Results 41 to 50 of about 312 (97)

An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer

open access: yesmBio, 2020
Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous cell carcinomas (HNSCCs).
Tao Wei   +3 more
doaj   +1 more source

A novel lineage-tracing mouse model for MmuPV1 infection enables in vivo studies in the absence of cytopathic effects [PDF]

open access: yes, 2021
Abstract Human papillomaviruses (HPVs) are DNA viruses that ubiquitously infect humans and have been associated with hyperproliferative lesions. The recently discovered mouse specific papillomavirus, MmuPV1, provides the opportunity to study papillomavirus infections in vivo in the ...
Vural Yilmaz   +2 more
openaire   +1 more source

A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract

open access: yesmBio, 2019
Papillomaviruses exhibit species-specific tropism, thereby limiting understanding and research of several aspects of HPV infection and carcinogenesis.
Megan E. Spurgeon   +5 more
doaj   +1 more source

Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. [PDF]

open access: yesPLoS ONE, 2012
Despite a growing knowledge about the biological diversity of papillomaviruses (PV), only little is known about non-human PV in general and about PV mice models in particular.
Eric Schulz   +5 more
doaj   +1 more source

Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues

open access: yesViruses, 2021
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth with a newly established ...
Sarah Brendle   +12 more
doaj   +1 more source

The Mouse Papillomavirus Infection Model

open access: yesViruses, 2017
The mouse papillomavirus (MmuPV1) was first reported in 2011 and has since become a powerful research tool. Through collective efforts from different groups, significant progress has been made in the understanding of molecular, virological, and ...
Jiafen Hu   +4 more
doaj   +1 more source

Isolation and quantification of MmuPV1 virions from papillomas v1

open access: yes, 2017
In this section we describe our method of isolation and quantification of MmuPV1 virions from papillomas arising in nude mice that can be serially passaged or used to infect other strains of mice. In our studies we have used both crude virus extracts or purified virus particles.
Aayushi Uberoi, Paul Lambert
openaire   +1 more source

Coinfection with Erethizon dorsatum papillomavirus types 1 and 2 in pigmented papillomatous skin lesions of a North American porcupine in Germany

open access: yesVeterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract We present a case of a coinfection with two papillomaviruses—Erethizon dorsatum papillomavirus types 1 and 2 (EdPV1/2) in a North American porcupine housed in a German zoo. The animal exhibited exophytic black papules on the skin of the face and legs.
Anna Sophie Ramsauer   +4 more
wiley   +1 more source

Microhomology‐mediated repair machinery and its relationship with HPV‐mediated oncogenesis

open access: yesJournal of Medical Virology, Volume 96, Issue 5, May 2024.
Abstract Human Papillomaviruses (HPV) are a diverse family of non‐enveloped dsDNA viruses that infect the skin and mucosal epithelia. Persistent HPV infections can lead to cancer frequently involving integration of the virus into the host genome, leading to sustained oncogene expression and loss of capsid and genome maintenance proteins.
Subhajit Chatterjee, Gabriel J. Starrett
wiley   +1 more source

Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses

open access: yesFrontiers in Microbiology, 2018
Infections with cutaneous papillomaviruses have been linked to cutaneous squamous cell carcinomas that arise in patients who suffer from a rare genetic disorder, epidermodysplasia verruciformis, or those who have experienced long-term, systemic ...
Jordan M. Meyers   +5 more
doaj   +1 more source

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