Results 281 to 290 of about 246,934 (340)
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MMPs: a novel drug target for schizophrenia
Expert Opinion on Therapeutic Targets, 2015Kanwaljit Chopra, Anurag Kuhad
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Evidence for the Involvement of Matrix-Degrading Metalloproteinases (MMPs) in Atherosclerosis.
Progress in Molecular Biology and Translational Science, 2017 Atherosclerosis leads to blockage of arteries, culminating in myocardial infarction, and stroke. The involvement of matrix-degrading metalloproteinases (MMPs) in atherosclerosis is established and many studies have highlighted the importance of various ...
B. Brown, H. Williams, S. George
semanticscholar +2 more sources
Inhibition of MMPs by alcohols
Dental Materials, 2011 Objectives. While screening the activity of potential inhibitors of matrix metalloproteinases (MMPs), due to the limited water solubility of some of the compounds, they had to be solubilized in ethanol.
Lorenzo Breschi +2 more
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Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma
Virchows Archiv, 2009Merkel cell carcinoma (MCC) is an aggressive cutaneous tumor with poor outcome and increasing incidence. We examined by immunohistochemistry the expression of three novel matrix metalloproteinases (MMPs)-MMP-21, MMP-26, and MMP-28-in 44 primary MCC tumors and six lymph node metastases while MMP-10 served as a positive control. Their mRNA expression was
Sari, Suomela +5 more
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Matrix Metalloproteinase (MMP)-7 Activates MMP-8 But Not MMP-13
Medicinal Chemistry, 2006Matrix Metalloproteinases (MMPs) are a class of zinc-dependent enzymes that degrade extracellular matrix components, particularly collagen. MMPs have been implicated in a diverse list of pathological processes, including cancer and cardiovascular disease.
S, Dozier, G P, Escobar, M L, Lindsey
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Cellular sources of MMP-7, MMP-13 and MMP-28 in ulcerative colitis
Scandinavian Journal of Gastroenterology, 2010Matrix metalloproteinases (MMPs) are considered the predominant proteases in the pathogenesis of mucosal ulcerations associated with inflammatory bowel disease (IBD). Whether the malignancy associated MMP-7 and MMP-13 or the recently cloned MMP-28 convey a certain meaning for intestinal homeostasis and pathogenesis of IBD is currently unknown.
Timo, Rath +5 more
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Genes expression of metalloproteinases (MMP-1, MMP-2, MMP-9, and MMP-12) associated with psoriasis
Russian Journal of Genetics, 2011Using real-time polymerase chain reaction (RT-PCR), we measured mRNA amounts of matrix metalloproteinases (MMPs): MMP-1, MMP-2, MMP-9, and MMP-12 genes in psoriatic lesions and unaffected skin of the same patients. We observed significant (about 15-fold) increase in the expression level of matrix metalloproteinase MMP-1 and MMP-12 genes associated with
N. L. Starodubtseva +4 more
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MT-MMPS as Regulators of Vessel Stability Associated with Angiogenesis [PDF]
Frontiers in Pharmacology, 2011 peer reviewedThe development of vascular system depends on the coordinated activity of a number of distinct families of molecules including growth factors and their receptors, cell adhesion molecules, extracellular matrix (ECM) molecules, and proteolytic
Nor Eddine Sounni, Agnes Noel
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