Results 21 to 30 of about 26,218 (217)

Evaluation of the Effects of Chronic Administration of Citrus aurantium Essential Oil on the Development of Tolerance and Dependence to Morphine [PDF]

Pharmaceutical Sciences, 2019
Background: Long-term exposure to opioids may lead to physical dependence and tolerance. The purpose of this study was to investigate the effects of Citrus aurantium essential oil (CEO) on the morphine-induced tolerance and dependence.
Alireza Parvizpur, Kosar Parnian, Sama Samankan, Fatemeh Fathiazad, Mohammad Charkhpour   +4 more
doaj   +1 more source

Neonatal abstinence syndrome: Pharmacologic strategies for the mother and infant. [PDF]

, 2016
Opioid use in pregnancy has increased dramatically over the past decade. Since prenatal opioid use is associated with numerous obstetrical and neonatal complications, this now has become a major public health problem.
Davis, Jonathan M., Kraft, Walter K., Stover, Megan W.   +2 more
core   +2 more sources

Effect of testosterone on morphine withdrawal syndrome in rats

Asian Journal of Andrology, 2008
To determine whether testosterone is involved in morphine withdrawal syndrome (WS).In order to induce dependency, rats were treated with subcutaneous injection of morphine (days 1-2, 5 mg/kg; days 3-5, 7.5 mg/kg; days 6-8, 10 mg/kg), and after the last dose of morphine (day 8) WS was induced by intraperitoneal injection of naloxone (1 mg/kg).
Ali Reza Mohajjel, Nayebi, Hassan, Rezazadeh   +1 more
openaire   +2 more sources

Protective Effect of Exercise on Liver Oxidative Stress, Inflammation and Histopathological Changes after Morphine Withdrawal in ‎Rats

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: The harmful effects of morphine on the liver after withdrawal syndrome are unclear. In this experiment, we investigated the effects of exercise on oxidative stress, liver inflammation, liver enzymes, and liver histology after ...
Ebrahim Abbasi, iraj salehi, Ebrahim Zarin Kalam, Kamal Ranjbar, Fatemeh Mirzaei, Alireza Komaki, Sara Soleimani Asl   +6 more
doaj  

Evaluating the Effects of Chronic Administration of Natural Honey on the Development of Dependence on Morphine in the Male Rats [PDF]

Pharmaceutical Sciences, 2019
Background: According to the previous studies, the exact mechanism of dependence on opioids and withdrawal syndrome has not been fully understood but one of the most important mechanisms is the increase of pro-inflammatory cytokines in CNS.
Elham Fazli shojai, Moslem Najafi, Mohammad Charkhpour   +2 more
doaj   +1 more source

Gulf War Syndrome: A role for organophosphate induced plasticity of locus coeruleus neurons [PDF]

, 2011
Gulf War syndrome is a chronic multi-symptom illness that has affected about a quarter of the deployed veterans of the 1991 Gulf War. Exposure to prolonged low-level organophosphate insecticides and other toxic chemicals is now thought to be responsible.
Andrew L. Varnell, Donald C. Cooper, Jun-li Cao   +2 more
core   +3 more sources

Current evidence for a modulation of low back pain by human genetic variants [PDF]

, 2009
The manifestation of chronic back pain depends on structural, psychosocial, occupational and genetic influences. Heritability estimates for back pain range from 30% to 45%. Genetic influences are caused by genes affecting intervertebral disc degeneration
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core   +1 more source

Morphine Versus Methadone for Neonatal Opioid Withdrawal Syndrome: A Randomized Controlled Pilot Study [PDF]

BMC Pediatrics, 2021
Abstract Background Neonatal Opioid Withdrawal Syndrome (NOWS) is a significant public health issue and while millions of neonates are affected each year, an optimal pharmacologic weaning protocol has yet to be demonstrated. In this study, we compare hospital length of stay (LOS) and length of treatment (LOT) for treatment of neonatal opioid ...
Mary Beth Sutter, Hannah Watson, Nicole Yonke, Sherry Weitzen, Lawrence Leeman   +4 more
openaire   +4 more sources

Antinociceptive Activity and Effect of Methanol Extracts of Three Salvia Spp. on Withdrawal Syndrome in Mice [PDF]

Advanced Pharmaceutical Bulletin, 2013
Purpose: There are several reports about effects of Salvia spp. on CNS. The present experiment is undertaken to study effect of S. limbata, S. hypoleuca and S. macrosiphon on withdrawal syndrome in mice.
Mohammad Karami, Mohammad Mehdi Shamerani, Ebrahim Hossini, Ahmad Reza Gohari, Mohammad Ali Ebrahimzadeh, Anahita Nosrati   +5 more
doaj   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources