Results 61 to 70 of about 6,457 (148)

Impact of motor fluctuations on real-life gait in Parkinson’s patients [PDF]

, 2018
Background people with PD (PWP) have an increased risk of becoming inactive. Wearable sensors can provide insights into daily physical activity and walking patterns.
Daeschler, M., Bastiaan R. Bloem, Faber, M.J., Hahn, T., Boroojerdi, Babak, Max A. Little, Terricabras, Dolors, Hahn, Tim, Faber, Marjan J., Evers, L.J.W., De Vries, Nienke M., Boroojerdi, B., Bloem, Bastiaan R., Bloem, B.R., Vries, N.M. de, Little, Max A, Daeschler, Margaret, Dolors Terricabras, Margaret Daeschler, Silva de Lima, Ana Lígia, Babak Boroojerdi, Tim Hahn, Marjan J. Faber, Nienke M. de Vries, Evers, Luc J.W., Silva de Lima, A.L., Ana Lígia Silva de Lima, Luc J.W. Evers   +27 more
core   +1 more source

Correction of non-motor vegetative fluctuations with Parkinson`s disease based on levodopa treatment [PDF]

, 2014
The influence of dopamin receptors agonists in the transdermal and oral forms of drugs and amantadine for non-motor autonomic fluctuations of ptients with different duration of the disease during the treatment of Parkinson`s in a stable dose of levodopa ...
Таряник, Катерина Анатоліївна, Tarianyk, K. A.   +1 more
core   +1 more source

Motor fluctuations in Parkinson's disease: pathogenetic and therapeutic studies.

, 1987
The response to continuous intravenous infusion of levodopa was evaluated in 23 patients with Parkinson's disease complicated by motor fluctuations.
FABBRINI, Giovanni, T. N. Chase, M. M. Mouradian, J. L. Juncos   +3 more
core   +1 more source

The hidden sister of motor fluctuations in Parkinson's disease: A review on nonmotor fluctuations

Movement Disorders, 2016
ABSTRACT Only a few years after the introduction of levodopa, the first descriptions of motor fluctuations and dyskinesia related to dopaminergic therapy appeared. In PD, attention turned to their management, that had dampened the euphoria of the “levodopa miracle.” It soon became clear that neuropsychiatric ...
Martinez-Fernandez, Raul, Schmitt, Emmanuelle, Martinez-Martin, Pablo, Krack, Paul   +3 more
openaire   +5 more sources

Quantitative assessment of non-motor fluctuations in Parkinson's disease using the Non-Motor Symptoms Scale (NMSS)

, 2015
Data on frequency, severity and correlations of NMS with motor complications are only available for a limited number of NMS. The NMS Scale (NMSS) is a validated tool to assess a broad range of NMS, which has not been used in NMS fluctuations. We assessed
Schneider, Christine B., Storch, Alexander, Martinez-Martin, Pablo, Jost, Wolfgang, Klingelhöfer, Lisa, Fuchs, Gerd. A., Koch, Rainer, Ebersbach, Georg, ?, ?, Fuchs, Gerd, Klingelhoefer, Lisa, Jost, Wolfgang H., Nomoflu-Pd Study Group, Study Group, Chaudhuri, K. Ray, Odin, Per, Reichmann, Heinz, NoMoFlu-PD, [Study group]   +16 more
core   +1 more source

Safinamide in the management of patients with Parkinson’s disease not stabilized on levodopa: a review of the current clinical evidence

Therapeutics and Clinical Risk Management, 2018
Sagari Bette, Danielle S Shpiner, Carlos Singer, Henry Moore Department of Neurology, Division of Parkinson’s Disease and Movement Disorders, University of Miami – Miller School of Medicine, Miami, FL, USA Abstract: Safinamide (Xadago®)
Bette S, Shpiner DS, Singer C, Moore H
doaj  

Improvement in Motor Consistency and Stability with Foslevodopa/Foscarbidopa in Advanced Parkinson’s Disease: Post Hoc Analysis of Two Phase 3 Clinical Trials

Neurology and Therapy
Introduction People with advanced Parkinson’s disease (aPD) frequently experience unpredictable “Off” time and debilitating motor fluctuations. Foslevodopa/foscarbidopa (LDp/CDp), a levodopa/carbidopa (LD/CD) prodrug, is delivered as a 24-h continuous ...
Rajesh Pahwa, Jason Aldred, Michael J. Soileau, David G. Standaert, Victor S. C. Fung, Thomas Kimber, Irene A. Malaty, Diego Santos-García, Camille Carroll, Tove Henriksen, Ashwini Parab, Connie H. Yan, Maurizio F. Facheris, Amy Spiegel, Linda Harmer, Jorge Zamudio, K. Ray Chaudhuri   +16 more
doaj   +1 more source

The impact of exchange rate fluctuations on profit margins: The UK car market, 1971-2002 [PDF]

We investigate the impact on profit margins of exchange rate fluctuations in order to examine optimal pricing policy by source countries in the UK car market.
James Walker, Francisco Requena-Silvente
core  

Measuring Gait Quality in Parkinson’s Disease through Real-Time Gait Phase Recognition

Sensors, 2018
Monitoring gait quality in daily activities through wearable sensors has the potential to improve medical assessment in Parkinson’s Disease (PD). In this study, four gait partitioning methods, two based on thresholds and two based on a machine learning ...
Ilaria Mileti, Marco Germanotta, Enrica Di Sipio, Isabella Imbimbo, Alessandra Pacilli, Carmen Erra, Martina Petracca, Stefano Rossi, Zaccaria Del Prete, Anna Rita Bentivoglio, Luca Padua, Eduardo Palermo   +11 more
doaj   +1 more source

Early start of opicapone in Parkinson’s disease: evidence from a pooled analysis of phase 3 trials for sustained benefit in patients with recent onset of motor fluctuations

Frontiers in Neurology
BackgroundLevodopa is the mainstay of Parkinson’s disease (PD) therapy, but its long-term use is often complicated by the development of motor fluctuations.
Joaquim J. Ferreira, Joaquim J. Ferreira, Fabrizio Stocchi, Fabrizio Stocchi, Angelo Antonini, Angelo Antonini, Olivier Rascol, Olivier Rascol, Georg Ebersbach, Jaime Kulisevsky, Jaime Kulisevsky, Jaime Kulisevsky, Miguel M. Fonseca, Daniel Ramos, José Francisco Rocha, Helena C. Brigas, Joerg Holenz, Werner Poewe   +17 more
doaj   +1 more source