Results 31 to 40 of about 77,969 (254)

Validation of 24-hour ambulatory gait assessment in Parkinson's disease with simultaneous video observation

BioMedical Engineering OnLine, 2011
Background Parkinson's disease (PD) is a neurodegenerative disorder resulting in motor disturbances that can impact normal gait. Although PD initially responds well to pharmacological treatment, as the disease progresses efficacy often fluctuates over ...
Dilda Valentina, Moore Steven T, Hakim Bandar, MacDougall Hamish G   +3 more
doaj   +1 more source

Genomic Analysis Identifies New Loci Associated With Motor Complications in Parkinson's Disease

Frontiers in Neurology, 2020
Background: Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by a clinical symptomatology involving both motor and non-motor symptoms.
Ho-Sung Ryu, Kye Won Park, Nari Choi, Jinhee Kim, Young-Min Park, Sungyang Jo, Mi-Jung Kim, Young Jin Kim, Juyeon Kim, Kiju Kim, Seong-Beom Koh, Sun Ju Chung   +11 more
doaj   +1 more source

The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II

Frontiers in Neurology, 2021
Introduction: Opicapone (OPC) was efficacious in reducing OFF-time in two pivotal trials in patients with Parkinson's disease (PD) and end-of-dose motor fluctuations (BIPARK-I and -II).
José-Francisco Rocha, Georg Ebersbach, Andrew Lees, Eduardo Tolosa, Joaquim J. Ferreira, Werner Poewe, Olivier Rascol, Fabrizio Stocchi, Angelo Antonini, Diogo Magalhães, Helena Gama, Patrício Soares-da-Silva   +11 more
doaj   +1 more source

Assessment of Nonmotor Fluctuations Using a Diary in Advanced Parkinson’s disease

Journal of Parkinson’s Disease, 2016
Background: Since previous studies aimed to study nonmotor symptom (NMS) fluctuations in direct conjunction with motor oscillations, there are no data available on the temporal context of NMS fluctuations and motor oscillations in advanced Parkinson’s ...
Christiana Ossig, Daniel Sippel, Mareike Fauser, Florin Gandor, Wolfgang H. Jost, Georg Ebersbach, Alexander Storch   +6 more
doaj   +1 more source

Comparison of Parkinson’s Disease Patients’ Characteristics by Indication for Deep Brain Stimulation: Men Are More Likely to Have DBS for Tremor

Tremor and Other Hyperkinetic Movements, 2019
Background: We investigated whether the characteristics of Parkinson’s disease (PD) patients differ based on the primary indication for deep brain stimulation (DBS).
W. Alex Dalrymple, Antonia Pusso, Scott A. Sperling, Joseph L. Flanigan, Diane S. Huss, Madaline B. Harrison, W. Jeffrey Elias, Binit B. Shah, Matthew J. Barrett   +8 more
doaj   +1 more source

Effects of rhythmic auditory stimulation on motor function and balance ability in stroke: A systematic review and meta-analysis of clinical randomized controlled studies

Frontiers in Neuroscience, 2022
ObjectiveRhythmic auditory stimulation (RAS) belongs to neurologic music therapy, which has attracted clinical attention because of its efficacy in motor function after stroke.
Lei Wang, Jin-lin Peng, Wu Xiang, Yi-jie Huang, Ai-lian Chen   +4 more
doaj   +1 more source

Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson’s Disease: Observations and Dilemmas after 10 Years of Real-Life Experience

Pharmaceutics, 2022
Advanced Parkinson’s disease (APD) cannot be treated efficiently using the classical medications however, in recent decades invasive therapeutical methods were implemented and confirmed as effective. One of these methods makes it possible to continue the
József Attila Szász, Viorelia Adelina Constantin, Károly Orbán-Kis, Ligia Ariana Bancu, Simona Maria Bataga, Marius Ciorba, Előd Nagy, Mircea Radu Neagoe, István Mihály, Róbert Máté Szász, Krisztina Kelemen, Mihaela Simu, Szabolcs Szatmári   +12 more
doaj   +1 more source

Brownian motors: Current fluctuations and rectification efficiency [PDF]

Physical Review E, 2004
With this work we investigate an often neglected aspect of Brownian motor transport: The rôle of fluctuations of the noise-induced current and its consequences for the efficiency of rectifying noise. In doing so, we consider a Brownian inertial motor that is driven by an unbiased monochromatic, time-periodic force and thermal noise.
L. Machura, M. Kostur, P. Talkner, J. Luczka, MARCHESONI, Fabio, P. Hanggi   +5 more
openaire   +5 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source