Results 31 to 40 of about 11,083 (203)
Journal of Lipid Research, 1984 Acyl-CoA:1-acylglycerophosphate acyltransferase activity was found in porcine erythrocyte membranes. However, the membrane preparations did not catalyze the acylation of either 2-acylglycerophosphate or 2-acylglycerophosphocholine.
M Mizuno, Y Sugiura, H Okuyama
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Journal of Lipid Research, 1981 Current assays of phospholipase A1 (EC 3.1.1.32) and monoacylglycerol lipase (EC 3.1.1.23) activities in tissues are discontinuous, laborious, and expensive. Some spectrophotometric substrates were synthesized to alleviate this problem. Thioester analogs
J W Cox, L A Horrocks
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Grasas y Aceites, 2015 The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols.
Á. G. Solaesa +4 more
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Acta Scientiarum: Technology, 2013 Different strategies to avoid the lipid feedstock oxidation in the enzymatic synthesis of monoglycerides (MAG) from glycerolysis of babassu oil were tested. The reactions were catalyzed by Burkholderia cepacia lipase immobilized on SiO2-PVA and the tests
Larissa Freitas +4 more
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, 2023 Monoacylglyerol lipase (MAGL) is the key enzyme for the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG). The central role of MAGL in the metabolism of 2-AG makes it an attractive therapeutic target for a variety of disorders, including ...
Renze, Bakker +9 more
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Inhibitors of monoacylglycerol lipase as novel analgesics [PDF]
British Journal of Pharmacology, 2007 2‐Arachidonoylglycerol (2‐AG) is an endogenous cannabinoid (endocannabinoid) lipid whose functions remain poorly understood. Guindon and colleagues report the novel finding that exogenous application of 2‐AG induces peripheral antinociceptive effects that are mediated, at least in part, by actions at peripheral cannabinoid CB2 receptors.
openaire +2 more sources
Monoacylglycerol lipase: stopping surplus at the synapse
The Journal of Physiology, 2011 Endocannabinoids (eCBs) are a family of molecules derived from membrane phospholipids which exert biological effects through specific receptors. In the brain, eCBs are perhaps the most ubiquitous and potent neurotransmitters known to act in a retrograde manner.
Jaclyn I, Wamsteeker, Jaideep S, Bains
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Distribution and function of monoacylglycerol lipase in the gastrointestinal tract [PDF]
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2008 The endogenous cannabinoid system plays an important role in the regulation of gastrointestinal function in health and disease. Endocannabinoid levels are regulated by catabolic enzymes. Here, we describe the presence and localization of monoacylglycerol lipase (MGL), the major enzyme responsible for the degradation of 2-arachidonoylglycerol.
Duncan, Marnie +8 more
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Monoacylmonoalkylglycerol as a substrate for diacylglycerol hydrolase activity in adipose tissue.
Journal of Lipid Research, 1978 The synthesis and use of 1(3)-[3H]oleoyl-2-0-oleylglycerol as a substrate for the assay of diacylglycerol hydrolase activity in adipose tissue is described.
H Tornqvist +3 more
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Acta Pharmaceutica Sinica B, 2020 Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays a crucial role catalysing the hydrolysis of monoglycerides into glycerol and fatty acids.
Hui Deng, Weimin Li
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