoint delays the cell cycle if kinetochores are not attached to spindle microtubules, allowing the cell additional time to correct improper attachments.
Anne MacKenzie +2 more
doaj +1 more source
Mitotic spindle proteomics in Chinese hamster ovary cells.
PLoS ONE, 2011 Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division.
Mary Kate Bonner +5 more
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