Results 1 to 10 of about 4,204 (164)

Environmental Influence on the Untargeted Foliar Metabolome of Naturally Growing Mitragyna Species in Thailand [PDF]

Plant-Environment Interactions
This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom).
Tushar Andriyas, Nisa Leksungnoen, Chatchai Ngernsaengsaruay, Suwimon Uthairatsamee, Rossarin Tansawat, Pakawat Sirilertpanich   +5 more
doaj   +3 more sources

Discovery of rhynchophylline and mitraphylline in two Thai Mitragyna species and the investigation of their biological activity via opioid gene expression analysis [PDF]

Scientific Reports
Mitragyna speciosa (Ms), M. diversifolia (Md), M. hirsuta (Mh) and M. rotundifolia (Mr) were investigated for phytochemicals by GC-MS and GC-FID, cytotoxicity and genotoxicity testing by MTT and comet assay, and biological activity examination through ...
Runglawan Sudmoon, Tawatchai Tanee, Warin Wonok, Unchaleeporn Ameamsri, Thomas Liehr, Sakda Daduang, Pornnarong Siripiyasing, Arunrat Chaveerach   +7 more
doaj   +2 more sources

Precipitated withdrawal with kratom use following naltrexone administration [PDF]

Mental Health Clinician, 2023
Kratom is an herbal supplement with reports of use for natural pain relief or treatment of opioid withdrawal symptoms. Kratom has metabolites that bind to and agonize mu-opioid receptors similar to opiate medications.
Jarka Courtney PharmD, BCPS, BCPP, Gregoire Kelsey PharmD, BCCCP   +1 more
doaj   +1 more source

Mitragyna speciosa as a Potential Substitute Therapy in Opioid Dependence: A Case Report

Pharmaceutical Sciences and Research, 2022
Preclinical data have consistently suggested the pharmaceutical potential of kratom (Mitragyna speciosa), including as a substitute therapy in opioid dependence.
Karniza Khalid, Jason S.K. Wong, Ruzita Jamaluddin   +2 more
doaj   +1 more source

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Life, 2022
Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation.
Islamudin Ahmad, Wisnu Cahyo Prabowo, Muhammad Arifuddin, Jaka Fadraersada, Niken Indriyanti, Herman Herman, Reza Yuridian Purwoko, Firzan Nainu, Anton Rahmadi, Swandari Paramita, Hadi Kuncoro, Nur Mita, Angga Cipta Narsa, Fajar Prasetya, Arsyik Ibrahim, Laode Rijai, Gemini Alam, Abdul Mun’im, Sukanya Dej-adisai   +18 more
doaj   +1 more source

The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health

G3: Genes, Genomes, Genetics, 2021
Mitragyna speciosaM.
Julia Brose, Kin H Lau, Thu Thuy Thi Dang, John P Hamilton, Lívia do Vale Martins, Britta Hamberger, Bjoern Hamberger, Jiming Jiang, Sarah E O’Connor, C Robin Buell   +9 more
doaj   +1 more source

Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis

Scientific Reports, 2021
Mitragyna speciosa (Korth.) Havil. [MS], or “kratom” in Thai, is the only narcotic species among the four species of Mitragyna in Thailand, which also include Mitragyna diversifolia (Wall. ex G. Don) Havil. [MD], Mitragyna hirsuta Havil.
Chayapol Tungphatthong, Santhosh Kumar J. Urumarudappa, Supita Awachai, Thongchai Sooksawate, Suchada Sukrong   +4 more
doaj   +1 more source

Proximate composition and mineral profile of elephants forages in the Savannah ecological zone of Ghana

Journal of Applied Animal Research, 2023
This study evaluated the proximate and mineral composition of various parts of Balanites aegyptiaca, Mitragyna inermis, Cassia sieberiena, Kigelia africana, Detarium microcarpum, Terminalia laxiflora, Ficus platyphylla and Climber plant (Liana) as feeds ...
Sylvenus Aguree, Samson Abah Abagale, Isaac Sackey   +2 more
doaj   +1 more source

A Chromosome-Scale Genome Assembly of Mitragyna speciosa (Kratom) and the Assessment of Its Genetic Diversity in Thailand

Biology, 2022
Mitragyna speciosa (Kratom) is a tropical narcotic plant native to Southeast Asia with unique pharmacological properties. Here, we report the first chromosome-scale assembly of the M. speciosa genome. We employed PacBio sequencing to obtain a preliminary
Wirulda Pootakham, Thippawan Yoocha, Nukoon Jomchai, Wasitthee Kongkachana, Chaiwat Naktang, Chutima Sonthirod, Srimek Chowpongpang, Panyavut Aumpuchin, Sithichoke Tangphatsornruang   +8 more
doaj   +1 more source

Inhibition of Advanced Glycation End-Products by Tamarindus indica and Mitragyna inermis Extracts and Effects on Human Hepatocyte and Fibroblast Viability

Molecules, 2023
Tamarindus indica and Mitragyna inermis are widely used by herbalists to cure diabetes mellitus. The aim of this study is to investigate the inhibitory potential of aqueous and various organic solvent fractions from both plants and some isolated ...
Relwendé Justin Ouédraogo, Umair Aleem, Lassina Ouattara, Muhammad Nadeem-ul-Haque, Georges Anicet Ouédraogo, Humera Jahan, Farzana Shaheen   +6 more
doaj   +1 more source