Results 11 to 20 of about 275,912 (292)

Efficacy of Safinamide and Gender Differences During Routine Clinical Practice

Frontiers in Neurology, 2021
Background: There is increasing evidence of gender differences in the epidemiology and clinical manifestation of both motor and non-motor symptoms of Parkinson's disease (PD).
Maria T. Pellecchia, Marina Picillo, Maria C. Russillo, Maria F. De Pandis, Erminio Bonizzoni, Ivan Marjanovic, Carlo Cattaneo   +6 more
doaj   +1 more source

Identification and quantitative assessment of motor complications in Parkinson’s disease using the Parkinson’s KinetiGraph™

Frontiers in Aging Neuroscience, 2023
IntroductionEffective management and therapies for the motor complications of Parkinson’s disease (PD) require appropriate clinical evaluation. The Parkinson’s KinetiGraph™ (PKG) is a wearable biosensor system that can record the motion characteristics ...
Yan Qu, Tingting Zhang, Yunyan Duo, Liling Chen, Xiaohong Li   +4 more
doaj   +1 more source

Non-motor symptoms fluctuations in patients with Parkinson's disease at the Clinical Hospital of Salvador, Bahia [PDF]

Dementia & Neuropsychologia, 2022
. Motor fluctuations in Parkinson's disease (PD) are a frequent long-term complication. Knowledge is limited on the prevalence and incidence of non-motor symptoms (NMS) fluctuations, especially in Brazil.
Karollyne Santos Barreto, Jamary Oliveira Filho, Luana Dias Reis, Tayane Guimarães Ribeiro, Roberta Borges Gomes Kauark   +4 more
doaj   +1 more source

Comparative Efficacy and Safety of Dopamine Agonists in Advanced Parkinson's Disease With Motor Fluctuations: A Systematic Review and Network Meta-Analysis of Double-Blind Randomized Controlled Trials

Frontiers in Neuroscience, 2021
Background: Movement fluctuations are the main complication of Parkinson's disease (PD) patients receiving long-term levodopa (L-dopa) treatment. We compared and ranked the efficacy and safety of dopamine agonists (DAs) with regard to motor fluctuations ...
Xinglin Ruan, Fabin Lin, Fabin Lin, Dihang Wu, Dihang Wu, Lina Chen, Huidan Weng, Jiao Yu, Yingqing Wang, Ying Chen, Xiaochun Chen, Qinyong Ye, Fangang Meng, Guoen Cai   +13 more
doaj   +1 more source

Could New Generations of Sensors Reshape the Management of Parkinson’s Disease?

Clinical and Translational Neuroscience, 2021
Parkinson's disease (PD) is a chronic neurologic disease that has a great impact on the patient’s quality of life. The natural course of the disease is characterized by an insidious onset of symptoms, such as rest tremor, shuffling gait, bradykinesia ...
Oleg S. Levin, Olga V. Iakovleva, Irina I. Coloman, Anastasia V. Kuzmina   +3 more
doaj   +1 more source

The Management of Parkinson’s Disease: An Overview of the Current Advancements in Drug Delivery Systems

Pharmaceutics, 2023
Parkinson’s disease (PD) has significantly affected a large proportion of the elderly population worldwide. According to the World Health Organization, approximately 8.5 million people worldwide are living with PD.
Deepa D. Nakmode, Candace M. Day, Yunmei Song, Sanjay Garg   +3 more
doaj   +1 more source

Acute Spinal Cord Injury: Correlations and Causal Relations Between Intraspinal Pressure, Spinal Cord Perfusion Pressure, Lactate-to-Pyruvate Ratio, and Limb Power. [PDF]

, 2021
BACKGROUND/OBJECTIVE: We have recently developed monitoring from the injury site in patients with acute, severe traumatic spinal cord injuries to facilitate their management in the intensive care unit.
Hogg, FRA, Kearney, S, Papadopoulos, MC, Saadoun, S, Zoumprouli, A   +4 more
core   +1 more source

What can we learn from the effect of trihexyphenidyl on motor fluctuations during continuous levodopa-carbidopa intestinal gel infusion (LCIG)? – First documented case

Clinical Parkinsonism & Related Disorders, 2020
Motor fluctuations can be seen even during treatment with continuous levodopa-carbidopa intestinal gel infusion (LCIG). We report on a middle-aged man with advanced Parkinson's disease (PD) on LCIG in which motor fluctuations have been improved with an ...
Shin-ichiro Kubo, Ken Nakamura, Yoshimasa Tada, Nobuyuki Kashio, Shinya Yamashita   +4 more
doaj   +1 more source

Rescue Levodopa/Carbidopa Intestinal Gel for Secondary Deep Brain Stimulation Failure [PDF]

Journal of Movement Disorders, 2020
Objective The long-term efficacy of deep brain stimulation (DBS) for motor fluctuations in advanced Parkinson’s disease (PD) has been well established; however, motor fluctuations may recur over time despite multiple adjustments of DBS settings and ...
Juan Miguel Pilar Bautista, Genko Oyama, Maierdanjiang Nuermaimaiti, Satoko Sekimoto, Fuyuko Sasaki, Taku Hatano, Kenya Nishioka, Masanobu Ito, Atsushi Umemura, Yuji Ishibashi, Yasushi Shimo, Nobutaka Hattori   +11 more
doaj   +1 more source

Fluctuating-friction molecular motors [PDF]

Journal of Physics: Condensed Matter, 2001
to be published in J. Physics Condensed Matter (http://www.iop.org/Journals/JPhysCM)
MARRUCCI, LORENZO, PAPARO D, KREUZER M.
openaire   +3 more sources