Results 51 to 60 of about 3,038,058 (339)

The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride

Frontiers in Molecular Neuroscience, 2022
Methamphetamine (METH) abuse causes irreversible damage to the central nervous system and leads to psychiatric symptoms including depression. Notably, METH-induced hyperthermia is a crucial factor in the development of these symptoms, as it aggravates ...
Xintao Wang, Xintao Wang, Xintao Wang, Bonan Tong, Bonan Tong, Bonan Tong, Rongji Hui, Rongji Hui, Rongji Hui, Congcong Hou, Congcong Hou, Congcong Hou, Zilu Zhang, Ludi Zhang, Ludi Zhang, Ludi Zhang, Bing Xie, Bing Xie, Bing Xie, Zhiyu Ni, Bin Cong, Bin Cong, Bin Cong, Chunling Ma, Chunling Ma, Chunling Ma, Di Wen, Di Wen, Di Wen   +28 more
doaj   +1 more source

Resistance to bleomycin increases the chronological life of cells [PDF]

, 2019
The identification of genes involved in chronological aging could have a potential utility as molecular markers in the chemotherapy treatment of cancer.
Burgos-Molina, Antonio Manuel, Gil-Carmona, Luisa, Mercado-Sáenz, Silvia, Ruiz-Gomez, Miguel Jose   +3 more
core  

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]

, 2011
This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Metabolomic Profiles of a Midge (Procladius villosimanus, Kieffer) Are Associated with Sediment Contamination in Urban Wetlands

Metabolites, 2017
Metabolomic techniques are powerful tools for investigating organism-environment interactions. Metabolite profiles have the potential to identify exposure or toxicity before populations are disrupted and can provide useful information for environmental ...
Katherine J. Jeppe, Konstantinos A. Kouremenos, Kallie R. Townsend, Daniel F. MacMahon, David Sharley, Dedreia L. Tull, Ary A. Hoffmann, Vincent Pettigrove, Sara M. Long   +8 more
doaj   +1 more source

Molecular Identification of Pseudouridine-metabolizing Enzymes [PDF]

Journal of Biological Chemistry, 2008
Pseudouridine, a non-classical nucleoside present in human urine as a degradation product of RNAs, is one of the few molecules that has a glycosidic C-C bond. Through a data base mining approach involving transcriptomic data, we have molecularly identified two enzymes that are involved in the metabolism of pseudouridine in uropathogenic Escherichia ...
Alice, Preumont, Karim, Snoussi, Vincent, Stroobant, Jean-François, Collet, Emile, Van Schaftingen   +4 more
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

Frontiers in Molecular Neuroscience
Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly abundant in the
Chuan Wang, Qian Wang, Guangming Xu, Guangming Xu, Zhaoling Sun, Dong Zhang, Dong Zhang, Chunling Ma, Yingmin Li, Di Wen, Xiaojing Zhang, Bin Cong, Bin Cong   +12 more
doaj   +1 more source

Identification of the Molecule-Metal Bonding Geometries of Molecular Nanowires

, 2011
Molecular nanowires in which a single molecule bonds chemically to two metal electrodes and forms a stable electrically conducting bridge between them have been studied intensively for more than a decade.
Demir, Firuz, Kirczenow, George
core   +1 more source