Results 31 to 40 of about 16,176 (222)
Frontiers in Cellular Neuroscience, 2023 Schizophrenia is a group of severe mental disorders. MiR-25-3p was shown to be involved in various neuropsychiatric diseases and can regulate SIK1 and TWIST1.
Bo Pan +11 more
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Synthesis and Receptor Binding Studies of ( ± )l-Iodo-MK-801
, 1989 The glutamate analogue N -methyl-D-aspartate (NMDA) binds to a subset of glutamate receptors that are coupled to a voltage-sensitive cation channel. This NMDA-linked channel is the likely binding locus of the potent anticonvulsant MK-801.
Young, Anne B. +6 more
core +1 more source
Journal of Experimental Neuroscience, 2015 The present study was designed to investigate the effect of once daily for 7-day (subchronic treatment) dosing of histamine H 3 receptor antagonists, ciproxifan (CPX) (3 mg/kg, i.p.), and clobenpropit (CBP) (15 mg/kg, i.p), including clozapine (CLZ) (3.0
D. Mahmood +5 more
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Decreased MK-801 Binding in Discrete Hippocampal Regions of Prion-Infected Mice
Neurobiology of Disease, 2001 The neurochemical alterations associated with neurodegeneration in prion diseases are not well defined. It is therefore of interest to study the influence of prion infection on messenger molecules and their receptors.
M. Diez +4 more
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Normal MK-801-induced hyperlocomotion.
, 2013 No difference for genotype (black for mutant (n = 8), white for Flox mice (n = 9)) in MK-801-induced locomotor response (two-way repeated measures ANOVA after treatment; p = 0.72).
Gregory R. Rompala (402673) +4 more
core +1 more source
Frontiers in Behavioral Neuroscience, 2021 The neonatal MK-801 model of schizophrenia has been developed based on the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia.
Maria E. Plataki +9 more
doaj +1 more source
Multicontinuum Homogenization for Poroelasticity Model
International Journal for Numerical Methods in Fluids, EarlyView.This work derives a generalized multicontinuum poroelasticity model using the multicontinuum homogenization method to enable accurate coarse‐grid simulations of coupled flow–mechanics processes in highly heterogeneous porous media. Coupled constraint cell problems are formulated, and the corresponding multicontinuum equations are rigorously derived ...
Dmitry Ammosov +2 more
wiley +1 more source
Opposite effects of MK-801 on the expression of food and morphine-induced conditioned place preference in rats [PDF]
, 2006 Behavioural studies have provided strong evidence for common substrates in the rewards of natural and addictive substances, but it is still unclear whether there is a common glutamatergic NMDA receptor mechanism involved in the processing of reward for ...
Zheng, XG +5 more
core
Frontiers in Pharmacology, 2013 Antagonism of N-methyl-D-aspartate (NMDA) receptors by phencyclidine is thought to underlie its ability to induce a schizophrenia-like syndrome in humans, yet evidence indicates it has a broader pharmacological profile.
Wendy K Adams +3 more
doaj +1 more source
Protective effect of resveratrol on kidney and liver histopathology induced by nmda receptor antagonist mk-801 in mice [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 TMK-801 is an antagonist of N-methyl-D-aspartate (NMDA) receptors. Sub-chronic administration of 1 mg / kg dose of MK-801 resulted in schizophrenia-like symptoms and degeneration in the brain of mice.
Murat Sırrı AKOSMAN +2 more
doaj +1 more source