Results 1 to 10 of about 225,487 (143)
Extracellular vesicles delivering TIMP-2 modulate MMP-1, MMP-2, and MMP-9 expression in human lung adenocarcinoma A549 cells [PDF]
Frontiers in PharmacologyBackground/ObjectivesExtracellular vesicles (EVs) carrying therapeutic cargos represent a promising strategy for cancer treatment by enabling the targeted delivery of genetic material directly to cancer cells.
Agnieszka Stawarska +7 more
doaj +2 more sources
Mutiara Medika, 2021 Malignant peripheral nerve sheath tumor (MPNST) is a soft tissue sarcoma, which is difficult to distinguish from other spindle cell sarcomas. MPNST is hostile, with a high recurrence, and tends to metastasize hematogenously, especially to the lungs.
Niniek Hardini +2 more
doaj +1 more source
Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility. [PDF]
, 2018 Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2).
Aguayo, Esteban +11 more
core +16 more sources
MMP-2 and MMP-9 gene polymorphisms and risk of head and neck carcinomas
Romanian Journal of Laboratory Medicine, 2022 Background: Head and neck carcinomas (HNC) account for a majority of ear, nose and throat tumours. They account for 6.3% of all incident malignancies and 6.2 % of all deaths from cancer in Romania in 2020, the fifth most common cancer in this Eastern ...
Schipor Sorina +4 more
doaj +1 more source
Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer
Biomedicines, 2022 Locally invasive papillary thyroid carcinoma (PTC) protrudes beyond the thyroid capsule and invades local structures. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are implicated in local invasion and metastasis in PTC.
Irena Ivković +4 more
doaj +1 more source
Role of MMP-2 and CD147 in kidney fibrosis
Open Life Sciences, 2022 Matrix metalloproteinase-2 (MMP-2) and cluster of differentiation 147 (CD147) both play important roles in the development of kidney fibrosis, and CD147 can induce the production and activation of MMP-2.
Cheng Zhengyuan +4 more
doaj +1 more source
Türk Biyokimya Dergisi, 2022 Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation.
Aksoyer Sezgin Saadet Busra +6 more
doaj +1 more source
A drug cocktail for protecting against ischemia-reperfusion injury
Frontiers in Bioscience-Landmark, 2020 Ischemia followed by reperfusion (I/R) of cardiomyocytes causes release of a large amount of inducible nitric oxide (NO) synthase (iNOS) followed by an increase of asymmetric dimethylarginine (ADMA).
Anna Krzywonos-Zawadzka +3 more
doaj +1 more source
The Effect of IL-8 on Collagen Synthesis in Corneal Fibroblasts
Taiyuan Ligong Daxue xuebao, 2021 IL-8 is highly expressed in tears of keratoconus patients, but its mechanism is still unclear. Abnormal collagen synthesis and degradation are one of the pathogenesis of keratoconus.
Yuning SUN +6 more
doaj +1 more source
Clinical and prognostic features of MMP-2 and VEGF in AEG patients
Open Medicine, 2021 Adenocarcinoma of the esophagogastric junction (AEG) has been increased in recent years and has become a worldwide problem that seriously affects human health.
Zheng Qing-Kang +3 more
doaj +1 more source