Results 101 to 110 of about 44,228 (262)
Beyond the Simple Copper(II) Coordination Chemistry with Quinaldinate and Secondary Amines
Copper(II) acetate has reacted in methanol with quinaldinic acid (quinoline-2-carboxylic acid) to form [Cu(quin)2(CH3OH)]∙CH3OH (1) (quin− = an anionic form of the acid) with quinaldinates bound in a bidentate chelating manner.
Barbara Modec, Nina Podjed, Nina Lah
doaj +1 more source
The Diamine Cation Is Not a Chemical Example Where Density Functional Theory Fails [PDF]
In a recent communication, Weber and co-workers presented a surprising study on charge-localization effects in the N,N'-dimethylpiperazine (DMP+) diamine cation to provide a stringent test of density functional theory (DFT) methods.
Ali, Zulfikhar A. +2 more
core +3 more sources
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi +2 more
wiley +1 more source
1,2-Dimorpholinoethane-1,2-dithione
The title compound, C10H16N2O2S2, was prepared by a reaction of 4-tert-butylbenzene, morpholine and sulfur. In the crystal structure, both morpholine rings display the typical chair conformation.
doaj +1 more source
Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]
A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core +4 more sources
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno +6 more
wiley +1 more source
A bench‐stable boryl thianthrenium dication is synthesized via thianthrenation of vinyl MIDA boronate. This novel dication enables metal‐free, chemo‐, and diastereoselective late‐stage aziridination with diverse nitrogen nucleophiles. The strategic significance is further showcased by one‐pot electrochemical and asymmetric protocols and versatile ...
Veerabhadra R. Vulupala +7 more
wiley +2 more sources
Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles
A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil.
Zeinab A. Muhammad +5 more
doaj +1 more source
Genetic differentiation in Scottish populations of the pine beauty moth Panolis flammea (Lepidoptera: Noctuidae) [PDF]
Pine beauty moth, Panolis flammea (Denis & Schiffermüller), is a recent but persistent pest of lodgepole pine plantations in Scotland, but exists naturally at low levels within remnants and plantations of Scots pine.
A.D. Watt +19 more
core +2 more sources
In this article, proteolysis targeting chimeras (PROTACs) bearing a polyamine linker capable of crossing cancer cell membranes via the polyamine transport system are synthesized and evaluated. The results provide valuable insights for the design of PROTACs with enhanced cellular uptake efficiency.
Yanran Liu +6 more
wiley +1 more source

