Results 141 to 150 of about 1,479 (165)

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C. [PDF]

Cell Rep
Miao J, Hara M, Su KC, Keys HR, Kong W, Takenoshita Y, Cheeseman IM, Fukagawa T.   +7 more
europepmc   +1 more source

Spastin regulates anaphase chromosome separation distance and microtubule-containing nuclear tunnels. [PDF]

Mol Biol Cell
Kelley ME, Carlini L, Kornakov N, Aher A, Khodjakov A, Kapoor TM.   +5 more
europepmc   +1 more source

Designing and the anticancer activity of chitosan and chitosan oligosaccharide lactate nanobeads loaded with Biginelli hybrid. [PDF]

RSC Adv
Janković N, Ristovski J, Žižak Ž, Radan M, Cvijić S, Nikolić K, Ignjatović NL.   +6 more
europepmc   +1 more source

Microtubule pivoting driven by spindle elongation rescues polar chromosomes to ensure faithful mitosis

Tolić I, Koprivec I, Stimac V, Mikec P.
europepmc   +1 more source

Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression

Vukušić K, Tolić IM.
europepmc   +1 more source

Enantioselective biocatalytic synthesis of (S)-monastrol

Bioorganic and Medicinal Chemistry Letters, 2010
Alfaro Blasco M, Thumann S, Wittmann J, Athanassios G, Gröger H. Enantioselective biocatalytic synthesis of (S)-monastrol. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.
Harald Groger
exaly   +2 more sources

Improved synthesis and preparative scale resolution of racemic monastrol

Tetrahedron Letters, 2002
The Yb(OTf)3 catalyzed Biginelli cyclocondensation reaction of 3-hydroxybenzaldehyde, ethyl acetoacetate and thiourea afforded the corresponding dihydropyrimidine-2-thione, called monastrol, in 95% isolated yield.
Alessandro Massi, Simona Sabbatini
exaly   +2 more sources

Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells

Naunyn-Schmiedeberg's Archives of Pharmacology, 2016
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundacao Araucaria, BrazilMonastrol is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an ...
Simone Cristine Semprebon, Andressa Megumi Niwa, Daniele Sartori   +2 more
exaly   +2 more sources

Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl-l-cysteine in tumor derived cell lines

Biochemical Pharmacology, 2010
The kinesin Eg5 plays an essential role in bipolar spindle formation. A variety of structurally diverse inhibitors of the human kinesin Eg5, including monastrol and STLC, share the same binding pocket on Eg5, composed by helix alpha 2/loop L5, and helix ...
Frank Kozielski, Dimitrios A Skoufias
exaly   +3 more sources