Results 91 to 100 of about 737,831 (351)

Multiparameter Flow Cytometric Analysis of the Conventional and Monocyte-Derived DC Compartment in the Murine Spleen

Vaccines
Dendritic cells (DCs) are present in almost all tissues, where they act as sentinels involved in innate recognition and the initiation of adaptive immune responses.
Ronald A. Backer, Hans Christian Probst, Björn E. Clausen   +2 more
doaj   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT, Bednar MM, Bellosta S, Buttrum SM, Buyon JP, Calara F, Calderon TM, Diacovo TG, Giroux LM, Jukema JW, Kim JA, Kimura M, Laufs U, Laws KH, Lehr H-A, Marcus AJ, Notabartolo A, Olstrowsky L, Pons F, Ruf A, Smalley DM, Stragliotto E, Sugiyama S, Weber C, Weber C, Weber C, Yeagle PL, Yeo EL, Yue TL   +28 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Immunotoxicity Study of Cucurbit[n]urils (n = 6, 7, 8) and Modeling of Interaction with Some Monocyte Receptors by a Molecular Docking Method

Molecules
In this study, cucurbit[n]urils (n = 6, 7, 8) were carefully evaluated for their cytotoxicity and immunotoxicity to human peripheral blood monocytes. The cytotoxicity was studied by evaluating the survival of monocytes, while the immunotoxicity level was
Saule B. Zhautikova, Nursipat N. Abdykhanova, Dmitry A. Fedorishin, Yelena G. Shapovalova, Andrei I. Khlebnikov, Abdigali A. Bakibaev, Irina A. Kurzina, Saule K. Kabieva, Nazerke Boranbay, Gaziza M. Zhumanazarova   +9 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Phenotype and function of human monocytes remain mainly unaffected by very small superparamagnetic iron oxide particles

Frontiers in Nanotechnology
The field of medical application of organic or inorganic nanoparticles is extensive. Medical nanoparticles offer benefits but pose risks. For safe use in diagnostics and therapy, they should be inert, non-immunogenic, non-aggregating, and avoid long-term
Sari Hussein, Sari Hussein, Anja Andrea Kühl, Laura Golusda, Laura Golusda, Christina Plattner, Nadine Heinze, Nadine Heinze, Gregor Sturm, Christian Freise, Heike Traub, Mathias Schannor, Zlatko Trajanoski, Matthias Taupitz, Britta Siegmund, Daniela Paclik, Daniela Paclik   +16 more
doaj   +1 more source

Synovial tissue macrophages: friend or foe? [PDF]

, 2017
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Alivernini, Stefano, Kurowska-Stolarska, Mariola   +1 more
core   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Cell population data analysis for early diagnosis and prognosis of COVID-19: A Case-Control Study [PDF]

Medical Laboratory Journal
Background: Several hematological indicators have been linked to the intensity and course of Coronavirus Disease of 2019 (COVID-19), including platelets, total white blood cell (WBC) count, lymphocytes, neutrophils (as well as the neutrophil-lymphocyte ...
Priyadarshini Kumaraswamy Rajeswaran, Preethi Muthusamy Sundar, Prasanna Nedungadi Kumar, Karthikeyan Shanmugam   +3 more
doaj  

Evaluation of Lipid-Based Transfection in Primary Monocytes Within an Ex Vivo Whole-Blood Model

Biomolecules
Transfection is a fundamental method in biomedical research to study intracellular molecular mechanisms by manipulating target protein expression. Various methods have been developed to deliver nucleic acids into the cells of interest in vitro, with ...
Robin Moolan-Vadackumchery, Lan Zhang, Frank Stüber   +2 more
doaj   +1 more source