Results 41 to 50 of about 16,176 (222)

An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda   +6 more
wiley   +1 more source

MK-801 treatment affects glycolysis in oligodendrocytes more than in astrocytes and neuronal cells: insights for schizophrenia

open access: yesFrontiers in Cellular Neuroscience, 2015
As a multifactorial disease, the underlying causes of schizophrenia require analysis by multiplex methods such as proteomics to allow identification of whole protein networks.
Paul C Guest   +6 more
doaj   +1 more source

Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. [PDF]

open access: yesPLoS ONE, 2011
The role of 5-HT₇ receptor has been demonstrated in various animal models of mood disorders; however its function in cognition remains largely speculative.
Pascal Bonaventure   +7 more
doaj   +1 more source

Effect of Endodontic Sealers on the Bond Strength of Glass Fibre Posts: A Systematic Review

open access: yesAustralian Endodontic Journal, EarlyView.
ABSTRACT This systematic review evaluated the influence of resin‐based, eugenol‐based and bioceramic endodontic sealers on the bond strength of glass fibre posts cemented with resin cements. Searches were conducted in PubMed, Scopus, Web of Science, Cochrane Library, Google Scholar and Embase, including in vitro studies using human or bovine teeth ...
Thiago Bessa Marconato Antunes   +7 more
wiley   +1 more source

Modulation of the levels of NMDA receptor subunit mRNA and the bindings of [3H]MK-801 in rat brain by chronic infusion of subtoxic dose of MK-801

open access: yes, 2018
The effects of continuous infusion of NMDA receptor antagonist MK-801 on the modulation of NMDA receptor subunits NR1, NR2A, NR2B, and NR2C were investigated by using in situ hybridization study. Differential assembly of NMDA receptor subunits determines
오세관, 이희래, 한후재
core   +1 more source

A-582941, cholinergic alpha 7 nicotinic receptor agonist, improved cognitive and negative symptoms of the sub-chronic MK-801 model of schizophrenia in rats

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
OBJECTIVES Nicotinic receptor systems are involved in a wide variety of behavioural functions, including cognitive function, and nicotinic medications, may provide beneficial treatment for cognitive dysfunctions such as schizophrenia.
Gokhan Unal, Feyza Aricioglu
doaj   +1 more source

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

open access: yesAllergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson   +20 more
wiley   +1 more source

Vortioxetine improved negative and cognitive symptoms of schizophrenia in subchronic MK-801 model in rats

open access: yes, 2023
Schizophrenia is a devastating psychiatric disorder with complex symptoms and neurobiology. Serotonergic dysregulation is known to contribute to the pathogenesis of schizophrenia although dopaminergic and glutamatergic systems are thought to have central
Nuh Mehmet Bozkurt   +3 more
core   +1 more source

Socioeconomic Health Disparities in the Treatment of Thyroid Cancer: A Single Institution in Southwestern Ohio

open access: yesHead &Neck, Volume 48, Issue 8, Page 2114-2119, August 2026.
ABSTRACT Background Disparities in thyroid cancer care are driven by demographic and socioeconomic factors such as insurance status, income, and access to specialized care. Methods Retrospective chart review. Demographic and clinical data from 281 adult patients who underwent thyroidectomy or hemithyroidectomy for papillary or follicular thyroid cancer
Breanna Dominguez   +5 more
wiley   +1 more source

Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity

open access: yesFrontiers in Pharmacology, 2018
Attention impairment is a common feature of Major Depressive Disorder (MDD), and MDD-associated cognitive dysfunction may play an important role in determining functional status among this patient population.
Todd M. Hillhouse   +6 more
doaj   +1 more source

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