Results 31 to 40 of about 6,457 (148)

The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II

Frontiers in Neurology, 2021
Introduction: Opicapone (OPC) was efficacious in reducing OFF-time in two pivotal trials in patients with Parkinson's disease (PD) and end-of-dose motor fluctuations (BIPARK-I and -II).
José-Francisco Rocha, Georg Ebersbach, Andrew Lees, Eduardo Tolosa, Joaquim J. Ferreira, Werner Poewe, Olivier Rascol, Fabrizio Stocchi, Angelo Antonini, Diogo Magalhães, Helena Gama, Patrício Soares-da-Silva   +11 more
doaj   +1 more source

Assessment of Nonmotor Fluctuations Using a Diary in Advanced Parkinson’s disease

Journal of Parkinson’s Disease, 2016
Background: Since previous studies aimed to study nonmotor symptom (NMS) fluctuations in direct conjunction with motor oscillations, there are no data available on the temporal context of NMS fluctuations and motor oscillations in advanced Parkinson’s ...
Christiana Ossig, Daniel Sippel, Mareike Fauser, Florin Gandor, Wolfgang H. Jost, Georg Ebersbach, Alexander Storch   +6 more
doaj   +1 more source

Comparison of Parkinson’s Disease Patients’ Characteristics by Indication for Deep Brain Stimulation: Men Are More Likely to Have DBS for Tremor

Tremor and Other Hyperkinetic Movements, 2019
Background: We investigated whether the characteristics of Parkinson’s disease (PD) patients differ based on the primary indication for deep brain stimulation (DBS).
W. Alex Dalrymple, Antonia Pusso, Scott A. Sperling, Joseph L. Flanigan, Diane S. Huss, Madaline B. Harrison, W. Jeffrey Elias, Binit B. Shah, Matthew J. Barrett   +8 more
doaj   +1 more source

Effects of rhythmic auditory stimulation on motor function and balance ability in stroke: A systematic review and meta-analysis of clinical randomized controlled studies

Frontiers in Neuroscience, 2022
ObjectiveRhythmic auditory stimulation (RAS) belongs to neurologic music therapy, which has attracted clinical attention because of its efficacy in motor function after stroke.
Lei Wang, Jin-lin Peng, Wu Xiang, Yi-jie Huang, Ai-lian Chen   +4 more
doaj   +1 more source

Brownian motors: Current fluctuations and rectification efficiency [PDF]

Physical Review E, 2004
With this work we investigate an often neglected aspect of Brownian motor transport: The rôle of fluctuations of the noise-induced current and its consequences for the efficiency of rectifying noise. In doing so, we consider a Brownian inertial motor that is driven by an unbiased monochromatic, time-periodic force and thermal noise.
L. Machura, M. Kostur, P. Talkner, J. Luczka, MARCHESONI, Fabio, P. Hanggi   +5 more
openaire   +5 more sources

Home monitoring of motor fluctuations in Parkinson’s disease patients [PDF]

, 2019
In Parkinson’s disease, motor fluctuations (worsening of tremor, bradykinesia, freezing of gait, postural instability) affect up to 70% of patients within 9 years of L-dopa therapy.
Fabbri, Margherita, Rizzone, Mario Giorgio, Romagnolo, Alberto, Borzì, Luigi, Artusi, Carlo Alberto, Lopiano, Leonardo, Zibetti, Maurizio, Varrecchia, Marilena, Olmo, Gabriella   +8 more
core   +1 more source

Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson’s Disease: Observations and Dilemmas after 10 Years of Real-Life Experience

Pharmaceutics, 2022
Advanced Parkinson’s disease (APD) cannot be treated efficiently using the classical medications however, in recent decades invasive therapeutical methods were implemented and confirmed as effective. One of these methods makes it possible to continue the
József Attila Szász, Viorelia Adelina Constantin, Károly Orbán-Kis, Ligia Ariana Bancu, Simona Maria Bataga, Marius Ciorba, Előd Nagy, Mircea Radu Neagoe, István Mihály, Róbert Máté Szász, Krisztina Kelemen, Mihaela Simu, Szabolcs Szatmári   +12 more
doaj   +1 more source

Inconsistency in serial choice decision and motor reaction times dissociate in younger and older adults

, 2004
Intraindividual variability (inconsistency) in reaction time (RT) latencies was investigated in a group of younger (M = 25.46 years) and older (M = 69.29 years) men.
MacDonald, SWS, Hultsch, DF, Bunce, D
core   +1 more source

Extreme levels of noise constitute a key neuromuscular deficit in the elderly

, 2012
Fluctuations during isometric force production tasks occur due to the inability of musculature to generate purely constant submaximal forces and are considered to be an estimation of neuromuscular noise.
William R Taylor, Navrag B. Singh, Singh Navrag B., Singh, Navrag; id_orcid, Singh, Navrag B., Niklas König, Markus O Heller, Adamantios Arampatzis, Heller Markus O., Taylor, William R., König Niklas, König, Niklas, Taylor William R., William R. Taylor, Markus O. Heller, Arampatzis, Adamantios, Taylor, William R.; id_orcid, Arampatzis Adamantios, Heller, Markus O., Navrag B Singh   +19 more
core   +1 more source

Relation between motor unit / muscle activity and fine motor performance

Journal of Physical Fitness and Sports Medicine, 2014
Human movement is a consequence of joint torque or muscle force produced by muscle or muscle groups. Therefore, motor performance in human movements can be determined by the accuracy of joint torque or force produced by muscle/muscle groups.
Yasuhide Yoshitake
doaj   +1 more source