Results 31 to 40 of about 312 (97)
Characterization of a Chimeric MmuPV1 Genome with HPV-16E6E7
Proceedings of IMPRS, 2023 Background/Objectives: Papilloma Viruses (PVs) are double-stranded DNA viruses that infect cutaneous and mucosal epithelium. In humans, there are over 100 types of PVs. HPV-16 is a high-risk type that causes ~50% of cervical cancers and ~70% of oropharyngeal cancers by expressing viral oncogenes E6 and E7 in replicating keratinocytes.
Josephine Pyles +3 more
openaire +1 more source
Preclinical Models of Laryngeal Papillomavirus Infection: A Scoping Review
The Laryngoscope, Volume 133, Issue 12, Page 3256-3268, December 2023., 2023 HPV can cause highly morbid laryngeal diseases, including benign communication impairment, and cancer. Preclinical models of these diseases are needed to develop effective treatments. This study summarizes all research studies that describe models of laryngeal HPV infection.
Renee E. King +4 more
wiley +1 more source
mBio, 2021 The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous ...
Tao Wei +6 more
doaj +1 more source
Recent advances in cutaneous HPV infection
The Journal of Dermatology, Volume 50, Issue 3, Page 290-298, March 2023., 2023 Abstract More than 200 types of human papillomavirus (HPV) have been reported to date and have been associated with various dermatological diseases. Among dermatological diseases, viral verrucae are the most commonly reported to be associated with HPV.
Akira Shimizu +2 more
wiley +1 more source
Mus musculus papillomavirus 1 is a key driver of skin cancer development upon immunosuppression
American Journal of Transplantation, Volume 21, Issue 2, Page 525-539, February 2021., 2021 Epidemiological and experimental data implicate cutaneous human papillomavirus infection as co‐factor in the development of cutaneous squamous cell carcinomas (cSCCs), particularly in immunocompromised organ transplant recipients (OTRs). Herein, we established and characterized a skin cancer model, in which Mus musculus papillomavirus 1 (MmuPV1 ...
Sonja Dorfer +9 more
wiley +1 more source
Role of Ultraviolet Radiation in Papillomavirus-Induced Disease. [PDF]
PLoS Pathogens, 2016 Human papillomaviruses are causally associated with 5% of human cancers. The recent discovery of a papillomavirus (MmuPV1) that infects laboratory mice provides unique opportunities to study the life cycle and pathogenesis of papillomaviruses in the ...
Aayushi Uberoi +4 more
doaj +1 more source
Cryo EM Analysis Reveals Inherent Flexibility of Authentic Murine Papillomavirus Capsids
Viruses, 2021 Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic.
Samantha R. Hartmann +6 more
doaj +1 more source
A Novel Model for Papillomavirus-Mediated Anal Disease and Cancer Using the Mouse Papillomavirus
mBio, 2021 Up to 95% of all anal cancers are associated with infection by human papillomavirus (HPV); however, no established preclinical model exists for high-grade anal disease and cancer mediated by a natural papillomavirus infection.
Simon Blaine-Sauer +4 more
doaj +1 more source
Deficiency in <i>Ever2</i> does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1. [PDF]
J VirolABSTRACT Epidermodysplasia verruciformis (EV) is a rare genetic skin disorder that is characterized by the development of papillomavirus-induced skin lesions that can progress to squamous cell carcinoma (SCC).
Torres AD +6 more
europepmc +3 more sources
Viruses, 2021 Papillomaviruses (PVs) are double-stranded DNA tumour viruses that can infect cutaneous and mucosal epidermis. Human papillomavirus (HPV) types have been linked to the causality of cutaneous squamous cell carcinoma (cSCC); however, HPV DNA is not always ...
Allison M. Tschirley +7 more
doaj +1 more source