Results 71 to 80 of about 25,416 (201)

Olanzapine Attenuates the Morphine‐Induced Conditioned Place Preference: The Involvement of the D2‐Like Dopamine Receptors

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
The results of this study demonstrated that olanzapine can inhibit morphine‐induced CPP behavior during the acquisition, expression, and extinction phases. These effects are likely mediated by the inhibition of dopamine receptors and a reduction in D2R protein expression in the HIP.
Farkhondeh Rzazzaghi‐ Firozjaei   +6 more
wiley   +1 more source

The Effect of Nitric Oxide Microinjection in Nucleus Accumbens Shell on Morphine Withdrawal Signs in Male Rats [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2005
Introduction: This study was performed to evaluate the effects of intra-nucleus accumbens shell microinjection of Larginine (NO precursor) and L-NAME (nitric oxide synthase (NOS) inhibitor) on morphine withdrawal signs in male rats.
V Sheibani   +3 more
doaj  

Crosstalk between G protein-coupled receptors (GPCRs) and tyrosine kinase receptor (TXR) in the heart after morphine withdrawal

open access: yesFrontiers in Pharmacology, 2013
G protein-coupled receptors (GPCRs) comprise a large family of membrane receptors involved in signal transduction. These receptors are linked to a variety of physiological and biological processes such as regulation of neurotransmission, growth and cell ...
Pilar eAlmela   +4 more
doaj   +1 more source

The Association Between Partner Reactions to Chronic Pain and Pain‐Related Outcomes: A Systematic Review

open access: yesEuropean Journal of Pain, Volume 30, Issue 3, March 2026.
ABSTRACT Background and Objective It has long been recognised that the social context, including partner relationships, can impact the chronic pain experience and pain outcomes. The goal of this systematic review is to analyse, appraise and integrate the current evidence regarding the relationships between partner reactions to chronic pain behaviours ...
G. F. Donohue   +4 more
wiley   +1 more source

Pain Experience and Patient‐Reported Barriers to Analgesic Use in Emergency Care in Ghana: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Effective pain management remains a critical component of emergency care. However, patient‐related beliefs and misconceptions about pain medication can pose significant barriers to adequate analgesia. The aim of the study was to assess patient‐reported barriers to pain medication use and outcome in an emergency setting in ...
Stephen Mensah Arhin   +7 more
wiley   +1 more source

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

open access: yesMedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman   +7 more
wiley   +1 more source

Effect of Rosmarinus officinalis L. Aerial Parts Extract and Fractions on Morphine Withdrawal Syndrome in Mice

open access: yesJournal of Medicinal Plants, 2006
Background: Our previous studies have shown that the aqueous and ethanolic extracts of Rosmarinus officinalis L. aerial parts reduce morphine withdrawal syndrome in mice. Objective: As R. officinalis L.
H Hosseinzadeh   +2 more
doaj  

Implementation and Evaluation of a Pediatric Pain Education Program for Healthcare Providers in Ghana: A Multidisciplinary Approach

open access: yesPaediatric and Neonatal Pain, Volume 8, Issue 1, March 2026.
ABSTRACT Pediatric pain remains one of the inadequately managed conditions in clinical practice, especially in low‐resource settings, due in part to limited training across health professions. Addressing this gap requires a coordinated, multidisciplinary approach to improve pain assessment and management in children.
Abigail Kusi Amponsah   +11 more
wiley   +1 more source

Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024

open access: yesJournal of Forensic Sciences, Volume 71, Issue 2, Page 821-836, March 2026.
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr   +4 more
wiley   +1 more source

Psilocybin and Ibogaine in Cocaine‐Seeking: Extinction Enhancement Without Relapse Prevention

open access: yesAddiction Biology, Volume 31, Issue 3, March 2026.
Using a preclinical model of cocaine self‐administration, we examined the effects of psilocybin and ibogaine on extinction learning and relapse‐like behaviour. Both compounds, administered during the extinction phase, reduced cocaine seeking, indicating facilitation of extinction learning. However, neither treatment prevented cue‐induced reinstatement.
Isis Rita Anzel Koutrouli   +16 more
wiley   +1 more source

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