MK-801 interferes with the acquisition of amphetamine- and lithium-induced place conditioning [PDF]
, 1997 The place conditioning paradigm was used to assess the ability of the noncompetitive NMDA receptor antagonist, M- 801 to interfere with drug-place associations.
Toth, Jonathan Francis
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Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): The lateral periaqueductal gray (lPAG) is involved in regulating cardiovascular activity. As glutamate is present in this region, the effect of glutamatergic receptors on cardiovascular functions in basic and hypotensive hemorrhagic (Hem ...
Vida Alikhani +2 more
doaj +1 more source
Neurobiology of Disease, 2002 Cerebral ischemia activates ERK and Akt pathways. We studied whether these activations were affected by treatment with the protective growth factor transforming growth factor-α (TGF-α), and whether they were mediated through N-methyl d-aspartate (NMDA ...
Bibiana Friguls +4 more
doaj +1 more source
Ketamine: NMDA receptors and beyond [PDF]
, 2016 Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi +2 more
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Neurobiology of Disease, 1994 Studies on the pathogenesis of human motor neurone disease have suffered from the absence of models of motor neurone degeneration in adult animals. Normally in adult rodents, transection of motor neurone axons results in only a modest degree of neuronal ...
Cynthia Sanner +2 more
doaj +1 more source
SEX-SPECIFIC RESTORATION OF MK-801-INDUCED SENSORIMOTOR GATING DEFICIT BY ENVIRONMENTAL ENRICHMENT [PDF]
Despite ample evidence of N-methyl-D-aspartate (NMDA) receptor dysfunction in schizophrenia, no study has addressed the effects of enriched environment (EE) on sensorimotor gating deficits induced by postnatal NMDA receptor blockade. We evaluated the
ATAPOUR, N +4 more
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Positive allosteric modulation of cannabinoid type-1 receptors: Effects of GAT211 on MK-801-induced behaviors in rats [PDF]
, 2020 Antipsychotics help alleviate the positive symptoms associated with schizophrenia; however, their debilitating side effects spur the search for better treatment options. Acute N-methyl-D-aspartate receptor (NMDAR) blockade with noncompetitive antagonists
McElroy, Dan L
core
MPTP-induced degeneration: interference with glutamatergic toxicity [PDF]
, 1994 Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity.
Lange, Klaus W. +3 more
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NMDA RECEPTORS ARE INVOLVED IN THE ANTIDEPRESSANT-LIKE EFFECTS OF CAPSAICIN FOLLOWING AMPHETAMINE WITHDRAWAL IN MALE MICE [PDF]
, 2016 —Amphetamine withdrawal (AW) is accompanied by diminished pleasure and depression which plays a key role in drug relapse and addictive behaviors. There is no effi- cient treatment for AW-induced depression and underpinning mechanisms were not well ...
Alijanpour, Sakineh. +9 more
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A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e−\u3c/sup\u3e Mediates Aglycemic Neuronal Cell Death [PDF]
, 2015 The astrocyte cystine/glutamate antiporter (system xc−) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred.
He, Yan +5 more
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