Results 31 to 40 of about 54,444 (297)

Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma. [PDF]

open access: yes, 2020
Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to subsequently modify PTSD-related behavior has not been well ...
Evans, Christopher J   +6 more
core   +1 more source

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

open access: yes, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh   +6 more
core   +1 more source

Tourniquetless Total Knee Arthroplasty With Modern Perioperative Protocols Decreases Pain and Opioid Consumption in Women [PDF]

open access: yes, 2018
Background This study examined whether a modern total knee arthroplasty (TKA) protocol without a tourniquet results in less patient-reported pain and in-hospital opioid consumption compared to TKA with a tourniquet.
Dilley, Julian E.   +4 more
core   +1 more source

PolyMorphine provides extended analgesic-like effects in mice with spared nerve injury. [PDF]

open access: yes, 2017
Morphine is a well-characterized and effective analgesic commonly used to provide pain relief to patients suffering from both acute and chronic pain conditions.
Chen, Renxun   +5 more
core   +1 more source

Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring

open access: yesJournal of Biomedical Science, 2009
Co-administration of dextromethorphan (DM) with morphine during pregnancy and throughout lactation has been found to reduce morphine physical dependence and tolerance in rat offspring.
Tao Pao-Luh   +3 more
doaj   +1 more source

Influence of Selective Dopamine Agonist Ropinirole on Conditioned Place Preference and Somatic Signs of Morphine Withdrawal in Rats

open access: yesFrontiers in Behavioral Neuroscience, 2022
The underlying mechanism of dependence and rewarding effects of morphine is imperative to understand. The primary aim of this study was to investigate whether ropinirole D2/3 agonist affects the rewarding and reinforcing properties of morphine-induced ...
Andleeb Shahzadi   +7 more
doaj   +1 more source

Current evidence for a modulation of low back pain by human genetic variants [PDF]

open access: yes, 2009
The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration
Aberle   +200 more
core   +1 more source

Neuropsychological correlates of opioid dependence and withdrawal [PDF]

open access: yes, 2003
Severity of opioid dependence, and performance on two successive runs of the Wisconsin Card Sorting Test (WCST), were assessed in 39 right-handed male and female methadone patients who had been randomly assigned to either a recently dosed (n=21) or 24 hr
Lyvers, Michael, Yakimoff, Michael
core   +1 more source

Fatal dependence on kaolin and morphine mixture [PDF]

open access: yesPostgraduate Medical Journal, 1980
Summary A patient is described who had a long history of abuse of kaolin and morphine mixture which ultimately proved fatal.
J M, Barragry, D V, Morris
openaire   +2 more sources

Female rat hippocampal cell density after conditioned place preference [PDF]

open access: yes, 2014
The hippocampus is important for learning tasks, such as conditioned place preference (CPP), which is widely used as a model for studying the reinforcing effects of drugs with dependence liability.
Babakordi, F.   +3 more
core  

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