Results 31 to 40 of about 5,860,920 (296)
Multiscale molecular dynamics simulations of rotary motor proteins [PDF]
Protein functions require specific structures frequently coupled with conformational changes. The scale of the structural dynamics of proteins spans from the atomic to the molecular level. Theoretically, all-atom molecular dynamics (MD) simulation is a powerful tool to investigate protein dynamics because the MD simulation is capable of capturing ...
Toru Ekimoto, Mitsunori Ikeguchi
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Amyotrophic lateral sclerosis is the most common adult-onset neurodegenerative disease affecting motor neurons. Its defining feature is progressive loss of motor neuron function in the cortex, brainstem, and spinal cord, leading to paralysis and death ...
Rita F Marques, Kent E Duncan
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An autonomous molecular transport system using DNAs and motor proteins in molecular communication [PDF]
This paper describes a molecular transport system in molecular communication that uses the machinery in living cells. The molecular transport system requires: 1) loading of the specified cargo molecules at a loading site (at a sender); 2) transport of the loaded cargoes to an unloading site (to a receiver); and 3) unloading of the transported cargoes ...
S. Hiyama +4 more
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Motor proteins at the mitochondria-cytoskeleton interface. [PDF]
Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways.
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MAPping out distribution routes for kinesin couriers [PDF]
In the crowded environment of eukaryotic cells, diffusion is an inefficient distribution mechanism for cellular components. Long-distance active transport is required and is performed by molecular motors including kinesins.
Moores, Carolyn A. +5 more
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Molecular motors in nanobiotechnology: Protein and DNA based molecular motors: A review
Molecular motor can be defined as the collection of a separate number of molecular features (that is, a supramolecular structure) which has been developed to carry out a function through the mechanical movements of its components, which occurs when it is appropriately stimulated externally. Therefore, molecular motors include a part with a motor, which
Yathrib Ajaj +8 more
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Pathological alterations of the Golgi apparatus, such as its fragmentation represent an early pre-clinical feature of many neurodegenerative diseases and have been widely studied in the motor neuron disease amyotrophic lateral sclerosis (ALS).
Georg eHaase, Catherine eRabouille
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Editorial to the Special Issue “Molecular Motors: From Single Molecules to Cooperative and Regulatory Mechanisms In Vivo” [PDF]
The Molecular motors or motor proteins are able to generate force and do mechanical work that is used to displace a load or produce relative movements between molecules or macromolecular assembles [...
Capitanio, Marco +3 more
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Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution
An important question in cell biology is how cytoskeletal proteins evolved and drove the development of novel structures and functions. Here we address the origin of SPIRE actin nucleators.
Martin Kollmar +14 more
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Dynamics of molecular motors in reversible burnt-bridge models
Dynamic properties of molecular motors whose motion is powered by interactions with specific lattice bonds are studied theoretically with the help of discrete-state stochastic "burnt-bridge" models.
M.N. Artyomov +2 more
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