Matrix metalloproteinase-1 (MMP-1) Promoter polymorphisms are well linked with lower stomach tumor formation in eastern Indian population. [PDF]
PLoS ONE, 2014 Expression of matrix metalloproteinase-1 (MMP-1), an interstitial collagenase, plays a major role in cellular invasion during development of gastric cancer, a leading cause of death worldwide.
Sanjib Dey +5 more
doaj +21 more sources
Food and Agricultural Immunology, 2019 Osteoarthritis (OA) commonly affects the synovial joint and is characterized by degradation of articular cartilage, which is largely mobilized by increased matrix metalloproteinase (MMP) activity.
Shan-Chi Liu +2 more
exaly +2 more sources
Secang wood (Caesalpinia sappan L.) nanoemulgel activity as antiaging through suppressing the MMP-1 expression and the collagen degradation [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2022 Context: Aging is closely related to reactive oxygen species (ROS). ROS increases the collagenase enzyme (MMP-1) levels and collagen degradation that causes skin wrinkling.
Ni Putu Linda Laksmiani +7 more
doaj +1 more source
Journal of Integrative Neuroscience, 2023 Background: The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a variety of physiological and pathological roles in development, remodeling of tissues and diseases, mainly through degradation of various components of the ...
Haijun Zhang +8 more
doaj +1 more source
Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer
Biomedicines, 2022 Locally invasive papillary thyroid carcinoma (PTC) protrudes beyond the thyroid capsule and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are implicated in local invasion and metastasis in PTC.
Irena Ivković +4 more
doaj +1 more source
Effects of Oral and Topical Application of Centella asiatica Extracts on The UVB-Induced Photoaging of Hairless Rats [PDF]
Journal of Pure and Applied Chemistry Research, 2019 Chronic exposure to UVB irradiation can caused premature skin aging (photoaging), as it can trigger the production of ROS and initiate both oxidative stress in cell membrane and affect the molecular pathway.
Yeny Diah Rahmawati +2 more
doaj +1 more source
Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection. [PDF]
, 2017 In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality.
Alland +52 more
core +2 more sources
The effect of micronutrients on postpartum pelvic organ prolapse patients
Majalah Obstetri dan Ginekologi, 2023 HIGHLIGHTS • Serum vitamin D levels were significantly different between POP and in healthy women. • Micronutrient MMP-1 expression is increased in POP patients. ABSTRACT Objective: Pelvic Organ Prolapse (POP) is when pelvic tissues sink into
Rahajeng +2 more
doaj +1 more source
Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]
, 2005 Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N +4 more
core +1 more source
Ciprofloxacin enhances the stimulation of matrix metalloproteinase 3 expression by interleukin-1beta in human tendon-derived cells [PDF]
, 2002 To determine whether the fluoroquinolone antibiotic ciprofloxacin, which can cause tendon pain and rupture in a proportion of treated patients, affects the expression of matrix metalloproteinases (MMPs) in human tendon-derived cells in culture.
Astrom +16 more
core +1 more source