Results 61 to 70 of about 55,011 (233)

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, EarlyView.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Evaluation of the Effects of Chronic Administration of Citrus aurantium Essential Oil on the Development of Tolerance and Dependence to Morphine [PDF]

Pharmaceutical Sciences, 2019
Background: Long-term exposure to opioids may lead to physical dependence and tolerance. The purpose of this study was to investigate the effects of Citrus aurantium essential oil (CEO) on the morphine-induced tolerance and dependence.
Alireza Parvizpur, Kosar Parnian, Sama Samankan, Fatemeh Fathiazad, Mohammad Charkhpour   +4 more
doaj   +1 more source

Navigating pregnancy and addiction recovery: Patient perspectives on perinatal care interventions for women with opioid use disorder in Kentucky, USA

Addiction, EarlyView.
Abstract Background and aims The state of Kentucky has been heavily impacted by the ongoing opioid crisis in the United States, with high overdose mortality, high prevalence of opioid use disorder (OUD), elevated maternal mortality and incidence of Neonatal Abstinence Syndrome.
Hilary L. Surratt, Olivia A. Davis, Elizabeth O. Nelson, Hayley Durr, Karen Fawcett, Jason Joy, Brandon L. Schanbacher, Marie Vice, John A. Bauer, Wendy F. Hansen   +9 more
wiley   +1 more source

A Conditioning-Strengthened Circuit From CA1 of Dorsal Hippocampus to Basolateral Amygdala Participates in Morphine-Withdrawal Memory Retrieval

Frontiers in Neuroscience, 2020
Conditioned context-induced retrieval of drug withdrawal memory contributes to drug relapse. The basolateral amygdala (BLA) is an important brain region that is involved in conditioned context-induced retrieval of morphine withdrawal memory. However, the
Qianqian Ma, Yali Fu, Zixuan Cao, Da Shao, Jiaojiao Song, Huan Sheng, Li Yang, Dongyang Cui, Ming Chen, Fei Zhao, Fei Zhao, Min-Hua Luo, Min-Hua Luo, Bin Lai, Ping Zheng   +14 more
doaj   +1 more source

Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]

, 2016
Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M., Kraft, Walter K., Stover, Megan W.   +2 more
core   +2 more sources

Rare but relevant: Ibogaine and cardiovascular complications—prolonged QT interval and ventricular arrhythmias

Addiction, EarlyView.
Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley   +1 more source

Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

Addiction, EarlyView.
Abstract Background and aims Evidence regarding the impacts of supervised drug consumption services (SDC) remains mixed, and few evaluations have used individual‐level, linkable health data to examine service withdrawal. In September 2024, the Red Deer overdose prevention site (OPS) in Alberta, Canada, was scheduled for closure, with operations ceasing
Nathaniel Day, Kym Kaufmann, Daniel John Alexander Devoe, Vanja Grubac, Alessia DiMarzo, Haisa Osmanli, Vanessa Norton, Shelly Vik, Nickie Mathew, Robert Lawrence Tanguay, Anees Bahji   +10 more
wiley   +1 more source

Protective Effect of Exercise on Liver Oxidative Stress, Inflammation and Histopathological Changes after Morphine Withdrawal in ‎Rats

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: The harmful effects of morphine on the liver after withdrawal syndrome are unclear. In this experiment, we investigated the effects of exercise on oxidative stress, liver inflammation, liver enzymes, and liver histology after ...
Ebrahim Abbasi, iraj salehi, Ebrahim Zarin Kalam, Kamal Ranjbar, Fatemeh Mirzaei, Alireza Komaki, Sara Soleimani Asl   +6 more
doaj  

Current evidence for a modulation of low back pain by human genetic variants [PDF]

, 2009
The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration
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core   +1 more source

Factors associated with readmission to residential treatment among clients transitioned from detoxification services in Alberta, Canada

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Readmission to residential treatment increases healthcare costs, strains publicly funded systems, and may not adequately meet clients' needs. This study examined rates and predictors of readmission to residential treatment among clients transitioned from detoxification services.
Abreham Mekonnen
wiley   +1 more source