Results 41 to 50 of about 956,691 (304)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This article focuses on analysing the properties of six varieties of haskap berry (honeyberry) as a valuable raw material for producing health-promoting juices.
Barbara Anna Kowalczyk +2 more
doaj +1 more source
The aroma profiles of two sweet cherry cultivars Kordia and Vanda were investigated during storage at different oxygen and carbon dioxide levels and at a low temperature using solid phase microextraction gas chromatography combined with mass spectrometry
J. Goliáš, J. Létal, O. Veselý
doaj +1 more source
Fractal and Multifractal Analysis of the Rise of Oxygen in Earth's Early Atmosphere
The rise of oxygen in Earth's atmosphere that occurred 2.4 to 2.2 billion years ago is known as the Earth's Great Oxidation, and its impact on the development of life on Earth has been profound. Thereafter, the increase in Earth's oxygen level persisted,
Cuntz, Manfred +2 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
In order to evaluate the influence of modified atmospheres on physicochemical aspects related to the conservation of mango variety vallenato packaging films used for low density polyethylene calibers 2 and 3 mils and three gas mixtures (3% O2-3% CO2-94 ...
Aldo Alexander Fernández Varela +1 more
doaj
Nutritional and sensory evaluation of ready-to-eat salads during shelf life [PDF]
The evolution of the antioxidant and sensory properties of six commercially available ready-to-eat salads, rocket, iceberg lettuce, baby lettuce, lamb’s lettuce, curly endive and radicchio, was studied throughout the shelf life.
PRETI, Raffaella, VINCI, Giuliana
core
A new 147-56 hPa water vapor product from the UARS Microwave Limb Sounder [PDF]
Measurements of H2O in the tropopause region have been obtained by production of a new data set from the Microwave Limb Sounder (MLS) on the Upper Atmosphere Research Satellite (UARS).
Barath +27 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

