Results 31 to 40 of about 5,860,920 (296)

Multiscale molecular dynamics simulations of rotary motor proteins [PDF]

open access: yesBiophysical Reviews, 2017
Protein functions require specific structures frequently coupled with conformational changes. The scale of the structural dynamics of proteins spans from the atomic to the molecular level. Theoretically, all-atom molecular dynamics (MD) simulation is a powerful tool to investigate protein dynamics because the MD simulation is capable of capturing ...
Toru Ekimoto, Mitsunori Ikeguchi
openaire   +2 more sources

SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology

open access: yesNeural Regeneration Research, 2022
Amyotrophic lateral sclerosis is the most common adult-onset neurodegenerative disease affecting motor neurons. Its defining feature is progressive loss of motor neuron function in the cortex, brainstem, and spinal cord, leading to paralysis and death ...
Rita F Marques, Kent E Duncan
doaj   +1 more source

An autonomous molecular transport system using DNAs and motor proteins in molecular communication [PDF]

open access: yes2007 2nd Bio-Inspired Models of Network, Information and Computing Systems, 2007
This paper describes a molecular transport system in molecular communication that uses the machinery in living cells. The molecular transport system requires: 1) loading of the specified cargo molecules at a loading site (at a sender); 2) transport of the loaded cargoes to an unloading site (to a receiver); and 3) unloading of the transported cargoes ...
S. Hiyama   +4 more
openaire   +1 more source

Motor proteins at the mitochondria-cytoskeleton interface. [PDF]

open access: yes, 2021
Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways.

core   +2 more sources

MAPping out distribution routes for kinesin couriers [PDF]

open access: yes, 2013
In the crowded environment of eukaryotic cells, diffusion is an inefficient distribution mechanism for cellular components. Long-distance active transport is required and is performed by molecular motors including kinesins.
Moores, Carolyn A.   +5 more
core   +1 more source

Molecular motors in nanobiotechnology: Protein and DNA based molecular motors: A review

open access: yesResults in Chemistry
Molecular motor can be defined as the collection of a separate number of molecular features (that is, a supramolecular structure) which has been developed to carry out a function through the mechanical movements of its components, which occurs when it is appropriately stimulated externally. Therefore, molecular motors include a part with a motor, which
Yathrib Ajaj   +8 more
openaire   +2 more sources

Golgi fragmentation in ALS motor neurons. New mechanisms targeting microtubules, tethers and transport vesicles.

open access: yesFrontiers in Neuroscience, 2015
Pathological alterations of the Golgi apparatus, such as its fragmentation represent an early pre-clinical feature of many neurodegenerative diseases and have been widely studied in the motor neuron disease amyotrophic lateral sclerosis (ALS).
Georg eHaase, Catherine eRabouille
doaj   +1 more source

Editorial to the Special Issue “Molecular Motors: From Single Molecules to Cooperative and Regulatory Mechanisms In Vivo” [PDF]

open access: yes, 2022
The Molecular motors or motor proteins are able to generate force and do mechanical work that is used to displace a load or produce relative movements between molecules or macromolecular assembles [...
Capitanio, Marco   +3 more
core   +1 more source

Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution

open access: yesCommunications Biology
An important question in cell biology is how cytoskeletal proteins evolved and drove the development of novel structures and functions. Here we address the origin of SPIRE actin nucleators.
Martin Kollmar   +14 more
doaj   +1 more source

Dynamics of molecular motors in reversible burnt-bridge models

open access: yesCondensed Matter Physics, 2010
Dynamic properties of molecular motors whose motion is powered by interactions with specific lattice bonds are studied theoretically with the help of discrete-state stochastic "burnt-bridge" models.
M.N. Artyomov   +2 more
doaj   +1 more source

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