Results 21 to 30 of about 9,893 (179)

Therapeutic potential of monoacylglycerol lipase inhibitors [PDF]

Life Sciences, 2013
Marijuana and aspirin have been used for millennia to treat a wide range of maladies including pain and inflammation. Both cannabinoids, like marijuana, that exert anti-inflammatory action through stimulating cannabinoid receptors, and cyclooxygenase (COX) inhibitors, like aspirin, that suppress pro-inflammatory eicosanoid production have shown ...
Melinda M, Mulvihill, Daniel K, Nomura
openaire   +2 more sources

Properties of acyl-coenzyme A:1-acylglycerophosphate acyltransferase and lipases in porcine erythrocyte membranes.

Journal of Lipid Research, 1984
Acyl-CoA:1-acylglycerophosphate acyltransferase activity was found in porcine erythrocyte membranes. However, the membrane preparations did not catalyze the acylation of either 2-acylglycerophosphate or 2-acylglycerophosphocholine.
M Mizuno, Y Sugiura, H Okuyama
doaj   +1 more source

Preparation of thioester substrates and development of continuous spectrophotometric assays for phospholipase A1 and monoacylglycerol lipase

Journal of Lipid Research, 1981
Current assays of phospholipase A1 (EC 3.1.1.32) and monoacylglycerol lipase (EC 3.1.1.23) activities in tissues are discontinuous, laborious, and expensive. Some spectrophotometric substrates were synthesized to alleviate this problem. Thioester analogs
J W Cox, L A Horrocks
doaj   +1 more source

Glycerolysis of sardine oil catalyzed by a water dependent lipase in different tert-alcohols as reaction medium

Grasas y Aceites, 2015
The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols.
Á. G. Solaesa, M. T. Sanz, R. Melgosa, S. L. Bucio, S. Beltrán   +4 more
doaj   +1 more source

Strategies to inhibit the lipid oxidation in the enzymatic synthesis of monoglycerides by glycerolysis of Babassu oil - doi: 10.4025/actascitechnol.v35i3.14187

Acta Scientiarum: Technology, 2013
Different strategies to avoid the lipid feedstock oxidation in the enzymatic synthesis of monoglycerides (MAG) from glycerolysis of babassu oil were tested. The reactions were catalyzed by Burkholderia cepacia lipase immobilized on SiO2-PVA and the tests
Larissa Freitas, Gisanara Dors, Bruna Curry Carneiro, Pedro Carlos de Oliveira, Heizir Ferreira De Castro   +4 more
doaj   +1 more source

Monoacylmonoalkylglycerol as a substrate for diacylglycerol hydrolase activity in adipose tissue.

Journal of Lipid Research, 1978
The synthesis and use of 1(3)-[3H]oleoyl-2-0-oleylglycerol as a substrate for the assay of diacylglycerol hydrolase activity in adipose tissue is described.
H Tornqvist, P Björgell, L Krabisch, P Belfrage   +3 more
doaj   +1 more source

Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders

Acta Pharmaceutica Sinica B, 2020
Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays a crucial role catalysing the hydrolysis of monoglycerides into glycerol and fatty acids.
Hui Deng, Weimin Li
doaj   +1 more source

Bioorganic synthesis, characterization and evaluation of a natural phenolic lipid

Biotechnology Reports, 2019
The first synthesis of a phenolic natural monoacylglycerol (1- [11-(ferulyloxy) undecanoyl)] glycerol) was carried out by bioorganic synthesis starting from ferulic acid.
Juliya Johny, Venkateshwarlu Kontham, Dileep Veeragoni, Sunil Misra, Shiva Shanker Kaki   +4 more
doaj   +1 more source

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Journal of Lipid Research, 2015
Monoacylglycerol lipase (MGL) is a ubiquitously expressed enzyme that catalyzes the hydrolysis of monoacylglycerols (MGs) to yield FFAs and glycerol.
John D. Douglass, Yin Xiu Zhou, Amy Wu, John A. Zadrogra, Angela M. Gajda, Atreju I. Lackey, Wensheng Lang, Kristen M. Chevalier, Steven W. Sutton, Sui-Po Zhang, Christopher M. Flores, Margery A. Connelly, Judith Storch   +12 more
doaj   +1 more source

Biotechnological Valorization of Cupuaçu By-Products: Solid-State Fermentation for Lipase Production by Yarrowia lipolytica

Fermentation, 2023
Lipases are enzymes that catalyze the hydrolysis of ester bonds of triacylglycerols at the oil–water interface, generating free fatty acids, glycerol, diacylglycerol, and monoacylglycerol, which can be produced from the fermentation of agro-industrial by-
Aparecida Selsiane Sousa Carvalho, Raíssa de Carvalho Pinto e Rocha, Júlio Cesar Soares Sales, Carlos Eduardo Conceição de Souza, Ailton Cesar Lemes, Maria Alice Zarur Coelho   +5 more
doaj   +1 more source