Results 31 to 40 of about 24,407 (221)

Binding of the ligand [3H]MK-801 to the MK-801 binding site of the N-methyl-D-aspartate receptor during experimental encephalopathy from acute liver failure and from acute hyperammonemia in the rabbit [PDF]

open access: yes, 1993
Binding of the ligand [3H]MK-801 to the MK-801 binding site of the N-methyl-D-aspartate (NMDA) receptor population on brain homogenates in rabbits was studied during experimental encephalopathy from acute liver failure and from acute hyperammonemia in ...
Knegt, R.J. (Robert) de   +5 more
core   +2 more sources

Agmatine-attenuated cognitive and social deficits in subchronic MK-801 model of schizophrenia in rats

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
INTRODUCTION: Schizophrenia is one of the most severe psychiatric disorders with about 1% prevalence. It has been proved that glutamatergic N-methyl-d-aspartate (NMDA) receptor antagonists such as MK-801 and phencyclidine cause schizophrenia-like ...
Gokhan Unal, Alpay Ates, Feyza Aricioglu
doaj   +1 more source

Reactive Transformation and Increased BDNF Signaling by Hippocampal Astrocytes in Response to MK-801.

open access: yesPLoS ONE, 2015
MK-801, also known as dizocilpine, is a noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms.
Wenjuan Yu   +5 more
doaj   +1 more source

N-methyl-D-aspartate receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunit delta2 mutant mice. [PDF]

open access: yes, 2005
Classical eyeblink conditioning has been known to depend critically on the cerebellum. Apparently consistent with this, glutamate receptor subunit delta2 null mutant mice, which have serious morphological and functional deficiencies in the cerebellar ...
Fukunaga Satoshi   +6 more
core   +2 more sources

Data on analysis of MK-801 bioavailability in mouse plasma and brain tissue by ultra-performance liquid chromatography-tandem mass spectrometry

open access: yesData in Brief, 2019
MK-801, a N-methyl-d-aspartate receptor antagonist, is widely used in animal preclinical experiments to induce memory and learning impairments and schizophrenia-like behavior.
Baiba Svalbe   +7 more
doaj   +1 more source

Interactions of Cholecystokinin and Glutamatergic Systems in Feeding Behavior of Neonatal Chickens [PDF]

open access: yesArchives of Razi Institute, 2022
This study aimed to assess the possible feeding behavior alterations by central interactions of cholecystokinin (CCK) and glutamatergic systems in neonatal chickens.
M Jelokhani   +3 more
doaj   +1 more source

Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex [PDF]

open access: yes, 2013
El pdf del artículo es la versión post-print.The systemic administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists has been considered as a pharmacological model of schizophrenia.
Adell, Albert   +2 more
core   +2 more sources

Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats

open access: yesFrontiers in Behavioral Neuroscience, 2019
MK-801, also known as dizocilpine, is a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. Our previous study showed that brain-derived neurotrophic factor (BDNF) signaling was upregulated in ...
Wenjuan Yu   +12 more
doaj   +1 more source

Cannabidiol affects MK-801-induced changes in the PPI Learned Response of Capuchin Monkeys (Sapajus spp.) [PDF]

open access: yes, 2017
There are several lines of evidence indicating a possible therapeutic action of cannabidiol (CBD) in schizophrenia treatment. Studies with rodents have demonstrated that CBD reverses MK-801 effects in prepulse inhibition (PPI) disruption, which may ...
Barros, Marília   +4 more
core   +1 more source

The synergistic effect of treatment with triptolide and MK-801 in the rat neuropathic pain model

open access: yesMolecular Pain, 2017
Triptolide (T10), an active component of Tripterygium wilfordii Hook F, is reported to have potent anti-inflammatory and analgesic effects. Additionally, MK-801, a noncompetitive N-methyl-D-aspartate receptor antagonist, can reduce glutamate toxicity and
Jian Wang   +10 more
doaj   +1 more source

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