Results 31 to 40 of about 1,336,492 (154)
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu +15 more
wiley +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
The effect of Matricaria chamomilla (M. chamomilla) on the development of morphine dependence and expression of abstinence was investigated in rats.
Adel Gomaa +3 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Effets d'un traitement chronique par la morphine sur le protéome des cellules de neuroblastome humain SH-SY5Y [PDF]
Afin de mieux comprendre les adaptations cellulaires induites suite à une prise chronique de morphine, une stratégie de type protéomique différentielle combinant les techniques d'électrophorèse et de spectrométrie de masse a été entreprise dans des ...
Mouledous, Lionel
core
The effect of vitamin C on morphine self-administration in rats
Background: Recent studies have shown that addiction may be caused by abnormality of neurotransmission in the brain. Two neurotransmitters that involve into morphine addiction are dopamine and glutamate.
Mahboobeh Talkhooncheh +3 more
doaj +1 more source
Cancer pain: current practice and emerging targets
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Scores of the symptoms of morphine withdrawal syndrome.
Scores of the symptoms of morphine withdrawal syndrome.
Renyu Liu (184348) +6 more
core +1 more source
Effect of the methanolic extracts of different parts of Ferula assa-foetida on naloxone-induced withdrawal behavior in morphine-dependent mice [PDF]
Objective: Ferula assa-foetida, a native species in Iran, is used for treatment of several diseases particularly for neurological disorders in Iranian Traditional Medicine.
Mahnaz Khanavi +4 more
doaj +1 more source
ABSTRACT Aim To synthesise the available evidence related to nurses' pain assessment and management practices for patients with diagnosed mental health conditions. Design Mixed‐methods systematic review. Data Sources Medline, CINAHL, PsycINFO, SPORTDiscus and Psychology and Behavioural Sciences Collection.
Aaron Lapuz Alejandro +4 more
wiley +1 more source

