Results 191 to 200 of about 4,509,513 (302)

Molecular motor-driven reversible liquid-liquid phase separation of supramolecular assemblies. [PDF]

Nat Commun
Xu F, Ovalle M, Fu Y, Stuart MAC, Feringa BL.   +4 more
europepmc   +1 more source

Author Correction: Towards the engineering of a photon-only two-stroke rotary molecular motor. [PDF]

Nat Commun, 2022
Filatov Gulak M, Paolino M, Pierron R, Cappelli A, Giorgi G, Léonard J, Huix-Rotllant M, Ferré N, Yang X, Kaliakin D, Blanco-González A, Olivucci M.   +11 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Competing Photoisomerization and Excited-State Intramolecular Proton Transfer in a Visible-Light-Driven Salicylidene Schiff Base Functionalized Molecular Motor: Insights from Ultrafast Nonadiabatic Dynamics Simulations. [PDF]

Int J Mol Sci
Pang X, Yan Y, Cui X, Zhang N.
europepmc   +1 more source

Binding partners regulate unfolding of myosin VI to activate the molecular motor. [PDF]

Biochem J, 2022
Dos Santos Á, Fili N, Hari-Gupta Y, Gough RE, Wang L, Martin-Fernandez M, Aaron J, Wait E, Chew TL, Toseland CP.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Catalysis-Driven Dual Molecular Motor. [PDF]

J Am Chem Soc
Wang PL, Olivieri E, Borsley S, Whitehead GFS, Hasija A, Leigh DA.   +5 more
europepmc   +1 more source

Solving Exact Cover Instances with Molecular-Motor-Powered Network-Based Biocomputation. [PDF]

ACS Nanosci Au, 2022
Surendiran P, Meinecke CR, Salhotra A, Heldt G, Zhu J, Månsson A, Diez S, Reuter D, Kugler H, Linke H, Korten T.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Achieving one-step molecular photogearing in a minimal light-driven molecular motor. [PDF]

Chem Sci
Arpa EM, Durbeej B.
europepmc   +1 more source