Results 71 to 80 of about 6,457 (148)
Translational Neurodegeneration, 2017 Background Subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment for Parkinson’s disease (PD), the predictive effect of levodopa responsiveness on surgical outcomes was confirmed by some studies, however there were different ...
Xin-Ling Su +5 more
doaj +1 more source
, 2005 and Roger M. Enoka. Frequency modulation of motor unit discharge has task-dependent effects on fluctuations in motor output. J Neurophysiol 94: 2878–2887, 2005. First published July 6, 2005; doi:10.1152/jn.00390.2005.
François G. Meyer +4 more
core
Effect of Voltage Fluctuations on Induction Motor Currents
One of the types of power quality disturbances met in a power system is voltage fluctuations. Cyclic voltage fluctuations are interconnected with the presence of subharmonics and interharmonics – that is components of frequency less than the fundamental ...
Marcin Pepliński, Piotr Gnaciński
core +1 more source
Controlled release levodopa-carbidopa (CR-5) in the management of parkinsonian motor fluctuations.
, 1987 Parkinsonian patients receiving long-term levodopa-carbidopa (Sinemet) therapy often develop fluctuations in motor performance. Although maintenance of stable levels of plasma levodopa by means of its continuous intravenous infusion diminishes these ...
FABBRINI, Giovanni +4 more
core +1 more source
, 1998 In animal models of Parkinson's disease (PD), glutamate antagonists diminish levodopa (LD)-associated motor fluctuations and dyskinesias. We sought to investigate if these preclinical observations can be extended to the human disease, by evaluating the ...
Blanchet, P. J. +4 more
core +1 more source
Motor fluctuations in Parkinson's disease: central pathophysiological mechanisms, Part II.
, 1988 The contribution of central pharmacodynamic mechanisms to the pathogenesis of motor fluctuations in advanced Parkinson's disease was studied in 29 patients by evaluating their acute response to intravenously injected levodopa.
J. J. Bartko +5 more
core +1 more source
Scientific ReportsMovement deterioration is the hallmark of Parkinson’s disease (PD), characterized by levodopa-induced motor-fluctuations (i.e., symptoms’ variability related to the medication cycle) in advanced stages.
Tsviya Fay-Karmon +6 more
doaj +1 more source
Timing and Kinetics of Nonmotor Fluctuations in Advanced Parkinson’s Disease
Journal of Parkinson’s Disease, 2017 Background: Nonmotor symptoms (NMS) are known to fluctuate together with motor oscillations in advanced PD, but their timing and kinetics remains enigmatic. Objective: To evaluate timing and kinetics of NMS fluctuations.
Christiana Ossig +6 more
doaj +1 more source
Nonthermal fluctuations accelerate biomolecular motors
Biophysical ReviewsAbstractIntracellular transport is essential for maintaining cellular function. This process is driven by different mechanisms in prokaryotic and eukaryotic cells. In small prokaryotic cells, diffusion is the primary means of transport, while larger eukaryotic cells also rely on active transport by molecular motors such as kinesin and dynein. Recently,
openaire +3 more sources
PharmaceuticsLevodopa–entacapone–carbidopa intestinal gel infusion is a relatively new treatment option for advanced Parkinson’s disease. We aimed to describe and analyze the characteristics of de novo levodopa–entacapone–carbidopa intestinal gel therapy in 20 ...
Szabolcs Szatmári +13 more
doaj +1 more source