Results 21 to 30 of about 6,457 (148)

Analysis of Motor Complication and Relative Factors in a Cohort of Chinese Patients with Parkinson’s Disease

Parkinson's Disease, 2020
Objective. Motor complications are common in Parkinson’s disease (PD). The reported occurrence of motor complications varies across regions and races.
Baihua Sun, Tao Wang, Nianying Li, Jin Qiao   +3 more
doaj   +1 more source

Automatic Spiral Analysis for Objective Assessment of Motor Symptoms in Parkinson’s Disease

Sensors, 2015
A challenge for the clinical management of advanced Parkinson’s disease (PD) patients is the emergence of fluctuations in motor performance, which represents a significant source of disability during activities of daily living of the patients. There is a
Mevludin Memedi, Aleksander Sadikov, Vida Groznik, Jure Žabkar, Martin Možina, Filip Bergquist, Anders Johansson, Dietrich Haubenberger, Dag Nyholm   +8 more
doaj   +1 more source

Fluctuation Relations for Molecular Motors [PDF]

, 2010
This review is focused on the application of specific fluctuation relations, such as the Gallavotti-Cohen relation, to ratchet models of a molecular motor. A special emphasis is placed on two-states models such as the flashing ratchet model. We derive the Gallavotti-Cohen fluctuation relation for these models and we discuss some of its implications.
Lacoste, D., Mallick, K.
openaire   +2 more sources

On the optimal degree of fluctuations in practice for motor learning [PDF]

, 2016
In human movement science, it is widely accepted that random practice generally enhances complex motor-skill learning compared to repetitive practice.
Käch, Boris, Enz, Jonas, Hossner, Ernst-Joachim   +2 more
core   +1 more source

Validation of a Portable Device for Mapping Motor and Gait Disturbances in Parkinson’s Disease

JMIR mHealth and uHealth, 2015
BackgroundPatients with severe idiopathic Parkinson’s disease experience motor fluctuations, which are often difficult to control. Accurate mapping of such motor fluctuations could help improve patients’ treatment.
Rodríguez-Molinero, Alejandro, Samà, Albert, Pérez-Martínez, David A, Pérez López, Carlos, Romagosa, Jaume, Bayés, Àngels, Sanz, Pilar, Calopa, Matilde, Gálvez-Barrón, César, de Mingo, Eva, Rodríguez Martín, Daniel, Gonzalo, Natalia, Formiga, Francesc, Cabestany, Joan, Catalá, Andreu   +14 more
doaj   +1 more source

Opicapone versus placebo in the treatment of Parkinson’s disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial

BMC Neurology, 2022
Background Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be generally well tolerated and ...
K. Ray Chaudhuri, Per Odin, Joaquim J. Ferreira, Angelo Antonini, Olivier Rascol, Mónica M. Kurtis, Alexander Storch, Kirsty Bannister, Patrício Soares-da-Silva, Raquel Costa, Diogo Magalhães, José Francisco Rocha   +11 more
doaj   +1 more source

Personality dimensions of patients can change during the course of parkinson's disease.

PLoS ONE, 2021
BackgroundStudies assessing personality dimensions by the "Temperament and Character Inventory" (TCI) have previously found an association between Parkinson's disease (PD) and lower Novelty Seeking and higher Harm Avoidance scores.
Mathilde Boussac, Christophe Arbus, Julia Dupouy, Estelle Harroch, Vanessa Rousseau, Aurélie Croiset, Fabienne Ory-Magne, Olivier Rascol, Caroline Moreau, Anne-Sophie Rolland, David Maltête, Tiphaine Rouaud, Mylène Meyer, Sophie Drapier, Bruno Giordana, Mathieu Anheim, Elodie Hainque, Béchir Jarraya, Isabelle Benatru, Nicolas Auzou, Lhaouas Belamri, Mélissa Tir, Ana-Raquel Marques, Stephane Thobois, Alexandre Eusebio, Jean Christophe Corvol, David Devos, Christine Brefel-Courbon, PREDI-STIM study group   +28 more
doaj   +1 more source

Comparison of the Results of a Parkinson's Holter Monitor With Patient Diaries, in Real Conditions of Use: A Sub-analysis of the MoMoPa-EC Clinical Trial

Frontiers in Neurology, 2022
BackgroundFor specialists in charge of Parkinson's disease (PD), one of the most time-consuming tasks of the consultations is the assessment of symptoms and motor fluctuations.
Carlos Pérez-López, Jorge Hernández-Vara, Nuria Caballol, Nuria Caballol, Àngels Bayes, Mariateresa Buongiorno, Núria Lopez-Ariztegui, Alexandre Gironell, José López-Sánchez, Juan Carlos Martínez-Castrillo, Alvarez Sauco M, Lydia López-Manzanares, Sonia Escalante-Arroyo, David A. Pérez-Martínez, Alejandro Rodríguez-Molinero, The MoMoPa-EC Research Group   +15 more
doaj   +1 more source

Validation of 24-hour ambulatory gait assessment in Parkinson's disease with simultaneous video observation

BioMedical Engineering OnLine, 2011
Background Parkinson's disease (PD) is a neurodegenerative disorder resulting in motor disturbances that can impact normal gait. Although PD initially responds well to pharmacological treatment, as the disease progresses efficacy often fluctuates over ...
Dilda Valentina, Moore Steven T, Hakim Bandar, MacDougall Hamish G   +3 more
doaj   +1 more source

Genomic Analysis Identifies New Loci Associated With Motor Complications in Parkinson's Disease

Frontiers in Neurology, 2020
Background: Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by a clinical symptomatology involving both motor and non-motor symptoms.
Ho-Sung Ryu, Kye Won Park, Nari Choi, Jinhee Kim, Young-Min Park, Sungyang Jo, Mi-Jung Kim, Young Jin Kim, Juyeon Kim, Kiju Kim, Seong-Beom Koh, Sun Ju Chung   +11 more
doaj   +1 more source