Results 31 to 40 of about 1,336,492 (154)

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu   +15 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli   +7 more
wiley   +1 more source

Matricaria chamomilla Extract Inhibits Both Development of Morphine Dependence and Expression of Abstinence Syndrome in Rats

open access: yesJournal of Pharmacological Sciences, 2003
The effect of Matricaria chamomilla (M. chamomilla) on the development of morphine dependence and expression of abstinence was investigated in rats.
Adel Gomaa   +3 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Effets d'un traitement chronique par la morphine sur le protéome des cellules de neuroblastome humain SH-SY5Y [PDF]

open access: yes, 2007
Afin de mieux comprendre les adaptations cellulaires induites suite à une prise chronique de morphine, une stratégie de type protéomique différentielle combinant les techniques d'électrophorèse et de spectrométrie de masse a été entreprise dans des ...
Mouledous, Lionel
core  

The effect of vitamin C on morphine self-administration in rats

open access: yesAdvanced Biomedical Research, 2014
Background: Recent studies have shown that addiction may be caused by abnormality of neurotransmission in the brain. Two neurotransmitters that involve into morphine addiction are dopamine and glutamate.
Mahboobeh Talkhooncheh   +3 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Scores of the symptoms of morphine withdrawal syndrome.

open access: yes, 2016
Scores of the symptoms of morphine withdrawal syndrome.
Renyu Liu (184348)   +6 more
core   +1 more source

Effect of the methanolic extracts of different parts of Ferula assa-foetida on naloxone-induced withdrawal behavior in morphine-dependent mice [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2017
Objective: Ferula assa-foetida, a native species in Iran, is used for treatment of several diseases particularly for neurological disorders in Iranian Traditional Medicine.
Mahnaz Khanavi   +4 more
doaj   +1 more source

Nurses' Experiences of Pain Management for Patients With Diagnosed Mental Health Conditions: A Systematic Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To synthesise the available evidence related to nurses' pain assessment and management practices for patients with diagnosed mental health conditions. Design Mixed‐methods systematic review. Data Sources Medline, CINAHL, PsycINFO, SPORTDiscus and Psychology and Behavioural Sciences Collection.
Aaron Lapuz Alejandro   +4 more
wiley   +1 more source

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