Results 11 to 20 of about 6,457 (148)

Comparative Efficacy and Safety of Dopamine Agonists in Advanced Parkinson's Disease With Motor Fluctuations: A Systematic Review and Network Meta-Analysis of Double-Blind Randomized Controlled Trials

open access: yesFrontiers in Neuroscience, 2021
Background: Movement fluctuations are the main complication of Parkinson's disease (PD) patients receiving long-term levodopa (L-dopa) treatment. We compared and ranked the efficacy and safety of dopamine agonists (DAs) with regard to motor fluctuations ...
Xinglin Ruan   +13 more
doaj   +1 more source

Could New Generations of Sensors Reshape the Management of Parkinson’s Disease?

open access: yesClinical and Translational Neuroscience, 2021
Parkinson's disease (PD) is a chronic neurologic disease that has a great impact on the patient’s quality of life. The natural course of the disease is characterized by an insidious onset of symptoms, such as rest tremor, shuffling gait, bradykinesia ...
Oleg S. Levin   +3 more
doaj   +1 more source

The Management of Parkinson’s Disease: An Overview of the Current Advancements in Drug Delivery Systems

open access: yesPharmaceutics, 2023
Parkinson’s disease (PD) has significantly affected a large proportion of the elderly population worldwide. According to the World Health Organization, approximately 8.5 million people worldwide are living with PD.
Deepa D. Nakmode   +3 more
doaj   +1 more source

Characterisation of non‐motor fluctuations using the Movement Disorder Society Non‐Motor Rating Scale [PDF]

open access: yes, 2022
BACKGROUND: Non-motor fluctuations (NMF) in people with Parkinson's disease (PwP) are clinically important yet understudied. OBJECTIVE: To study NMF in PwP using both the Movement Disorder Society Non-Motor Rating Scale (MDS-NMS) NMF subscale and ...
Martinez-Martin, P.   +25 more
core   +1 more source

What can we learn from the effect of trihexyphenidyl on motor fluctuations during continuous levodopa-carbidopa intestinal gel infusion (LCIG)? – First documented case

open access: yesClinical Parkinsonism & Related Disorders, 2020
Motor fluctuations can be seen even during treatment with continuous levodopa-carbidopa intestinal gel infusion (LCIG). We report on a middle-aged man with advanced Parkinson's disease (PD) on LCIG in which motor fluctuations have been improved with an ...
Shin-ichiro Kubo   +4 more
doaj   +1 more source

Fluctuations, responses and energetics of molecular motors [PDF]

open access: yesMathematical Biosciences, 2007
22 pages, 3 figures, submitted to Mathematical ...
Harada, Takahiro, Sasa, Shin-Ichi
openaire   +4 more sources

Rescue Levodopa/Carbidopa Intestinal Gel for Secondary Deep Brain Stimulation Failure [PDF]

open access: yesJournal of Movement Disorders, 2020
Objective The long-term efficacy of deep brain stimulation (DBS) for motor fluctuations in advanced Parkinson’s disease (PD) has been well established; however, motor fluctuations may recur over time despite multiple adjustments of DBS settings and ...
Juan Miguel Pilar Bautista   +11 more
doaj   +1 more source

Unraveling the fluctuations of animal motor activity [PDF]

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2009
Human and animal behavior exhibits power law correlations whose origin is controversial. In this work, the spontaneous motion of laboratory rodents was recorded during several days. It is found that animal motion is scale-free and that the scaling is introduced by the inactivity pauses both by its length as well as by its specific ordering. Furthermore,
Anteneodo, C., Chialvo, D. R.
openaire   +3 more sources

How Wearable Sensors Can Support Parkinson's Disease Diagnosis and Treatment: A Systematic Review

open access: yesFrontiers in Neuroscience, 2017
Background: Parkinson's disease (PD) is a common and disabling pathology that is characterized by both motor and non-motor symptoms and affects millions of people worldwide. The disease significantly affects quality of life of those affected.
Erika Rovini   +2 more
doaj   +1 more source

Single-Phase Induction Motor Under Voltage Fluctuations

open access: yesScientific Journal of Gdynia Maritime University, 2022
Some of the most common power quality disturbances are voltage fluctuations. They are interconnected with the presence of voltage subharmonics and interharmonics.
Marcin Pepliński   +2 more
doaj   +1 more source

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