Results 61 to 70 of about 421 (121)
The human papillomavirus late life cycle and links to keratinocyte differentiation
Journal of Medical Virology, Volume 96, Issue 2, February 2024.Abstract Regulation of human papillomavirus (HPV) gene expression is tightly linked to differentiation of the keratinocytes the virus infects. HPV late gene expression is confined to the cells in the upper layers of the epithelium where the virus capsid proteins are synthesized.
Anna Kirk, Sheila V. Graham
wiley +1 more source
Papilloma incidence in FoxN1nu/nu mice infected with MmuPV1 DNA.
, 2017 Papilloma incidence in FoxN1nu/nu mice infected with MmuPV1 DNA.
Karl Munger (3215976) +4 more
core +1 more source
MmuPV1 E7K81S mutant does not impair viral genome maintenance in basal keratinocytes.
, 2023 (A) Early passage mouse keratinocytes (MKs) isolated from neonates were transfected with dsRed alone or in combination with WT, E7D90A, or E7K81S re-circularized viral genomes.
Nathalie Lavoie (2293762) +12 more
core +1 more source
Functions of Papillomavirus E8^E2 Proteins in Tissue Culture and In Vivo
Viruses, 2022 Papillomaviruses (PV) replicate in undifferentiated keratinocytes at low levels and to high levels in differentiated cells. The restricted replication in undifferentiated cells is mainly due to the expression of the conserved viral E8^E2 repressor ...
Franziska Kuehner, Frank Stubenrauch
doaj +1 more source
A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections. [PDF]
PLoS ONE, 2015 Papillomavirus disease and associated cancers remain a significant health burden in much of the world. The current protective vaccines, Gardasil and Cervarix, are expensive and not readily available to the underprivileged.
Nancy M Cladel +5 more
doaj +1 more source
Viruses, 2017 Preclinical infection model systems are extremely valuable tools to aid in our understanding of Human Papillomavirus (HPV) biology, disease progression, prevention, and treatments.
Aayushi Uberoi, Paul F. Lambert
doaj +1 more source
Wart Incidence of infected Nude mice.
, 2023 Human papillomaviruses (HPVs) contribute to approximately 5% of all human cancers. Species-specific barriers limit the ability to study HPV pathogenesis in animal models.
Nathalie Lavoie (2293762) +12 more
core +1 more source
, 2020 A) RNA sequencing data showing top 20 up-regulated genes by fold change in MmuPV1-induced papillomas in BALBc FoxN1nu/nu mice. Stress keratins (Krt6a, Krt6b, Krt16, Krt17) are highlighted in grey.
Vladimir Majerciak (485025) +9 more
core +1 more source
Acta Dermato-Venereologica, 2021 Cathelicidins have been reported to inhibit human papillomavirus infection in vitro; however, nothing is known about their activity in vivo. In this study, experimental skin infection with Mus musculus papillomavirus 1 resulted in robust development of ...
Sonja Dorfer +10 more
doaj +1 more source
Effects of HPV8 and MmuPV1 E6 on TGF-β nuclear events.
, 2017 (A) Immunoblot analysis of TGF-β signaling components following TGF-β1 treatment in cytoplasmic and nuclear fractions of GFP (C), HPV8 E6 (8E6) or MmuPV1 E6 (ME6) expressing iHFKs.
Karl Munger (3215976) +4 more
core +1 more source