Results 11 to 20 of about 336,872 (260)

Prospects for single-molecule electrostatic detection in molecular motor gliding motility assays

open access: yesNew Journal of Physics, 2021
Molecular motor gliding motility assays based on myosin/actin or kinesin/microtubules are of interest for nanotechnology applications ranging from cargo-trafficking in lab-on-a-chip devices to novel biocomputation strategies.
M Sanchez Miranda   +5 more
doaj   +1 more source

Biochemical and Biophysical Characterization of the dsDNA Packaging Motor from the Lactococcus lactis Bacteriophage Asccphi28

open access: yesViruses, 2020
Double-stranded DNA viruses package their genomes into pre-assembled protein procapsids. This process is driven by macromolecular motors that transiently assemble at a unique vertex of the procapsid and utilize homomeric ring ATPases to couple genome ...
Emilio Reyes-Aldrete   +9 more
doaj   +1 more source

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

open access: yeseLife, 2014
Microtubule-based transport by the kinesin motors, powered by ATP hydrolysis, is essential for a wide range of vital processes in eukaryotes. We obtained insight into this process by developing atomic models for no-nucleotide and ATP states of the ...
Zhiguo Shang   +5 more
doaj   +1 more source

Rotary mechanism of V/A-ATPases—how is ATP hydrolysis converted into a mechanical step rotation in rotary ATPases?

open access: yesFrontiers in Molecular Biosciences, 2023
V/A-ATPase is a rotary molecular motor protein that produces ATP through the rotation of its central rotor. The soluble part of this protein, the V1 domain, rotates upon ATP hydrolysis.
Ken Yokoyama
doaj   +1 more source

Multiscale Modeling of Skeletal Muscle Active Contraction in Relation to Mechanochemical Coupling of Molecular Motors

open access: yesMicromachines, 2015
In this work, a mathematical model was developed to relate the mechanochemical characterizations of molecular motors with the macroscopic manifestation of muscle contraction.
Jiangcheng Chen   +4 more
doaj   +1 more source

Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors

open access: yeseLife, 2018
The light chains (KLCs) of the heterotetrameric microtubule motor kinesin-1, that bind to cargo adaptor proteins and regulate its activity, have a capacity to recognize short peptides via their tetratricopeptide repeat domains (KLCTPR). Here, using X-ray
Stefano Pernigo   +9 more
doaj   +1 more source

Langevin approach to the Porto system

open access: yesEntropy, 2004
: M. Porto (Phys. Rev. E 63 (2001) 030102) suggested a system consisting of Coulomb interacting particles, forming a linear track and a rotor, and working as a molecular motor. Newton equations with damping for the rotor coordinate on the track x, with a
Vladislav Cápek, Jirí Bok
doaj   +1 more source

Traffic of Molecular Motors [PDF]

open access: yes, 2007
10 pages, latex, uses Springer styles (included), to appear in the Proceedings of "Traffic and Granular Flow 2005"
Klumpp, S., Müller, M., Lipowsky, R.
openaire   +3 more sources

The force exerted by a molecular motor [PDF]

open access: yesProceedings of the National Academy of Sciences, 1999
The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An elementary “barometric” relation for the driving force is introduced that ( i
Fisher, Michael E.   +1 more
openaire   +3 more sources

Cellular Motors for Molecular Manufacturing [PDF]

open access: yesThe Anatomical Record, 2007
AbstractCells are composed of macromolecular structures of various sizes that act individually or collectively to maintain their viability and perform their function within the organism. This review focuses on one structure, the microtubule, and one of the motor proteins that move along it, conventional kinesin (kinesin 1).
Dinu, C.   +3 more
openaire   +3 more sources

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