Results 121 to 130 of about 3,038,058 (339)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The mechanism of parvalbumin interneurons regulating glutamatergic neurons involvement in stress induced anxiety in the basolateral amygdala of male mice

Scientific Reports
Modern life’s fast-paced and the unexpected conditions contribute to escalating stress levels, often leading to anxiety disorders and posing significant challenges to physical and mental health. In judicial practice, the parties often suffer from anxiety
Xiaorui Su, Xuetong Dong, Chao-Long Lu, Minglong Zhang, Yaping Li, Han Xiao, Jian Wang, Yufei Sun, Bin Cong, Songjun Wang   +9 more
doaj   +1 more source

Correction: Yu et al. The Role of circTmeff-1 in Morphine Addiction Memory of Mice. Cells 2023, 12, 1985

Cells
In the original publication [...]
Hailei Yu, Boyang Wen, Yun Lu, Bing Xie, Feng Yu, Minglong Zhang, Chunling Ma, Bin Cong, Di Wen, Haitao Bi   +9 more
doaj   +1 more source

An Exclusively Skewed Distribution of Pediatric Immune Reconstitution Inflammatory Syndrome Toward the Female Sex Is Associated With Advanced Acquired Immune Deficiency Syndrome

Frontiers in Pediatrics, 2019
In human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) patients with very low CD4 cell counts, there is a temporal relationship between administration of antiretroviral therapy (ART) and an increased inflammatory response ...
Regina Célia de Souza Campos Fernandes, Regina Célia de Souza Campos Fernandes, Regina Célia de Souza Campos Fernandes, Thaís Louvain de Souza, Thaís Louvain de Souza, Thiago da Silva Barcellos, Enrique Medina-Acosta   +6 more
doaj   +1 more source

Comment on "Feshbach-Einstein Condensates" by V. G. Rousseau and P. J. H. Denteneer

, 2010
In a recent paper (Phys. Rev. Lett. 102, 015301 (2009), arXiv:0810.3763) Rousseau and Denteneer claim that an unconventional "super-Mott" (SM) phase is realized by bosons trapped in an optical lattice close to a Feshbach resonance with a molecular state.
Eckholt, María, Roscilde, Tommaso
core   +1 more source

Identification of phytochemical inhibitors of SARS-CoV-2 protease 3CLpro from selected medicinal plants as per molecular docking, bond energies and amino acid binding energies

, 2022
Sami Ullah, Bushra Munir, Abdullah G. Al‐Sehemi, Shabbir Muhammad, Ikram ul Haq, Abida Aziz, Bilal Ahmed, Abdul Ghaffar   +7 more
openalex   +1 more source

Identification of new molecular biomarkers: Proteomics

Sanamed, 2018
The pathogenesis of the tumor is extremely complex and can not be fully explained by the existing methodological approaches. Proteomics is an interdisciplinary science that deals with the study of proteins, carriers of the biological functions of the organism.
openaire   +3 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis

Cellular & Molecular Biology Letters
Abnormal climate change seriously endangers the safety of outdoor work and life, often causing hypothermia-induced coma or death. As the underlying mechanism has not been fully elucidated, a targeted treatment for hypothermia-triggered neuronal injury ...
Song-Jun Wang, Chao-Long Lu, Fu Zhang, Xue-Tong Dong, Xiao-Rui Su, Jing-Jing Sha, Bin Cong, Xia Liu   +7 more
doaj   +1 more source