Results 41 to 50 of about 11,083 (203)

Bioorganic synthesis, characterization and evaluation of a natural phenolic lipid

Biotechnology Reports, 2019
The first synthesis of a phenolic natural monoacylglycerol (1- [11-(ferulyloxy) undecanoyl)] glycerol) was carried out by bioorganic synthesis starting from ferulic acid.
Juliya Johny, Venkateshwarlu Kontham, Dileep Veeragoni, Sunil Misra, Shiva Shanker Kaki   +4 more
doaj   +1 more source

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Journal of Lipid Research, 2015
Monoacylglycerol lipase (MGL) is a ubiquitously expressed enzyme that catalyzes the hydrolysis of monoacylglycerols (MGs) to yield FFAs and glycerol.
John D. Douglass, Yin Xiu Zhou, Amy Wu, John A. Zadrogra, Angela M. Gajda, Atreju I. Lackey, Wensheng Lang, Kristen M. Chevalier, Steven W. Sutton, Sui-Po Zhang, Christopher M. Flores, Margery A. Connelly, Judith Storch   +12 more
doaj   +1 more source

Biotechnological Valorization of Cupuaçu By-Products: Solid-State Fermentation for Lipase Production by Yarrowia lipolytica

Fermentation, 2023
Lipases are enzymes that catalyze the hydrolysis of ester bonds of triacylglycerols at the oil–water interface, generating free fatty acids, glycerol, diacylglycerol, and monoacylglycerol, which can be produced from the fermentation of agro-industrial by-
Aparecida Selsiane Sousa Carvalho, Raíssa de Carvalho Pinto e Rocha, Júlio Cesar Soares Sales, Carlos Eduardo Conceição de Souza, Ailton Cesar Lemes, Maria Alice Zarur Coelho   +5 more
doaj   +1 more source

Inhibition of monoacylglycerol lipase reduces nicotine withdrawal [PDF]

British Journal of Pharmacology, 2015
Background and PurposeAbrupt discontinuation of nicotine, the main psychoactive component in tobacco, induces a withdrawal syndrome in nicotine‐dependent animals, consisting of somatic and affective signs, avoidance of which contributes to drug maintenance.
P P, Muldoon, J, Chen, J L, Harenza, R A, Abdullah, L J, Sim-Selley, B F, Cravatt, M F, Miles, X, Chen, A H, Lichtman, M I, Damaj   +9 more
openaire   +2 more sources

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

Journal of Lipid Research, 2012
In the central nervous system, three enzymes belonging to the serine hydrolase family are thought to regulate the life time of the endocannabinoid 2-arachidonoylglycerol (C20:4) (2-AG). From these, monoacylglycerol lipase (MAGL) is well characterized and,
Dina Navia-Paldanius, Juha R. Savinainen, Jarmo T. Laitinen   +2 more
doaj   +1 more source

Stimulatory and Inhibitory Roles of Brain 2-Arachidonoylglycerol in Bombesin-Induced Central Activation of Adrenomedullary Outflow in Rats

Journal of Pharmacological Sciences, 2013
2-Arachidonoylglycerol (2-AG) is recognized as a potent endocannabinoid, which reduces synaptic transmission through cannabinoid CB1 receptors, and is hydrolyzed by monoacylglycerol lipase (MGL) to arachidonic acid (AA), a cyclooxygenase substrate.
Takahiro Shimizu, Kenjiro Tanaka, Kunihiko Yokotani   +2 more
doaj   +1 more source

Enzymatic and chemical synthesis of high mono- and diacylglycerol from palm stearin and olein blend at different type of reactor stirrers

Journal of the Saudi Society of Agricultural Sciences, 2020
The objective of this research was to synthesis structured lipid containing a high concentration of monoacylglycerol (MAG) and diacylglycerol (DAG) from palm stearin-olein blend.
Edy Subroto, Masrur Faida Wisamputri, Supriyanto, Tyas Utami, Chusnul Hidayat   +4 more
doaj   +1 more source

Purification and properties of a monoacylglycerol lipase in human erythrocytes [PDF]

Biochemical Journal, 1995
A membrane-bound monoacylglycerol lipase (MAGL) activity, previously demonstrated in intact human erythrocytes [Boyer, Somma, Vérine, L'Hôte, Finidori, Merger and Arnaud (1981) J. Clin. Endocrinol. Metab. 53, 143-148], has now been purified to apparent homogeneity by a five-step procedure involving solubilization in CHAPS and sequential ...
C, Somma-Delpéro, A, Valette, J, Lepetit-Thévenin, O, Nobili, J, Boyer, A, Vérine   +5 more
openaire   +2 more sources

N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase

Biotechnology for Biofuels, 2019
Background Lipolytic enzymes of hyperthermophilic archaea generally prefer small carbon chain fatty acid esters (C2–C12) and are categorized as esterases.
Surabhi Soni, Sneha S. Sathe, Rutuja R. Sheth, Prince Tiwari, Rajesh-Kumar N. Vadgama, Annamma Anil Odaneth, Arvind M. Lali, Sanjeev K. Chandrayan   +7 more
doaj   +1 more source

Characterization of a monoacylglycerol lipase in the medicinal leech, Hirudo verbana. [PDF]

Comp Biochem Physiol B Biochem Mol Biol, 2020
Endocannabinoids are a class of lipid neuromodulators found throughout the animal kingdom. Among the endocannabinoids, 2-arachydonoyl glycerol (2-AG) is the most prevalent endocannabinoid and monoacylglycerol lipase (MAGL) is a serine hydrolase primarily responsible for metabolizing 2-AG in mammals. In the medicinal leech, Hirudo verbana, 2-AG has been
Kabeiseman E, Paulsen R, Burrell BD.
europepmc   +4 more sources