Results 21 to 30 of about 16,176 (222)
Neurobiology of Disease, 2007 The phencyclidine compound MK-801 can induce psychosis with symptoms which closely resemble those observed in an acute schizophrenic episode. Here we used an in vitro model of psychosis after systemic administration of MK-801.
Colin Kehrer +6 more
doaj +1 more source
Psychiatry and Clinical Psychopharmacology, 2018 INTRODUCTION: Schizophrenia is one of the most severe psychiatric disorders with about 1% prevalence. It has been proved that glutamatergic N-methyl-d-aspartate (NMDA) receptor antagonists such as MK-801 and phencyclidine cause schizophrenia-like ...
Gokhan Unal, Alpay Ates, Feyza Aricioglu
doaj +1 more source
PLoS ONE, 2015 MK-801, also known as dizocilpine, is a noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms.
Wenjuan Yu +5 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2019 MK-801, also known as dizocilpine, is a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. Our previous study showed that brain-derived neurotrophic factor (BDNF) signaling was upregulated in ...
Wenjuan Yu +12 more
doaj +1 more source
Data in Brief, 2019 MK-801, a N-methyl-d-aspartate receptor antagonist, is widely used in animal preclinical experiments to induce memory and learning impairments and schizophrenia-like behavior.
Baiba Svalbe +7 more
doaj +1 more source
Interactions of Cholecystokinin and Glutamatergic Systems in Feeding Behavior of Neonatal Chickens [PDF]
Archives of Razi Institute, 2022 This study aimed to assess the possible feeding behavior alterations by central interactions of cholecystokinin (CCK) and glutamatergic systems in neonatal chickens.
M Jelokhani +3 more
doaj +1 more source
The synergistic effect of treatment with triptolide and MK-801 in the rat neuropathic pain model
Molecular Pain, 2017 Triptolide (T10), an active component of Tripterygium wilfordii Hook F, is reported to have potent anti-inflammatory and analgesic effects. Additionally, MK-801, a noncompetitive N-methyl-D-aspartate receptor antagonist, can reduce glutamate toxicity and
Jian Wang +10 more
doaj +1 more source
, 2013 (A). Plots of inter-spike intervals of a GABA neuron against time, showing that systemic administration of MK-801 gradually changed the distribution of inter-spike intervals from bimodal (two bands) to unimodal (one band), which indicates alterations in ...
Chang-Liang Liu (295048) +3 more
core +1 more source
MK-801 attenuates lesion expansion following acute brain injury in rats: a meta-analysis
Neural Regeneration Research, 2019 Objective: To evaluate the efficacy and safety of MK-801 and its effect on lesion volume in rat models of acute brain injury. Data Sources: Key terms were “stroke”, “brain diseases”, “brain injuries”, “brain hemorrhage, traumatic”, “acute brain injury”, “
Nan-Xing Yi +10 more
doaj +1 more source
MK-801 blocks monoamine transporters expressed in HEK cells
, 1998 (+)-MK-801 is known to be a specific non-competitive antagonist of N-methyl-d-aspartate (NMDA) receptors. However, besides having an anticonvulsant effect, this compound possesses a central sympathomimetic effect and an anxiolytic-like action, raising ...
Shimada, Shoichi +11 more
core +1 more source