Results 31 to 40 of about 6,845,981 (383)
Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]
, 2002 Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Casey, Lorraine A. +4 more
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Nature Communications, 2017 TheLotus japonicus LysM receptor kinase EPR3 perceives rhizobial exopolysaccharides to initiate infection of the root epidermis. Here the authors show that EPR3 also mediates infection thread progression in the root cortex and show that key transcription
Yasuyuki Kawaharada +10 more
doaj +1 more source
Reinforced molecular recognition as an alternative to rigid receptors [PDF]
, 2006 In theory, a perfectly rigid receptor will probably be an unbeatable binder. However, rigidity may not be easy to achieve in practice and it is certainly not Nature’s method to realise high affinity. In many proteins binding affinity is increased through
Otto, Sijbren,
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Nature Communications, 2018 Gamma-butyrolactones are widespread in Nature, however direct catalytic methods to access them are limited. Here, the authors report a gold-catalyzed cycloisomerization of allenoic acids to acces γ-butyrolactones and apply it to the asymmetric synthesis ...
Jing Zhou, Chunling Fu, Shengming Ma
doaj +1 more source
Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance
Diagnostics, 2023 Since its discovery, polymerase chain reaction (PCR) has emerged as an important technology for the diagnosis and identification of infectious diseases.
Emmanuel George Kifaro +8 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2022 A series of tetraamino-bisthiourea chiral macrocycles containing two diarylthiourea and two chiral diamine units were synthesized by a fragment-coupling approach in high yields.
Hao Guo +3 more
doaj +1 more source
Photoredox cooperative N-heterocyclic carbene/palladium-catalysed alkylacylation of alkenes
Nature Communications, 2022 Three-component carboacylation of simple alkenes often requires directing groups and strained substrates. Here, the authors report a photoredox N-heteroyclic carbene/Pd-catalysed alkylacylation of alkenes with aldehydes and unactivated alkyl halides ...
You-Feng Han +5 more
doaj +1 more source
A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era. Selecting cases, matching clinical benefit. A position paper from the Italian Group of Haematopathology (G.I.E.) [PDF]
, 2019 An accurate diagnosis of clinically distinct subgroups of aggressive mature B cell lymphomas is crucial for the choice of proper treatment. Presently, precise recognition of these disorders relies on the combination of morphological, immunophenotypical ...
Agostinelli, C. +17 more
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Policies and Procedures for the Termination of War Contracts [PDF]
, 1944 The concept of recognition and biofunctionality has attracted increasing interest in the fields of chemistry and material sciences. Advances in the field of nanotechnology for the synthesis of desired metal oxide nanostructures have provided a solid ...
Kimleang Khun +2 more
core +3 more sources
Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools. [PDF]
, 2016 This review discusses the use of molecular modeling tools, together with existing experimental findings, to provide a complete atomic-level description of enzyme dynamics and function.
Chang, Chia-En A +3 more
core +2 more sources