Results 31 to 40 of about 1,544,923 (334)

Microparticles as Viral RNA Carriers from Stool for Stable and Sensitive Surveillance

open access: yesDiagnostics, 2023
Since its discovery, polymerase chain reaction (PCR) has emerged as an important technology for the diagnosis and identification of infectious diseases.
Emmanuel George Kifaro   +8 more
doaj   +1 more source

Molecular recognition on acoustic wave devices [PDF]

open access: yes, 1993
Microporous thin films composed of a molecular coupling layer, zeolite crystals, and a porous silica overlayer, were formed on the gold electrodes of quartz crystal microbalances (QCMs).
Bein, Thomas, Yan, Yongan
core   +1 more source

Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation

open access: yesNature Communications, 2016
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang   +5 more
doaj   +1 more source

MolScribe: Robust Molecular Structure Recognition with Image-To-Graph Generation [PDF]

open access: yes, 2022
Molecular structure recognition is the task of translating a molecular image into its graph structure. Significant variation in drawing styles and conventions exhibited in chemical literature poses a significant challenge for automating this task. In this paper, we propose MolScribe, a novel image-to-graph generation model that explicitly predicts ...
arxiv   +1 more source

Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes

open access: yesNature Communications, 2019
Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song   +3 more
doaj   +1 more source

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

open access: yes, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe   +100 more
core   +1 more source

Differential regulation of the Epr3 receptor coordinates membrane-restricted rhizobial colonization of root nodule primordia

open access: yesNature Communications, 2017
TheLotus japonicus LysM receptor kinase EPR3 perceives rhizobial exopolysaccharides to initiate infection of the root epidermis. Here the authors show that EPR3 also mediates infection thread progression in the root cortex and show that key transcription
Yasuyuki Kawaharada   +10 more
doaj   +1 more source

Bioinspired tetraamino-bisthiourea chiral macrocycles in catalyzing decarboxylative Mannich reactions

open access: yesBeilstein Journal of Organic Chemistry, 2022
A series of tetraamino-bisthiourea chiral macrocycles containing two diarylthiourea and two chiral diamine units were synthesized by a fragment-coupling approach in high yields.
Hao Guo   +3 more
doaj   +1 more source

Spiralling molecular structures and chiral selectivity in model membranes [PDF]

open access: yes, 2023
Since the lipid raft model was developed at the end of the last century, it became clear that the specific molecular arrangements of phospholipid assemblies within a membrane have profound implications in a vast range of physiological functions. Studies of such condensed lipid islands in model systems using fluorescence and Brewster angle microscopies ...
arxiv   +1 more source

Optimal Design of a Molecular Recognizer: Molecular Recognition as a Bayesian Signal Detection Problem [PDF]

open access: yesIEEE Journal of Selected Topics in Signal Processing, vol. 2, issue 3, pp. 390-399, 2008, 2010
Numerous biological functions-such as enzymatic catalysis, the immune response system, and the DNA-protein regulatory network-rely on the ability of molecules to specifically recognize target molecules within a large pool of similar competitors in a noisy biochemical environment.
arxiv   +1 more source

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