Results 11 to 20 of about 32,939 (178)

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

A first attempt into the production of acylglycerol mixtures from Echium oil

Frontiers in Bioengineering and Biotechnology, 2016
Enzymatic glycerolysis of Echium oil (Echium plantagineum) has been carried out in the presence of four commercial lipases. Different pretreatment of the reaction mixture, such as high pressure homogenization and addition of food grade monoolein as an ...
Luis eVázquez, Alejandro eJordán, Guillermo eReglero, Guillermo eReglero, Carlos F Torres   +4 more
doaj   +1 more source

Produção de monoacilgliceróis e diacilgliceróis via glicerólise enzimática e destilação molecular Production of monoglycerides and diglycerides through lipase-catalyzed glycerolysis and molecular distillation

Química Nova, 2009
Monoacilglycerides and diacilglycerides are produced through lipase-catalyzed glycerolysis of soybean oil using Candida antarctica B in a solvent-free system.
Patricia Bogalhos Lucente Fregolente, Gláucia Maria F. Pinto, Maria Regina Wolf-Maciel, Rubens Maciel Filho, César Benedito Batistella   +4 more
doaj   +1 more source

2-Arachidonoylglycerol Synthesis: Facile and Handy Enzymatic Method That Allows to Avoid Isomerization

Molecules, 2022
A simple and practical synthesis of 2-arachidonoyl glycerol (2-AG), an endogenous agonist for cannabinoid receptors, based on a two-step enzymatic process and a chemical coupling, was achieved with a good yield and negligible amount of the isomerization ...
Roberta Ottria, Silvana Casati, Paola Rota, Pierangela Ciuffreda   +3 more
doaj   +1 more source

Therapeutic potential of monoacylglycerol lipase inhibitors [PDF]

Life Sciences, 2013
Marijuana and aspirin have been used for millennia to treat a wide range of maladies including pain and inflammation. Both cannabinoids, like marijuana, that exert anti-inflammatory action through stimulating cannabinoid receptors, and cyclooxygenase (COX) inhibitors, like aspirin, that suppress pro-inflammatory eicosanoid production have shown ...
Melinda M, Mulvihill, Daniel K, Nomura
openaire   +2 more sources

Use of structured triacylglycerols containing predominantly stearic and oleic acids to probe early events in metabolic processing of dietary fat

Journal of Lipid Research, 1999
Early events in the metabolic processing of dietary triacylglycerol may have an important impact on subsequent development of risk factors for coronary heart disease.
Lucinda K.M. Summers, Barbara A. Fielding, Sara L. Herd, Vera Ilic, Mo L. Clark, Paul T. Quinlan, Keith N. Frayn   +6 more
doaj   +1 more source

Lipid oxidation in margarine emulsions

Czech Journal of Food Sciences, 2004
Influence of different storage atmosphere (argon and oxygen atmosphere) and influence of monoacylglycerol's emulsifier (with the carbon chain containing 10, 12, 14, 16, 18 carbon atoms and commercial emulsifier D and a model mixture of monoacylglycerols ...
I. Pokorná, V. Filip, J. Šmidrkal
doaj   +1 more source

Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus

Beilstein Journal of Organic Chemistry, 2023
A new antibacterial 3-monoacyl-sn-glycerol, nostochopcerol (1), was isolated from a cultured algal mass of the edible cyanobacterium Nostochopsis lobatus MAC0804NAN. The structure of compound 1 was established by the analysis of NMR and MS data while its
Naoya Oku, Saki Hayashi, Yuji Yamaguchi, Hiroyuki Takenaka, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Anti-Inflammatory Potential of Monogalactosyl Diacylglycerols and a Monoacylglycerol from the Edible Brown Seaweed Fucus spiralis Linnaeus

Marine Drugs, 2014
A monoacylglycerol (1) and a 1:1 mixture of two monogalactosyl diacylglycerols (MGDGs) (2 and 3) were isolated from the brown seaweed Fucus spiralis Linnaeus.
Graciliana Lopes, Georgios Daletos, Peter Proksch, Paula B. Andrade, Patrícia Valentão   +4 more
doaj   +1 more source