Results 31 to 40 of about 399 (121)
Efficacy of Topically Administered Dihydroartemisinin in Treating Papillomavirus-Induced Anogenital Dysplasia in Preclinical Mouse Models [PDF]
Viruses, 2022 The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated the efficacy of topical dihydroartemisinin (DHA)
Laura C. Gunder +12 more
doaj +2 more sources
Isolation and quantification of MmuPV1 virions from papillomas v1
, 2017 In this section we describe our method of isolation and quantification of MmuPV1 virions from papillomas arising in nude mice that can be serially passaged or used to infect other strains of mice. In our studies we have used both crude virus extracts or purified virus particles.
Aayushi Uberoi, Paul Lambert
openaire +2 more sources
Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening [PDF]
mBioA substantial percentage of the population remains at risk for cervical cancer due to pre-existing human papillomavirus (HPV) infections, despite prophylactic vaccines. Early diagnosis and treatment are crucial for better disease outcomes.
Hannah M. Atkins +18 more
doaj +2 more sources
Viruses, 2021 Papillomaviruses (PVs) are double-stranded DNA tumour viruses that can infect cutaneous and mucosal epidermis. Human papillomavirus (HPV) types have been linked to the causality of cutaneous squamous cell carcinoma (cSCC); however, HPV DNA is not always ...
Allison M. Tschirley +7 more
doaj +2 more sources
Intraperitoneal delivery of cannabidiol (CBD) and Δ9-tetrahydocannabinol (THC) promotes papillomavirus infections in athymic nude mice [PDF]
Tumour Virus ResearchWe used our mouse papillomavirus (MmuPV1) model to test the hypothesis that two primary psychoactive ingredients of marijuana, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), promote papillomavirus persistence in the oral mucosa of infected mice. We
Sarah A. Brendle +9 more
doaj +2 more sources
The Mouse Papillomavirus Infection Model
Viruses, 2017 The mouse papillomavirus (MmuPV1) was first reported in 2011 and has since become a powerful research tool. Through collective efforts from different groups, significant progress has been made in the understanding of molecular, virological, and ...
Jiafen Hu +4 more
doaj +2 more sources
Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses
Frontiers in Microbiology, 2018 Infections with cutaneous papillomaviruses have been linked to cutaneous squamous cell carcinomas that arise in patients who suffer from a rare genetic disorder, epidermodysplasia verruciformis, or those who have experienced long-term, systemic ...
Jordan M. Meyers +5 more
doaj +2 more sources
mBio, 2021 The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous ...
Tao Wei +6 more
doaj +1 more source
Preclinical Models of Laryngeal Papillomavirus Infection: A Scoping Review
The Laryngoscope, Volume 133, Issue 12, Page 3256-3268, December 2023., 2023 HPV can cause highly morbid laryngeal diseases, including benign communication impairment, and cancer. Preclinical models of these diseases are needed to develop effective treatments. This study summarizes all research studies that describe models of laryngeal HPV infection.
Renee E. King +4 more
wiley +1 more source
Recent advances in cutaneous HPV infection
The Journal of Dermatology, Volume 50, Issue 3, Page 290-298, March 2023., 2023 Abstract More than 200 types of human papillomavirus (HPV) have been reported to date and have been associated with various dermatological diseases. Among dermatological diseases, viral verrucae are the most commonly reported to be associated with HPV.
Akira Shimizu +2 more
wiley +1 more source