Results 51 to 60 of about 6,457 (148)
Parkinson's disease is neurodegenerative disorder with an initial robust response to levodopa. As the disease progresses, patients frequently develop dyskinesia and motor fluctuations, which are sometimes resistant to pharmacological therapy.
Robert Fekete (11416514) +2 more
core +1 more source
BackgroundSubcutaneous foslevodopa/foscarbidopa (LDp/CDp) has expanded the treatment options in advanced Parkinson’s disease (aPD). However, the most appropriate therapeutic setting for therapy implementation is not clear.ObjectiveTo present a concept ...
Alina Jander +5 more
doaj +1 more source
Unraveling the Relationship between Motor Symptoms, Affective States and Contextual Factors in Parkinson's Disease: A Feasibility Study of the Experience Sampling Method. [PDF]
BACKGROUND:In Parkinson's disease (PD), the complex relationship between motor symptoms, affective states, and contextual factors remains to be elucidated. The Experience Sampling Method provides (ESM) a novel approach to this issue.
Martijn P G Broen +5 more
doaj +1 more source
Parkinson's disease is neurodegenerative disorder with an initial robust response to levodopa. As the disease progresses, patients frequently develop dyskinesia and motor fluctuations, which are sometimes resistant to pharmacological therapy.
Robert Fekete (11416514) +2 more
core +1 more source
Background/Objectives: Continuous subcutaneous foslevodopa/foscarbidopa infusion (CSFLI) improves motor fluctuations in advanced Parkinson’s disease (PD), but some patients continue to experience residual motor and non-motor fluctuations despite ...
Paolo Solla +8 more
doaj +1 more source
OBJECTIVE: To test the efficacy, tolerance, and safety of low-dose oral estrogen in postmenopausal women with PD associated with motor fluctuations. BACKGROUND: Motor fluctuations in PD may be predictable or unpredictable, and eventually affect most ...
Ho, SL, Tsang, KL, Lo, SK
core +1 more source
Parkinson's disease is neurodegenerative disorder with an initial robust response to levodopa. As the disease progresses, patients frequently develop dyskinesia and motor fluctuations, which are sometimes resistant to pharmacological therapy.
Robert Fekete (11416514) +2 more
core +1 more source
The wearing-off phenomenon is common in patients with Parkinson's disease. Motor and non-motor symptoms can fluctuate in relation to the “on/off” periods.
Mayela Rodríguez-Violante +5 more
doaj +1 more source
Fluctuation relations and fluctuation-response for molecular motors [PDF]
Fluctuation relations are a set of remarkable relations obeyed by a large class of systems and arbitrarily far from equilibrium. It is interesting to discuss the implications of these relations for molecular motors, which are chemically driven enzymes.
VERLEY, Gatien, Lacoste, D.
openaire
Novel pattern of levodopa-related motor fluctuations: 'paradoxical'on
Generally, motor functions of Parkinson disease (PD) patients become worse as levodopa wears off. Recently, we encountered four PD patients who reported that their motor functions get better after levodopa wears off.
Jeon, Beom S +3 more
core +1 more source

