Results 101 to 110 of about 16,176 (222)
The NMDAR antagonist MK-801 reduces sleep.
Total daily activity (A) and total sleep (B) for untreated control (white bars, n = 32) and MK-801-fed w1118 flies (black bars, n = 28) in LD and DD conditions. Data are presented as mean ± SEM.
Madoka Mitsuyoshi (747091) +4 more
core +1 more source
Objective: Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema ...
Omay, Bulent +9 more
core +1 more source
Effects of SB-269970 on MK-801-induced glutamate efflux in the prefrontal cortex.
Real-time measurements of glutamate were conducted before and after compound administration. Results are expressed as as mean ± S.E.M of change in glutamate concentrations (N = 5–15 per group).
Leah Aluisio (349456) +7 more
core +1 more source
Comparative genome and proteome analysis of brain tissue from MK-801-treated rats
Symptoms of intoxication with non-competitive N-methyl-D-aspartate (NMDA)-receptor antagonists, closely mimic symptoms in patients with schizophrenia, and therefore [+]-5-methyl-10,11-dihydro-5H-dibenzo-[a,d]-cycloheptene-5,10-iminehydrogen-maleate (MK ...
Paulson, Linda 1971-
core
In this study we investigated the effect of lesioning the noradrenergic systems on the behavioral effects of (5R, 10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo [a, d] cyclohepten-5,10-imine hydrogen maleate-MK-801, in rats.
Hatip-Al-Khatib, I +5 more
core +1 more source
Dystonia induced by combined treatment with L-dopa and MK-801 in parkinsonian monkeys.
We examined whether the N-methyl-D-aspartate antagonist MK-801 (dizocilpine) would reverse parkinsonism or potentiate the effects of L-dopa in primates treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Marsden, CD +10 more
core +1 more source
The macromoleculer oxidation in cerebellum of rat exposed to mk-801 and the protective effect of cape [PDF]
Bu çalışmanın amacı MK-801 ile oluşan nörotoksisitede oksidatif stresin etkisini incelemek, oksidatif stresin önlenmesi ile prognozun düzelebileceğinin gösterilmesidir. MK-801 en nörotoksik NMDA reseptör antagonistlerinden biridir.
Özyurt, Birsen +2 more
core
MK-801 limits neurovascular dysfunction during experimental allergic encephalomyelitis
Increased permeability of the blood-brain barrier (BBB) is a characteristic of the demyelinating disease multiple sclerosis and the animal counterpart experimental allergic encephalomyelitis (EAE).
Christopher Bolton, Carolyn Paul
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