An Engineered Endomorphin-2 Gene for Morphine Withdrawal Syndrome. [PDF]
PLoS ONE, 2016 An optimal therapeutics to manage opioid withdrawal syndrome is desired for opioid addiction treatment. Down-regulation of endogenous endomorphin-2 (EM2) level in the central nervous system after continuous morphine exposure was observed, which suggested
Fei-Xiang Wu +6 more
doaj +5 more sources
Effect of Morphine Withdrawal Syndrome on Cerebral Ischemia [PDF]
Iranian Journal of Basic Medical Sciences, 2011 Objective(s)Opioid abuse is still remained a major mental health problem, a criminal legal issue and may cause ischemic brain changes including stroke and brain edema.
Mohammad Allahtavakoli +3 more
doaj +3 more sources
Effects of hydroalcoholic extract of Borago officinalis on naloxone-precipitated withdrawal syndrome in morphine-dependent mice [PDF]
Bangladesh Journal of Pharmacology, 2016 The aim of the present study was to investigate the effect of hydroalcoholic extract of Borago officinalis on morphine withdrawal syndrome in mice. Morphine-dependent group received morphine for nine days and then received naloxone via intraperitoneal ...
Zahra Rabiei +2 more
doaj +5 more sources
Thymol Nanopolymer Synthesis and Its Effects on Morphine Withdrawal Syndrome in Comparison With Clonidine in Rats [PDF]
Frontiers in Behavioral Neuroscience, 2022 The drug delivery system is valuable in the treatment of the disease. A nanopolymer as a thymol and Thymbra spicata release system was synthesized and its effects on morphine withdrawal syndrome in comparison with clonidine in rats were studied.
Ardeshir Moayeri +6 more
doaj +2 more sources
Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.
PLoS ONE, 2011 A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to ...
Beng-Siang Khor +3 more
doaj +3 more sources
Aloe vera Aqueous Extract Effect on Morphine Withdrawal Syndrome in Morphine-Dependent Female Rats. [PDF]
Int J High Risk Behav Addict, 2014 Aloe vera is a medicinal herb used as an anti-inflammatory and sedative agent.The current study aimed to evaluate the effect of Aloe vera aqueous extract on morphine withdrawal symptoms in morphine-dependent female rats.The current research was performed on 40 female Wista-Albino rats which were made dependent on morphine using Houshyar protocol and ...
Shahraki MR, Mirshekari H, Sabri A.
europepmc +4 more sources
Effects of Venlafaxine & Methadone Alone and in Combination with Spontaneous Morphine withdrawal Syndrome & Pain Sensation in Rats [PDF]
Basic and Clinical Neuroscience, 2015 Introduction: Methadone has been used as a drug to detoxify opioid tolerance. Naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. On the contrary, after detoxifying the opioids, spontaneous withdrawal
Meisam Fadaei-kenarsary +3 more
doaj +1 more source
Xylopic acid from Xylopia aethiopica (Annonaceae) inhibits morphine tolerance in rats [PDF]
Pharmaceutical Sciences Asia, 2022 Traditionally, Xylopia aethiopica is used to manage pain disorders such as neuralgia, colic pain, rheumatism and headache. Using animal models, this study aimed to investigate the ability of Xylopic Acid (XA), a kaurene diterpene obtained from Xylopia ...
Priscilla Kolibea Mante +7 more
doaj +1 more source
Neural mechanisms underlying morphine withdrawal in addicted patients: a review [PDF]
Reviews in Clinical Medicine, 2015 Morphine is one of the most potent alkaloid in opium, which has substantial medical uses and needs and it is the first active principle purified from herbal source. Morphine has commonly been used for relief of moderate to severe pain as it acts directly
Nima Babhadiashar +5 more
doaj +3 more sources
The effect of an incremental resistance training program on some apoptotic markers in the heart tissue of rats with morphine withdrawal syndrome [PDF]
مجله علوم پزشکی فیض (پیوسته), 2023 Background and Aim: The use of different drugs in withdrawal syndrome usually has little effectiveness and causes the person to become dependent on new substances.
Maryam Sadegh joola +2 more
doaj +2 more sources