Results 21 to 30 of about 1,543,233 (247)

Restraint Stress Induced Hyperpermeability and Damage of the Blood-Brain Barrier in the Amygdala of Adult Rats

Frontiers in Molecular Neuroscience, 2019
Intense or prolonged exposure to stress can damage various brain structures, including the amygdala and hippocampus, which are associated with emotional-cognitive functions. Furthermore, this deterioration has been linked to a myriad of neurodegenerative
Guangming Xu, Yingmin Li, Chunling Ma, Chuan Wang, Zhaoling Sun, Yiwen Shen, Li Liu, Shujin Li, Xiaojing Zhang, Bin Cong   +9 more
doaj   +1 more source

Circular RNA as a Potential Biomarker for Forensic Age Prediction

Frontiers in Genetics, 2022
In forensic science, accurate estimation of the age of a victim or suspect can facilitate the investigators to narrow a search and aid in solving a crime.
Junyan Wang, Chunyan Wang, Yangyan Wei, Yanhao Zhao, Can Wang, Chaolong Lu, Jin Feng, Shujin Li, Bin Cong   +8 more
doaj   +1 more source

In-silico guided chemical exploration of KDM4A fragments hits

Clinical Epigenetics, 2023
Background Lysine demethylase enzymes (KDMs) are an emerging class of therapeutic targets, that catalyse the removal of methyl marks from histone lysine residues regulating chromatin structure and gene expression. KDM4A isoform plays an important role in
Jessica Lombino, Rosario Vallone, Maura Cimino, Maria Rita Gulotta, Giada De Simone, Maria Agnese Morando, Raffaele Sabbatella, Simona Di Martino, Mario Fogazza, Federica Sarno, Claudia Coronnello, Maria De Rosa, Chiara Cipollina, Lucia Altucci, Ugo Perricone, Caterina Alfano   +15 more
doaj   +1 more source

Forensic age estimation from human blood using age-related microRNAs and circular RNAs markers

Frontiers in Genetics, 2022
Aging is a complicated process characterized by progressive and extensive changes in physiological homeostasis at the organismal, tissue, and cellular levels.
Junyan Wang, Haixia Zhang, Chunyan Wang, Lihong Fu, Qian Wang, Shujin Li, Bin Cong   +6 more
doaj   +1 more source

Identification of botanicals using molecular biotechnology

Polymers in Medicine, 2023
The available information on the abundance of restorative plants on earth is incomplete, and the data regarding botanicals from various countries differ significantly. The substantial development of the worldwide natural botanical market is attributable to the expanding revenue of global drug companies trading herbal medicines.
Mohd Imran, Tasha Riaz, Haya Majid, Shayan Maqsood   +3 more
openaire   +2 more sources

Innovations in Molecular Identification of Mycobacterium tuberculosis

Journal of Pure and Applied Microbiology, 2022
Tuberculosis (TB) continues to be a significant public health concern on a global scale. Quick and precise identification of Mycobacterium tuberculosis (MTB) in symptomatic patients is pivotal for worldwide TB eradication initiatives.
Mohammad Irfan, Dakshina Bisht
doaj   +1 more source

Butyric acid and valeric acid attenuate stress-induced ferroptosis and depressive-like behaviors by suppressing hippocampal neuroinflammation

Journal of Translational Medicine
Background Depression is closely associated with stress-induced hippocampal damage and dysfunction. Emerging evidence demonstrates that the gut microbiota and its metabolites, acting as probiotics or prebiotics, can modulate brain structure and function ...
Xiaoying Ma, Weibo Shi, Zhen Wang, Shujin Li, Rufei Ma, Weihao Zhu, Lin Wu, Xiaowei Feng, Bin Cong, Yingmin Li   +9 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Disrupted betaine metabolism drives Th17 cell differentiation, mediating methamphetamine-induced depressive behaviors in male mice

Journal of Neuroinflammation
Methamphetamine (METH) abuse, a global public health concern, is closely linked to neuropsychiatric disorders such as depression. Although the central nervous system (CNS) damage induced by METH is well documented, the role of peripheral immune ...
Rongji Hui, Jiabao Xu, Hongchen Ma, Tao Feng, Congcong Hou, Xintao Wang, Mingyang Jin, Feng Yu, Yan Shi, Bing Xie, Ludi Zhang, Bin Cong, Chunling Ma, Di Wen   +13 more
doaj   +1 more source

Molecular Identification of Campylobacter concisus [PDF]

Journal of Clinical Microbiology, 2001
ABSTRACT A 1.6-kb DNA fragment isolated from a Campylobacter concisus genomic library gave C. concisus -specific restriction fragment length patterns when it was used as a probe in hybridization studies.
M I, Matsheka, A J, Lastovica, B G, Elisha   +2 more
openaire   +2 more sources