Results 61 to 70 of about 226,399 (222)
, 2011 Previous studies have implicated the bed nucleus of the stria terminalis, central nucleus of the amygdala and the shell of the nucleus accumbens (collectively called the extended amygdala) as playing an important role in mediating the aversive emotion ...
Li, Sa +7 more
core +1 more source
The Contributions of the Gut Microbiome in Somatic Morphine Withdrawal [PDF]
Millions of people suffer from opioid use disorder (OUD) as a result of the ongoing opioid epidemic that has led to over 120,000 overdose related deaths worldwide.
Truitt, Bridget
core +4 more sources
Scientific ReportsMorphine, a potent opioid analgesic, is limited in clinical use due to tolerance, dependence, and withdrawal. Recent research highlights the gut microbiota as a crucial regulator of opioid effects through the microbiota-gut-brain axis.
Zahra Jokar +5 more
doaj +1 more source
Journal of Evidence-Based Medicine, EarlyView.ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li +7 more
wiley +1 more source
Basic and Clinical Neuroscience, 2013 Introduction: Calcium/calmodulin-dependent protein kinase II (CaMKII) is highly expressed in the hippocampus, which has a pivotal role in reward-related memories and morphine dependence.
Shamseddin Ahmadi +3 more
doaj
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim Infants exposed to alcohol and/or drugs (AoD) in utero are at considerable risk for developmental complications which are amenable to early intervention. There are no published guidelines in Australia for the allied health care of infants and toddlers (0–2 years) who have been exposed to AoD in utero.
Marla Laverie +9 more
wiley +1 more source
CONDITIONED MORPHINE WITHDRAWAL
, 2001 Many studies have demonstrated the important contribution of Pavlovian conditioning to the phenomena of drug tolerance and withdrawal. In the Pavlovian analysis, cues that are paired with drug administration come to elicit compensatory responses in ...
McDonald, Robert V.
core +1 more source
Enkephalinergic Neurons in the Periaqueductal Gray and Morphine Withdrawal
Japanese Journal of Pharmacology, 2000 The effects of opioid (e.g., morphine) withdrawal on levels of endogenous opioid peptides and their mRNA in the various brain regions have been studied. However, the role of this opioidergic mechanism in the mediation of opioid withdrawal is not fully understood.
Fukunaga, Yuko, Kishioka, Shiroh
openaire +3 more sources
Psychiatry and Clinical Neurosciences, EarlyView.Substance‐use disorders are increasingly linked to structural and functional brain alterations consistent with neuroaxonal injury. Neurofilament light chain (NfL) is a sensitive blood‐based marker of axonal damage, but evidence in substance‐using populations remains fragmented.
João Antônio Valadão Leal +2 more
wiley +1 more source
Ascorbic acid effect on morphine withdrawal symptoms in rats
Journal of Craniomaxillofacial Research, 2021 Introduction: Today, drug addiction is an important healthcare issue. Any helps to drug withdrawal may decrease its prevalence in the society. Ascorbic acid is a component, which can affect neurotransmitter systems as a regulator along with its ...
Abdollah Farhadi Nasab +2 more
doaj