Results 81 to 90 of about 26,051 (190)

Morphine Withdrawal-Induced Hyperalgesia in Models of Acute and Extended Withdrawal Is Attenuated by l-Tetrahydropalmatine. [PDF]

Int J Mol Sci, 2023
Oleinichenko D, Ahn S, Song R, Snutch TP, Phillips AG.   +4 more
europepmc   +1 more source

The Effect of Ethanol Extract of Aerial Parts of the Mentha piperita in the Acquisition, Tolerance Expression and Dependence to Morphine in Adult Male Mice

Armaghane Danesh Bimonthly Journal, 2015
Background & aim: Morphine dependence is a compulsive pattern of drug taking, resulting from the positive reinforcement of the rewarding effects of drug taking and the negative reinforcement of withdrawal syndrome that accompanies the cessation of drug ...
N Khajeh, A Eidi, J Zarringhalam
doaj  

Mitigating morphine dependence and withdrawal: The role of venlafaxine and calcium channel blockers in mitochondrial damage and oxidative stress in the brain

Brain Research Bulletin
Background: The reasons for morphine dependence and withdrawal symptoms are oxidative stress and dysfunction of cell mitochondria in the brain. Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), mitigates oxidative stress, while calcium ...
Radman Amiri, Faezeh Fallah, Behnam Ghorbanzadeh, Ali Akbar Oroojan, Mohammad Amin Behmanesh, Soheila Alboghobeish   +5 more
doaj   +1 more source

The cell-permeant antioxidant D-thiol ester D-cysteine ethyl ester overcomes physical dependence to morphine in male Sprague Dawley rats

Frontiers in Pharmacology
The ability of morphine to decrease cysteine transport into neurons by inhibition of excitatory amino acid transporter 3 (EAA3) may be a key molecular mechanism underlying the acquisition of physical and psychological dependence to morphine.
Paulina M. Getsy, Gregory A. Coffee, James N. Bates, Theodore Parran, Lee Hoffer, Santhosh M. Baby, Peter M. MacFarlane, Zackery T. Knauss, Derek S. Damron, Yee-Hsee Hsieh, Jason A. Bubier, Devin Mueller, Stephen J. Lewis, Stephen J. Lewis, Stephen J. Lewis   +14 more
doaj   +1 more source

Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice. [PDF]

iScience, 2023
Zhang J, Lu Y, Jia M, Bai Y, Sun L, Dong Z, Tian W, Yin F, Wei S, Wang Y.   +9 more
europepmc   +1 more source

Loss of Astrocytic µ Opioid Receptors Exacerbates Aversion Associated with Morphine Withdrawal in Mice: Role of Mitochondrial Respiration. [PDF]

Cells, 2023
Murlanova K, Jouroukhin Y, Novototskaya-Vlasova K, Huseynov S, Pletnikova O, Morales MJ, Guan Y, Kamiya A, Bergles DE, Dietz DM, Pletnikov MV.   +10 more
europepmc   +1 more source

Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice. [PDF]

Behav Brain Res, 2023
Bedard ML, Lord JS, Perez PJ, Bravo IM, Teklezghi AT, Tarantino LM, Diering GH, McElligott ZA.   +7 more
europepmc   +1 more source

Effect of Hydro-alcoholic extract of Jasminum sambac on morphine withdrawal symptoms in rats

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: The exact mechanisms of morphine dependence and withdrawal syndrome remain unclear. Many studies have been performed to find agents with low dependency in order to decrease withdrawal symptoms. On the other hand studies have shown the
Mohammad Raman Moloudi, Hila Moqbel, Dara Dastan, Katayoon Hasanzadeh, Bijan Noori, Esmael Izadpanah   +5 more
doaj  

Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice. [PDF]

Nat Commun, 2023
Sheng H, Lei C, Yuan Y, Fu Y, Cui D, Yang L, Shao D, Cao Z, Yang H, Guo X, Chu C, Wen Y, Cai Z, Chen M, Lai B, Zheng P.   +15 more
europepmc   +1 more source

Thymol Nanopolymer Synthesis and Its Effects on Morphine Withdrawal Syndrome in Comparison With Clonidine in Rats. [PDF]

Front Behav Neurosci, 2022
Moayeri A, Mehdizadeh R, Karimi E, Aidy A, Ghaneialvar H, Abbasi N.   +5 more
europepmc   +1 more source