Results 51 to 60 of about 399 (121)

Mouse Papillomavirus L1 and L2 Are Dispensable for Viral Infection and Persistence at Both Cutaneous and Mucosal Tissues

Viruses, 2021
Papillomavirus L1 and L2, the major and minor capsid proteins, play significant roles in viral assembly, entry, and propagation. In the current study, we investigate the impact of L1 and L2 on viral life cycle and tumor growth with a newly established ...
Sarah Brendle, Jingwei J. Li, Nancy M. Cladel, Debra A. Shearer, Lynn R. Budgeon, Karla K. Balogh, Hannah Atkins, Marina Costa-Fujishima, Paul Lopez, Neil D. Christensen, John Doorbar, Thomas T. Murooka, Jiafen Hu   +12 more
doaj   +1 more source

MmuPV1-induced papillomas in UVB-irradiated FVB/NJ mice.

, 2016
(A) Sequence of manipulations to FVB/NJ mice in the MmuPV1-UVB infection model system. Ear sites were scarified and exposed to 108 VGE of MmuPV1 either 24 hours before (FVB+UVB 24h.b.i.+MmuPV) or 24 hours after (FVB+MmuPV+UVB 24h.p.i.) 300mJ/cm2 UVB ...
Satoshi Yoshida (112657), Henry C. Pitot (461907), Ian H. Frazer (239570), Aayushi Uberoi (2811325), Paul F. Lambert (266676)   +4 more
core   +1 more source

Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. [PDF]

PLoS ONE, 2012
Despite a growing knowledge about the biological diversity of papillomaviruses (PV), only little is known about non-human PV in general and about PV mice models in particular.
Eric Schulz, Marc Gottschling, Rainer G Ulrich, Dania Richter, Eggert Stockfleth, Ingo Nindl   +5 more
doaj   +1 more source

E7^K81S mutant MmuPV1 maintains genome and can generate infectious quasivirus.

, 2023
(A) Unspliced southern blot showing all conditions run on gel image shown in Fig 3. (B) Total RNA was isolated from JB6 mouse epithelial cells 48hrs post-infection with WT MmuPV1, E7D90A, and E7K81S quasivirus preps.
Nathalie Lavoie (2293762), Ella Ward-Shaw (12542830), Karl Munger (3215976), Melanie DePamphilis (15203714), Darya Buehler (15011267), Miranda Grace (155212), James C. Romero-Masters (4112614), Simon Blaine-Sauer (11649097), Denis Lee (280025), Paul F. Lambert (266676), Elizabeth A. White (4512622), Joshua Lei (15203711), Rong Hu (153724)   +12 more
core   +1 more source

BRAF Inhibition and UVB Light Synergistically Promote <i>Mus musculus</i> Papillomavirus 1-Induced Skin Tumorigenesis. [PDF]

Cancers (Basel)
The development of keratinocytic skin tumors, presumably attributable to paradoxical activation of the MAPK pathway, represents a relevant side effect of targeted therapies with BRAF inhibitors (BRAFis).
Dorfer S, Ressler JM, Riebenbauer K, Kancz S, Purkhauser K, Bachmayr V, Cataisson C, Kirnbauer R, Petzelbauer P, Wiesmueller M, Egg M, Hoeller C, Handisurya A.   +12 more
europepmc   +2 more sources

Histopathological analysis of MmuPV1-induced papillomas in UVB –irradiated mice.

, 2016
(A) H&E staining of ear tissue indicating presence of a sessile ear papilloma caused by MmuPV1 in FVB mice following UVB irradiation (left). Presence of koilocytes is indicated (middle). L1-immunofluorescent staining of papillomas (right).
Satoshi Yoshida (112657), Henry C. Pitot (461907), Ian H. Frazer (239570), Aayushi Uberoi (2811325), Paul F. Lambert (266676)   +4 more
core   +1 more source

Coinfection with Erethizon dorsatum papillomavirus types 1 and 2 in pigmented papillomatous skin lesions of a North American porcupine in Germany

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract We present a case of a coinfection with two papillomaviruses—Erethizon dorsatum papillomavirus types 1 and 2 (EdPV1/2) in a North American porcupine housed in a German zoo. The animal exhibited exophytic black papules on the skin of the face and legs.
Anna Sophie Ramsauer, Dimitri Widmer, Eva Ziemmsen, Eva Ludwig, Kurt Tobler   +4 more
wiley   +1 more source

Microhomology‐mediated repair machinery and its relationship with HPV‐mediated oncogenesis

Journal of Medical Virology, Volume 96, Issue 5, May 2024.
Abstract Human Papillomaviruses (HPV) are a diverse family of non‐enveloped dsDNA viruses that infect the skin and mucosal epithelia. Persistent HPV infections can lead to cancer frequently involving integration of the virus into the host genome, leading to sustained oncogene expression and loss of capsid and genome maintenance proteins.
Subhajit Chatterjee, Gabriel J. Starrett
wiley   +1 more source

MmuPV1 E7^K81S mutant does not impair viral genome maintenance in basal keratinocytes.

, 2023
(A) Early passage mouse keratinocytes (MKs) isolated from neonates were transfected with dsRed alone or in combination with WT, E7D90A, or E7K81S re-circularized viral genomes.
Nathalie Lavoie (2293762), Ella Ward-Shaw (12542830), Karl Munger (3215976), Melanie DePamphilis (15203714), Darya Buehler (15011267), Miranda Grace (155212), James C. Romero-Masters (4112614), Simon Blaine-Sauer (11649097), Denis Lee (280025), Paul F. Lambert (266676), Elizabeth A. White (4512622), Joshua Lei (15203711), Rong Hu (153724)   +12 more
core   +1 more source

Depo Medroxyprogesterone (DMPA) Promotes Papillomavirus Infections but Does Not Accelerate Disease Progression in the Anogenital Tract of a Mouse Model

Viruses, 2022
Contraceptives such as Depo-medroxyprogesterone (DMPA) are used by an estimated 34 million women worldwide. DMPA has been associated with increased risk of several viral infections including Herpes simplex virus-2 (HSV-2) and Human immunodeficiency virus
Jiafen Hu, Sarah A. Brendle, Jingwei J. Li, Vonn Walter, Nancy M. Cladel, Timothy Cooper, Debra A. Shearer, Karla K. Balogh, Neil D. Christensen   +8 more
doaj   +1 more source