Results 31 to 40 of about 68,881 (203)

Monoacylmonoalkylglycerol as a substrate for diacylglycerol hydrolase activity in adipose tissue.

Journal of Lipid Research, 1978
The synthesis and use of 1(3)-[3H]oleoyl-2-0-oleylglycerol as a substrate for the assay of diacylglycerol hydrolase activity in adipose tissue is described.
H Tornqvist, P Björgell, L Krabisch, P Belfrage   +3 more
doaj   +1 more source

Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders

Acta Pharmaceutica Sinica B, 2020
Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays a crucial role catalysing the hydrolysis of monoglycerides into glycerol and fatty acids.
Hui Deng, Weimin Li
doaj   +1 more source

ROG1 encodes a monoacylglycerol lipase in Saccharomyces cerevisiae [PDF]

, 2015
Lipid metabolism is extensively studied in Saccharomyces cerevisiae. Here, we report that revertant of glycogen synthase kinase mutation-1 (Rog1p) possesses monoacylglycerol (MAG) lipase activity in S. cerevisiae.
Vasanthi Nachiappan, Kandasamy Selvaraju, Vasanthi, Nachiappan, Vishnu Varthini, Lakshmanaperumal, Lakshmanaperumal Vishnu Varthini, Selvaraju, Kandasamy., Srinivasan, Malathi, Malathi Srinivasan, Nachiappan, Vasanthi, Varthini, Lakshmanaperumal Vishnu, Selvaraju, Kandasamy, Malathi, S.   +11 more
core   +1 more source

Structure-activity relationship studies of arylsulfoxides as reversible monoacylglycerol lipase inhibitors [PDF]

, 2023
Monoacylglyerol lipase (MAGL) is the key enzyme for the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG). The central role of MAGL in the metabolism of 2-AG makes it an attractive therapeutic target for a variety of disorders, including ...
Renze, Bakker, Avand, Amedi, Mirjam, Huizenga, Richard, van der Berg, Hui, Deng, Mario, van der Stelt, Ming, Jiang, Florian, Mohr, Constant, van Boeckel, Tom, van der Wel   +9 more
core   +2 more sources

Bioorganic synthesis, characterization and evaluation of a natural phenolic lipid

Biotechnology Reports, 2019
The first synthesis of a phenolic natural monoacylglycerol (1- [11-(ferulyloxy) undecanoyl)] glycerol) was carried out by bioorganic synthesis starting from ferulic acid.
Juliya Johny, Venkateshwarlu Kontham, Dileep Veeragoni, Sunil Misra, Shiva Shanker Kaki   +4 more
doaj   +1 more source

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Journal of Lipid Research, 2015
Monoacylglycerol lipase (MGL) is a ubiquitously expressed enzyme that catalyzes the hydrolysis of monoacylglycerols (MGs) to yield FFAs and glycerol.
John D. Douglass, Yin Xiu Zhou, Amy Wu, John A. Zadrogra, Angela M. Gajda, Atreju I. Lackey, Wensheng Lang, Kristen M. Chevalier, Steven W. Sutton, Sui-Po Zhang, Christopher M. Flores, Margery A. Connelly, Judith Storch   +12 more
doaj   +1 more source

Biotechnological Valorization of Cupuaçu By-Products: Solid-State Fermentation for Lipase Production by Yarrowia lipolytica

Fermentation, 2023
Lipases are enzymes that catalyze the hydrolysis of ester bonds of triacylglycerols at the oil–water interface, generating free fatty acids, glycerol, diacylglycerol, and monoacylglycerol, which can be produced from the fermentation of agro-industrial by-
Aparecida Selsiane Sousa Carvalho, Raíssa de Carvalho Pinto e Rocha, Júlio Cesar Soares Sales, Carlos Eduardo Conceição de Souza, Ailton Cesar Lemes, Maria Alice Zarur Coelho   +5 more
doaj   +1 more source

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

Journal of Lipid Research, 2012
In the central nervous system, three enzymes belonging to the serine hydrolase family are thought to regulate the life time of the endocannabinoid 2-arachidonoylglycerol (C20:4) (2-AG). From these, monoacylglycerol lipase (MAGL) is well characterized and,
Dina Navia-Paldanius, Juha R. Savinainen, Jarmo T. Laitinen   +2 more
doaj   +1 more source

Enzymatic and chemical synthesis of high mono- and diacylglycerol from palm stearin and olein blend at different type of reactor stirrers

Journal of the Saudi Society of Agricultural Sciences, 2020
The objective of this research was to synthesis structured lipid containing a high concentration of monoacylglycerol (MAG) and diacylglycerol (DAG) from palm stearin-olein blend.
Edy Subroto, Masrur Faida Wisamputri, Supriyanto, Tyas Utami, Chusnul Hidayat   +4 more
doaj   +1 more source

Inhibitors of monoacylglycerol lipase as novel analgesics [PDF]

British Journal of Pharmacology, 2007
2‐Arachidonoylglycerol (2‐AG) is an endogenous cannabinoid (endocannabinoid) lipid whose functions remain poorly understood. Guindon and colleagues report the novel finding that exogenous application of 2‐AG induces peripheral antinociceptive effects that are mediated, at least in part, by actions at peripheral cannabinoid CB2 receptors.
openaire   +2 more sources