Results 91 to 100 of about 16,176 (222)
Fare testislerinde Mk-801’le indüklenen oksidatif strese karşı resveratrolün koruyucu etkisi [PDF]
, 2019 Recently, it has been discovered that the doses of the MK-801 causing schizophrenia also initiate the oxidative stress in the testis. The current study investigated the protective role of the resveratrol against the MK-801 induced oxidative stress in ...
Türkmen, Ruhi +10 more
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Negative modulation of alpha(5) GABA(A) receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion [PDF]
, 2015 Reportedly, negative modulation of alpha(5) GABA(A) receptors may improve cognition in normal and pharmacologically-impaired animals, and such modulation has been proposed as an avenue for treatment of cognitive symptoms in schizophrenia.
Biawat, Poonam +6 more
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Glutamate receptors within the lateral periaqueductal gray (lPAG): Effects on blood pressure and heart rate in basic and hypotensive hemorrhagic rats [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): The lateral periaqueductal gray (lPAG) is involved in regulating cardiovascular activity. As glutamate is present in this region, the effect of glutamatergic receptors on cardiovascular functions in basic and hypotensive hemorrhagic (Hem ...
Vida Alikhani +2 more
doaj +1 more source
Neurobiology of Disease, 2002 Cerebral ischemia activates ERK and Akt pathways. We studied whether these activations were affected by treatment with the protective growth factor transforming growth factor-α (TGF-α), and whether they were mediated through N-methyl d-aspartate (NMDA ...
Bibiana Friguls +4 more
doaj +1 more source
Amnestic effects of NMDA receptor antagonist MK-801 in goldfish.
, 1992 Learning may be mediated by experience-dependent changes in the efficacy of neurotransmission in specific brain pathways. How synaptic efficacy is altered during a learning experience is unknown.
Xu, Xiaojuan
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, 2015 International audienceNoncompetitive N-methyl-D-aspartate receptor antagonists such as phencyclidine and MK-801 are known to impair cognitive function in rodents and humans, and serve as a useful tool to study the cellular basis for pathogenesis of ...
Kemp, Anne +7 more
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(+)-[H-3]MK-801 binding sites in postmortem human brain
, 1990 The pharmacological specificity and the regional distribution of the N-methyl-D-aspartate receptor-associated 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine maleate (MK-801) binding sites in human postmortem brain tissue were determined by
Parker, Joel D. +3 more
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Behavioural effects of inhalation exposure to dizocilpine (MK-801) in mice [PDF]
, 2019 The complex pathophysiology of brain disorders and the difficulty of delivering therapeutic agents to the brain remain major obstacles in the research and development of new therapeutic methods for brain disorders.
Kitamura, Naoya +8 more
core +1 more source
Neurobiology of Disease, 1994 Studies on the pathogenesis of human motor neurone disease have suffered from the absence of models of motor neurone degeneration in adult animals. Normally in adult rodents, transection of motor neurone axons results in only a modest degree of neuronal ...
Cynthia Sanner +2 more
doaj +1 more source
Innenohrprotektive Wirkung von Magnesium und MK-801 unter Hypoxie
, 2003 Einleitung: Die Hypoxie gilt als ein ätiopathogenetischer Faktor bei verschiedenen Erkrankungen des Innenohres. Magnesium (Mg) als Kalzium- und NMDA-Antagonist führt beim Meerschweinchen zu einer signifikanten Verbesserung der Innenohrfunktion unter ...
Haupt, H +4 more
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