Results 41 to 50 of about 421 (121)
Anal squamous cell carcinomas in KC mice were negative for MmuPV1 infection.
, 2021 (A) No viral signatures were detected in representative anal tumors from KC mice stained via RNAScope ISH with a probe specific to the MmuPV1 E4 region of the genome.
Manabu Nukaya (137154) +7 more
core +1 more source
Viruses, 2021 Papillomaviruses (PVs) are double-stranded DNA tumour viruses that can infect cutaneous and mucosal epidermis. Human papillomavirus (HPV) types have been linked to the causality of cutaneous squamous cell carcinoma (cSCC); however, HPV DNA is not always ...
Allison M. Tschirley +7 more
doaj +1 more source
An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer
mBio, 2020 Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous cell carcinomas (HNSCCs).
Tao Wei +3 more
doaj +1 more source
Deficiency in <i>Ever2</i> does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1. [PDF]
J VirolABSTRACT Epidermodysplasia verruciformis (EV) is a rare genetic skin disorder that is characterized by the development of papillomavirus-induced skin lesions that can progress to squamous cell carcinoma (SCC).
Torres AD +6 more
europepmc +3 more sources
A novel lineage-tracing mouse model for MmuPV1 infection enables in vivo studies in the absence of cytopathic effects [PDF]
, 2021 Abstract Human papillomaviruses (HPVs) are DNA viruses that ubiquitously infect humans and have been associated with hyperproliferative lesions. The recently discovered mouse specific papillomavirus, MmuPV1, provides the opportunity to study papillomavirus infections in vivo in the ...
Vural Yilmaz +2 more
openaire +1 more source
The antiviral effects of a MEK1/2 inhibitor promote tumor regression in a preclinical model of human papillomavirus infection-induced tumorigenesis. [PDF]
Antiviral Res, 2023 Human papillomaviruses (HPVs) are a significant public health concern due to their widespread transmission, morbidity, and oncogenic potential. Despite efficacious vaccines, millions of unvaccinated individuals and those with existing infections will ...
Luna AJ +7 more
europepmc +2 more sources
mBio, 2019 Papillomaviruses exhibit species-specific tropism, thereby limiting understanding and research of several aspects of HPV infection and carcinogenesis.
Megan E. Spurgeon +5 more
doaj +1 more source
Viruses, 2022 The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated the efficacy of topical dihydroartemisinin (DHA)
Laura C. Gunder +12 more
doaj +1 more source
MmuPV1-induced papillomas in UVB-irradiated FVB/NJ mice.
, 2016 (A) Sequence of manipulations to FVB/NJ mice in the MmuPV1-UVB infection model system. Ear sites were scarified and exposed to 108 VGE of MmuPV1 either 24 hours before (FVB+UVB 24h.b.i.+MmuPV) or 24 hours after (FVB+MmuPV+UVB 24h.p.i.) 300mJ/cm2 UVB ...
Satoshi Yoshida (112657) +4 more
core +1 more source
Sequence verification of MmuPV1 E7 in lesions infected with the E7K81S mutant genome.
, 2023 DNA was isolated from FFPE tissue sections and then subjected to PCR for the MmuPV1 E7 gene. PCR products were sent for sequencing to verify presence of the E7K81S mutation. A representative sequencing result is shown. (TIF)
Nathalie Lavoie (2293762) +12 more
core +1 more source