Results 71 to 80 of about 24,407 (221)
Medicinal Research Reviews, EarlyView.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Effect of MK-801 and clozapine on the proteome of cultured human oligodendrocytes
Frontiers in Cellular Neuroscience, 2016 Separate lines of evidence have demonstrated the involvement of NMDA receptor and oligodendrocyte dysfunctions in schizophrenia. Here we have carried out shotgun mass spectrometry proteome analysis of oligodendrocytes treated with the NMDA receptor ...
Juliana Silva Cassoli +8 more
doaj +1 more source
Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice [PDF]
, 2018 Elevated N-methyl-D-aspartate receptor (NMDAR) activity is linked to central sensitization and chronic pain. However, NMDAR antagonists display limited therapeutic potential because of their adverse side effects. Novel approaches targeting the NR2B-PSD95-
Chawla, Aarti +6 more
core +1 more source
Effect of Endodontic Sealers on the Bond Strength of Glass Fibre Posts: A Systematic Review
Australian Endodontic Journal, EarlyView.ABSTRACT This systematic review evaluated the influence of resin‐based, eugenol‐based and bioceramic endodontic sealers on the bond strength of glass fibre posts cemented with resin cements. Searches were conducted in PubMed, Scopus, Web of Science, Cochrane Library, Google Scholar and Embase, including in vitro studies using human or bovine teeth ...
Thiago Bessa Marconato Antunes +7 more
wiley +1 more source
Allergy, EarlyView.Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson +20 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2015 Patients with schizophrenia often manifest deficits in behavioral flexibility. Non-competitive NMDA receptor antagonists such as MK-801 induce schizophrenia-like symptoms in rodents, including cognitive functions.
Jan eSvoboda +5 more
doaj +1 more source
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]
, 2013 NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H +4 more
core +2 more sources
Headache: The Journal of Head and Face Pain, EarlyView.Plain Language Summary Headache is a common health problem, and tobacco products, such as conventional cigarettes and heated tobacco products (HTPs), may be associated with it. Using data from over 23,000 adults in the Japan Society and New Tobacco Internet Survey, we examined the relationships between cigarette and HTP use and self‐reported frequent ...
Masahito Katsuki +12 more
wiley +1 more source
Neurobiology of Disease, 1998 Blockade ofN-methyl-d-aspartate (NMDA) glutamate receptors by MK-801 induces neuronal degeneration in the posterior cingulate/retrosplenial cortex and other corticolimbic regions although damage in the latter has not been adequately characterized.
D.F. Wozniak +7 more
doaj +1 more source
Dopamine D1-like receptor signalling in the hippocampus and amygdala modulates the acquisition of contextual fear conditioning [PDF]
, 2015 RATIONALE: Dopamine D1-like receptor signalling is involved in contextual fear conditioning, but the brain regions involved and its role in other contextual fear memory processes remain unclear.
Bast, Tobias +8 more
core +4 more sources