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Pain Fluctuations in Parkinson’s Disease and Their Association with Motor and Non-Motor Fluctuations
Journal of Parkinson’s DiseaseBackground: Pain fluctuations are a characteristic phenomenon in advanced Parkinson’s disease (PD), but their temporal association with motor and non-motor symptom (NMS) fluctuations remains largely enigmatic.
Alexander Storch +5 more
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Frequency of Non-motor Symptoms in Parkinson's Patients With Motor Fluctuations [PDF]
Frontiers in Neurology, 2021 Background: Non-motor symptoms (NMS), including neuropsychiatric, sleep, autonomic, and sensory domains, are an integral aspect of the clinical presentation of Parkinson disease (PD) and affect neurocognitive functioning as well as patients' and ...
Mariana Fernandes +12 more
doaj +6 more sources
Hallucinations and parkinsonian Motor Fluctuations [PDF]
Behavioural Neurology, 1992 Thirty patients with Parkinson's disease experiencing hallucinations during long-term treatment were compared with 20 parkinsonian patients without hallucinations. No differences were found in the duration of disease, L-dopa treatment or disease severity
W. Fernandez, G. Stern, A. J. Lees
doaj +3 more sources
Motor fluctuations in Parkinson’s disease: Perceptions and treatment
Dialogues in Clinical Neuroscience & Mental Health, 2023 Background: Levodopa is the gold standard of treatment for Parkinson’s disease, but wearing off leads to motor fluctuations in most patients. Therapeutic strategy for motor fluctuation management relies heavily on physician judgement; however, real-world
Fabrizio Stocchi +2 more
doaj +3 more sources
Impact of non-motor fluctuations on QOL in patients with Parkinson’s disease [PDF]
Frontiers in Neurology, 2023 IntroductionLong-term levodopa treatment in patients with Parkinson’s disease (PwPD) often causes motor fluctuations, which are known to affect their quality of life (QOL). These motor fluctuations may be accompanied by fluctuations in non-motor symptoms.
Asako Kakimoto +5 more
doaj +2 more sources
Motor fluctuations and psychological distress in Parkinson’s disease. [PDF]
Health Psychology, 2019 Off periods in Parkinson's disease are associated with a worsening of nonmotor symptoms and acute psychological distress. The relationship between motor fluctuations and episodic distress in naturalistic settings remains unclear, particularly the role of individual psychological factors.
Bruce A. Fernie +2 more
core +7 more sources
Intestinal Decontamination Therapy for Dyskinesia and Motor Fluctuations in Parkinson's Disease [PDF]
Frontiers in Neurology, 2021 Parkinson's disease is neurodegenerative disorder with an initial robust response to levodopa. As the disease progresses, patients frequently develop dyskinesia and motor fluctuations, which are sometimes resistant to pharmacological therapy.
José Fidel Baizabal-Carvallo +2 more
doaj +2 more sources
Efficacy of Safinamide and Gender Differences During Routine Clinical Practice
Frontiers in Neurology, 2021 Background: There is increasing evidence of gender differences in the epidemiology and clinical manifestation of both motor and non-motor symptoms of Parkinson's disease (PD).
Maria T. Pellecchia +6 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2023 IntroductionEffective management and therapies for the motor complications of Parkinson’s disease (PD) require appropriate clinical evaluation. The Parkinson’s KinetiGraph™ (PKG) is a wearable biosensor system that can record the motion characteristics ...
Yan Qu +4 more
doaj +1 more source
Non-motor symptoms fluctuations in patients with Parkinson's disease at the Clinical Hospital of Salvador, Bahia [PDF]
Dementia & Neuropsychologia, 2022 . Motor fluctuations in Parkinson's disease (PD) are a frequent long-term complication. Knowledge is limited on the prevalence and incidence of non-motor symptoms (NMS) fluctuations, especially in Brazil.
Karollyne Santos Barreto +4 more
doaj +1 more source