Results 41 to 50 of about 125,969 (167)

Seed storage oil mobilization is important but not essential for germination or seedling establishment in Arabidopsis [PDF]

, 1992
Triacylglycerol (TAG) is a major storage reserve in many plant seeds. We previously identified a TAG lipase mutant called sugar-dependent1 (sdp1) that is impaired in TAG hydrolysis following Arabidopsis (Arabidopsis thaliana) seed germination (Eastmond,
Kelly, Amélie A., Quettier, Anne-Laure, Shaw, Eve, Eastmond, Peter J.   +3 more
core   +2 more sources

Glicerolisis de aceite de sardina catalizada por una lipasa dependiente de agua en diferentes tert-alcoholes como medio de reacción [PDF]

, 2015
The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols. Based on the phase equilibrium data,
Beltrán Calvo, Sagrario, Bucio López, Silvia Liliana, García Solaesa, Ángela, Melgosa Gómez, Rodrigo, Sanz Díez, Mª Teresa   +4 more
core   +3 more sources

Robust anti-nociceptive effects of MAG lipase inhibition in a model of osteoarthritis pain [PDF]

, 2016
BACKGROUND AND PURPOSE: Chronic pain is often a symptom of knee osteoarthritis (OA) for which current analgesics are either inadequate, or are associated with serious side effects. The endocannabinoid system may offer alternative targets for pain-relief.
Alexander, Alexander, Burston, Chan, Chen, Christiansen, Curtis, Elikkottil, Glyn-Jones, Goldring, Gonsiorek, Huffman, Huggins, Ignatowska-Jankowska, Janusz, Juni, Kelly, Kilkenny, Kinsey, Lee, Long, Lysenko, Mapp, McGrath, Niphakis, Nomura, Ogbonna, Okine, Parker, Rani Sagar, Sagar, Sagar, Sagar, Sagar, Sasso, Savinainen, Schlosburg, Sinikallio, Smith, Southan, Woodhams, Yu, Zhang, Zhang   +43 more
core   +5 more sources

Prebiotic effects of wheat Arabinoxylan related to the increase in Bifidobacteria, Roseburia and bacteroides/Prevotella in diet-induced obese mice [PDF]

, 2011
Background: Alterations in the composition of gut microbiota - known as dysbiosis - has been proposed to contribute to the development of obesity, thereby supporting the potential interest of nutrients targeting the gut with beneficial effect for host ...
Neyrinck, Audrey M, Possemiers, Sam, Druart, Celine, Van de Wiele, Tom, De Backer, Fabienne, Cani, Patrice D, Larondelle, Yvan, Delzenne, Nathalie M   +7 more
core   +2 more sources

Diacylglycerol oil for the metabolic syndrome [PDF]

, 2007
Excess adiposity has been shown to play a crucial role in the development of the metabolic syndrome. The elevated fasting and postprandial triglyceride-rich lipoprotein levels is the central lipid abnormality observed in the metabolic syndrome.
Hidekatsu Yanai, Yoshiharu Tomono, Kumie Ito, Nobuyuki Furutani, Hiroshi Yoshida, Norio Tada, G Ruotolo, N Tada, AA Abdel-Nabey, RP D'alonzo, LY Yang, J Cao, D Cheng, DA White, H Watanabe, HI Friedman, K Yasunaga, HJ Kim, A Fujii, S Meguro, N Tada, K Tomonobu, N Tada, H Takase, K Yamamoto, T Yasukawa, Y Katsuragi, K Otsuki, WC Breckenridge, H Yanai, S Kimura, S Saito, T Murase, T Murase, HJ Kim, S Saito, KC Maki, T Nagao, W Koyama, T Matsuyama, I Rudkowska, H Tsuda, CP Chengelis, CP Chengelis, CP Chengelis   +44 more
core   +2 more sources

Conformational gating, dynamics and allostery in human monoacylglycerol lipase. [PDF]

Sci Rep, 2020
Inhibition of human Monoacylglycerol Lipase (hMGL) offers a novel approach for treating neurological diseases. The design of inhibitors, targeting active-inactive conformational transitions of the enzyme, can be aided by understanding the interplay ...
Tyukhtenko S, Ma X, Rajarshi G, Karageorgos I, Anderson KW, Hudgens JW, Guo JJ, Nasr ML, Zvonok N, Vemuri K, Wagner G, Makriyannis A.   +11 more
europepmc   +2 more sources

Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease. [PDF]

World J Gastroenterol, 2020
Dietary oversupply of triglycerides represent the hallmark of obesity and connected complications in the liver such as non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, which eventually progress to cirrhosis and hepatocellular ...
Tardelli M.
europepmc   +2 more sources

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease

Theranostics, 2020
Rationale: Monoacylglycerol lipase (Mgll), a hydrolase that breaks down the endocannabinoid 2-arachidonoyl glycerol (2-AG) to produce arachidonic acid (ARA), is a potential target for neurodegenerative diseases, such as Alzheimer's disease (AD ...
Charvi Syal, Jayasankar Kosaraju, Laura K. Hamilton, A. Aumont, Alphonse Chu, Sailendra Nath, Sarma, Jacob Thomas, Matthew Seegobin, F. J. Dilworth, Ling He, F. Wondisford, Robert, Zimmermann, M. Parent, K. Fernandes, Jing Wang   +16 more
semanticscholar   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source