Results 31 to 40 of about 7,543,664 (335)

Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry [PDF]

open access: yes, 2013
Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other.
Li, Jianwei,   +2 more
core   +7 more sources

Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes

open access: yesNature Communications, 2019
Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song   +3 more
doaj   +1 more source

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins. [PDF]

open access: yes, 2019
Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication.
Du Bois, J   +4 more
core   +2 more sources

Differential regulation of the Epr3 receptor coordinates membrane-restricted rhizobial colonization of root nodule primordia

open access: yesNature Communications, 2017
TheLotus japonicus LysM receptor kinase EPR3 perceives rhizobial exopolysaccharides to initiate infection of the root epidermis. Here the authors show that EPR3 also mediates infection thread progression in the root cortex and show that key transcription
Yasuyuki Kawaharada   +10 more
doaj   +1 more source

Molecular recognition on acoustic wave devices [PDF]

open access: yes, 1993
Microporous thin films composed of a molecular coupling layer, zeolite crystals, and a porous silica overlayer, were formed on the gold electrodes of quartz crystal microbalances (QCMs).
Bein, Thomas, Yan, Yongan
core   +1 more source

Gold-catalyzed stereoselective cycloisomerization of allenoic acids for two types of common natural γ-butyrolactones

open access: yesNature Communications, 2018
Gamma-butyrolactones are widespread in Nature, however direct catalytic methods to access them are limited. Here, the authors report a gold-catalyzed cycloisomerization of allenoic acids to acces γ-butyrolactones and apply it to the asymmetric synthesis ...
Jing Zhou, Chunling Fu, Shengming Ma
doaj   +1 more source

Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance

open access: yesDiagnostics, 2023
Since its discovery, polymerase chain reaction (PCR) has emerged as an important technology for the diagnosis and identification of infectious diseases.
Emmanuel George Kifaro   +8 more
doaj   +1 more source

Reinforced molecular recognition as an alternative to rigid receptors [PDF]

open access: yes, 2006
In theory, a perfectly rigid receptor will probably be an unbeatable binder. However, rigidity may not be easy to achieve in practice and it is certainly not Nature’s method to realise high affinity. In many proteins binding affinity is increased through
Otto, Sijbren,
core   +1 more source

Bioinspired tetraamino-bisthiourea chiral macrocycles in catalyzing decarboxylative Mannich reactions

open access: yesBeilstein Journal of Organic Chemistry, 2022
A series of tetraamino-bisthiourea chiral macrocycles containing two diarylthiourea and two chiral diamine units were synthesized by a fragment-coupling approach in high yields.
Hao Guo   +3 more
doaj   +1 more source

Photoredox cooperative N-heterocyclic carbene/palladium-catalysed alkylacylation of alkenes

open access: yesNature Communications, 2022
Three-component carboacylation of simple alkenes often requires directing groups and strained substrates. Here, the authors report a photoredox N-heteroyclic carbene/Pd-catalysed alkylacylation of alkenes with aldehydes and unactivated alkyl halides ...
You-Feng Han   +5 more
doaj   +1 more source

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