Results 51 to 60 of about 7,647 (170)

The Cholesterol-Binding Sequence in Monomeric C-Reactive Protein Binds to the SARS-CoV-2 Spike Receptor-Binding Domain and Blocks Interaction With Angiotensin-Converting Enzyme 2

Frontiers in Immunology, 2022
The receptor-binding domain (RBD) of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the human angiotensin-converting enzyme 2 (ACE2) receptor, which is a prerequisite for the virus to enter the cell. C-reactive
Hai-yun Li, Hai-yun Li, Ning Gao, Cheng-yang Liu, Xiao-ling Liu, Feng Wu, Nini Dai, Jing Han, Jing Han, Qiu-yu Li   +9 more
doaj   +1 more source

Neuroinflammation in Preclinical Alzheimer's Disease: A Review of Current Evidence [PDF]

, 2018
The pathology of sporadic Alzheimer’s disease (AD) may be present at mid-life and precede the prodromal and clinical dementia syndromes associated with the disorder by decades.
Raymont, Vanessa, Ritchie, Karen, Watermeyer, Tamlyn   +2 more
core   +2 more sources

Relevance of lipoproteins, membranes, and extracellular vesicles in understanding C-reactive protein biochemical structure and biological activities

Frontiers in Cardiovascular Medicine, 2022
Early purification protocols for C-reactive protein (CRP) often involved co-isolation of lipoproteins, primarily very low-density lipoproteins (VLDLs).
Lawrence A. Potempa, Wei Qiao Qiu, Wei Qiao Qiu, Wei Qiao Qiu, Ashley Stefanski, Ibraheem M. Rajab   +5 more
doaj   +1 more source

Serratamolide is a hemolytic factor produced by Serratia marcescens [PDF]

, 2012
Serratia marcescens is a common contaminant of contact lens cases and lenses. Hemolytic factors of S. marcescens contribute to the virulence of this opportunistic bacterial pathogen.
BA Holden, CS Lin, D Dwivedi, DDawsonDS Burke, E Escobar-Diaz, E Hume, E Kessler, E Pradel, EJ Kalivoda, EJ Kalivoda, G Menestrina, H Li, HD Kulasekara, HH Wasserman, HH Wasserman, IK Gipson, K Shimuta, K Steppberger, KB Marty, LD Hazlett, M Dalla Serra, M Givskov, M Givskov, Mark Alexander Webber, ME Marquart, MJ Wargo, ML Hutchison, MM Nakano, MT Butler, NA Stella, NC Shaner, Nicholas A. Stella, NR Williamson, PA Grimont, PW Lindum, PZ Wu, R Bar-Ness, R Gaynes, R Hertle, Regis P. Kowalski, RM Shanks, RM Shanks, RM Shanks, Robert M. Q. Shanks, Roni M. Lahr, RP Vonberg, RP Williams, S Bhakdi, S Letoffe, Shaoru Wang, SL Chiang, T Matsuyama, T Matsuyama, T Tanikawa, Tara I. Veverka, V Soto-Cerrato, W Haas, Xinyu Liu, Y Li, Y Miyazaki, Y Miyazaki, YH Hsueh   +61 more
core   +5 more sources

C-Reactive Protein and Cancer: Interpreting the Differential Bioactivities of Its Pentameric and Monomeric, Modified Isoforms

Frontiers in Immunology, 2021
C-reactive protein (CRP) was first recognized in the 1940s as a protein that appeared in blood during acute episodes of infectious disease. Its presence and pharmacodynamics were found in essentially all diseases that involved tissue damage and ...
Lawrence A. Potempa, Ibraheem M. Rajab, Margaret E. Olson, Peter C. Hart   +3 more
doaj   +1 more source

Cocoa polyphenols and inflammatory markers of cardiovascular disease [PDF]

, 2015
Epidemiological studies have demonstrated the beneficial effect of plant-derived food intake in reducing the risk of cardiovascular disease (CVD). The potential bioactivity of cocoa and its polyphenolic components in modulating cardiovascular health is ...
Andrés Lacueva, Ma. Cristina, Garcia Aloy, Mar, Khan, Nasiruddin, Khymenets, Olha, Llorach, Rafael, Monagas, Maria, Mora Cubillos, Lyda Ximena, Tulipani, Sara, Urpí Sardà, Mireia   +8 more
core   +1 more source

FÖRSTER TRANSFER CALCULATIONS BASED ON CRYSTAL STRUCTURE DATA FROM Agmenellum quadruplicatum C-PHYCOCYANIN [PDF]

, 1987
Excitation energy transfer in C-phycocyanin is modeled using the Forster inductive resonance mechanism. Detailed calculations are carried out using coordinates and orientations of the chromophores derived from X-ray crystallographic studies of C ...
Cogdell R. J., Dale R. E., Forster T., Glazer A. N., Grabowski J., Grabowski J., Hefferle P., Hefferle P., Holzwarth A. R., Holzwarth A. R., John W., Lehner H., Lundell D. J., MacColl R., Sauer K., Sauer K., Scheer H., Schneider, Schneider S., Shampine L. F., Siebzehnriibl S., Switalski S. C., Teale F. W. J., Wendler J.   +23 more
core   +1 more source

The Role of Anti-mCRP Autoantibodies in Lupus Nephritis

Kidney Diseases, 2023
Background: Lupus nephritis is characterized by multiple autoantibodies production. However, there are few autoantibodies associated with disease activity and prognosis.
Mo Yuan, Ying Tan, Ming-hui Zhao
doaj   +1 more source

Biomarkers of acute kidney injury [PDF]

, 2011
Acute kidney injury (AKI) is a common and potentially fatal complication in critically ill patients. The diagnosis relies on functional markers of decreased glomerular filtration rate (GFR) such as creatinine. Unfortunately, a rise in plasma creatinine
Mårtensson, Johan
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source