Results 61 to 70 of about 399 (121)
Papilloma incidence in FoxN1nu/nu mice infected with MmuPV1 DNA.
, 2017 Papilloma incidence in FoxN1nu/nu mice infected with MmuPV1 DNA.
Karl Munger (3215976) +4 more
core +1 more source
HPV8 and MmuPV1 E6 inhibit TGF-β signaling and activity.
, 2017 (A) Proliferation/viability of GFP-control, HPV8 E6, and MmuPV1 E6 expression iHFKs after TGF-β1 (10 ng/ml) treatment over five days as measured by resazurin reduction. P-values (see text) were calculated using Wilcoxon matched-pairs test.
Karl Munger (3215976) +4 more
core +1 more source
The human papillomavirus late life cycle and links to keratinocyte differentiation
Journal of Medical Virology, Volume 96, Issue 2, February 2024.Abstract Regulation of human papillomavirus (HPV) gene expression is tightly linked to differentiation of the keratinocytes the virus infects. HPV late gene expression is confined to the cells in the upper layers of the epithelium where the virus capsid proteins are synthesized.
Anna Kirk, Sheila V. Graham
wiley +1 more source
Functions of Papillomavirus E8^E2 Proteins in Tissue Culture and In Vivo
Viruses, 2022 Papillomaviruses (PV) replicate in undifferentiated keratinocytes at low levels and to high levels in differentiated cells. The restricted replication in undifferentiated cells is mainly due to the expression of the conserved viral E8^E2 repressor ...
Franziska Kuehner, Frank Stubenrauch
doaj +1 more source
Wart Incidence of infected Nude mice.
, 2023 Human papillomaviruses (HPVs) contribute to approximately 5% of all human cancers. Species-specific barriers limit the ability to study HPV pathogenesis in animal models.
Nathalie Lavoie (2293762) +12 more
core +1 more source
A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections. [PDF]
PLoS ONE, 2015 Papillomavirus disease and associated cancers remain a significant health burden in much of the world. The current protective vaccines, Gardasil and Cervarix, are expensive and not readily available to the underprivileged.
Nancy M Cladel +5 more
doaj +1 more source
, 2020 A) RNA sequencing data showing top 20 up-regulated genes by fold change in MmuPV1-induced papillomas in BALBc FoxN1nu/nu mice. Stress keratins (Krt6a, Krt6b, Krt16, Krt17) are highlighted in grey.
Vladimir Majerciak (485025) +9 more
core +1 more source
Viruses, 2017 Preclinical infection model systems are extremely valuable tools to aid in our understanding of Human Papillomavirus (HPV) biology, disease progression, prevention, and treatments.
Aayushi Uberoi, Paul F. Lambert
doaj +1 more source
, 2023 (A) Schematic of a representative HPV E7 protein. Papillomavirus E7 proteins contain conserved regions 1 and 2 (CR1, CR2) and a highly structured C-terminus organized around two zinc binding motifs (CxxC).
Nathalie Lavoie (2293762) +12 more
core +1 more source
Acta Dermato-Venereologica, 2021 Cathelicidins have been reported to inhibit human papillomavirus infection in vitro; however, nothing is known about their activity in vivo. In this study, experimental skin infection with Mus musculus papillomavirus 1 resulted in robust development of ...
Sonja Dorfer +10 more
doaj +1 more source