Results 71 to 80 of about 25,416 (201)
The results of this study demonstrated that olanzapine can inhibit morphine‐induced CPP behavior during the acquisition, expression, and extinction phases. These effects are likely mediated by the inhibition of dopamine receptors and a reduction in D2R protein expression in the HIP.
Farkhondeh Rzazzaghi‐ Firozjaei +6 more
wiley +1 more source
The Effect of Nitric Oxide Microinjection in Nucleus Accumbens Shell on Morphine Withdrawal Signs in Male Rats [PDF]
Introduction: This study was performed to evaluate the effects of intra-nucleus accumbens shell microinjection of Larginine (NO precursor) and L-NAME (nitric oxide synthase (NOS) inhibitor) on morphine withdrawal signs in male rats.
V Sheibani +3 more
doaj
G protein-coupled receptors (GPCRs) comprise a large family of membrane receptors involved in signal transduction. These receptors are linked to a variety of physiological and biological processes such as regulation of neurotransmission, growth and cell ...
Pilar eAlmela +4 more
doaj +1 more source
ABSTRACT Background and Objective It has long been recognised that the social context, including partner relationships, can impact the chronic pain experience and pain outcomes. The goal of this systematic review is to analyse, appraise and integrate the current evidence regarding the relationships between partner reactions to chronic pain behaviours ...
G. F. Donohue +4 more
wiley +1 more source
ABSTRACT Background and Aims Effective pain management remains a critical component of emergency care. However, patient‐related beliefs and misconceptions about pain medication can pose significant barriers to adequate analgesia. The aim of the study was to assess patient‐reported barriers to pain medication use and outcome in an emergency setting in ...
Stephen Mensah Arhin +7 more
wiley +1 more source
MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman +7 more
wiley +1 more source
Background: Our previous studies have shown that the aqueous and ethanolic extracts of Rosmarinus officinalis L. aerial parts reduce morphine withdrawal syndrome in mice. Objective: As R. officinalis L.
H Hosseinzadeh +2 more
doaj
ABSTRACT Pediatric pain remains one of the inadequately managed conditions in clinical practice, especially in low‐resource settings, due in part to limited training across health professions. Addressing this gap requires a coordinated, multidisciplinary approach to improve pain assessment and management in children.
Abigail Kusi Amponsah +11 more
wiley +1 more source
Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr +4 more
wiley +1 more source
Psilocybin and Ibogaine in Cocaine‐Seeking: Extinction Enhancement Without Relapse Prevention
Using a preclinical model of cocaine self‐administration, we examined the effects of psilocybin and ibogaine on extinction learning and relapse‐like behaviour. Both compounds, administered during the extinction phase, reduced cocaine seeking, indicating facilitation of extinction learning. However, neither treatment prevented cue‐induced reinstatement.
Isis Rita Anzel Koutrouli +16 more
wiley +1 more source

