Results 11 to 20 of about 77,969 (254)
Motor fluctuations in Parkinson’s disease: Perceptions and treatment
Dialogues in Clinical Neuroscience & Mental Health, 2023 Background: Levodopa is the gold standard of treatment for Parkinson’s disease, but wearing off leads to motor fluctuations in most patients. Therapeutic strategy for motor fluctuation management relies heavily on physician judgement; however, real-world
Fabrizio Stocchi +2 more
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Efficacy of Safinamide and Gender Differences During Routine Clinical Practice
Frontiers in Neurology, 2021 Background: There is increasing evidence of gender differences in the epidemiology and clinical manifestation of both motor and non-motor symptoms of Parkinson's disease (PD).
Maria T. Pellecchia +6 more
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Frontiers in Aging Neuroscience, 2023 IntroductionEffective management and therapies for the motor complications of Parkinson’s disease (PD) require appropriate clinical evaluation. The Parkinson’s KinetiGraph™ (PKG) is a wearable biosensor system that can record the motion characteristics ...
Yan Qu +4 more
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Frontiers in Neuroscience, 2021 Background: Movement fluctuations are the main complication of Parkinson's disease (PD) patients receiving long-term levodopa (L-dopa) treatment. We compared and ranked the efficacy and safety of dopamine agonists (DAs) with regard to motor fluctuations ...
Xinglin Ruan +13 more
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Non-motor symptoms fluctuations in patients with Parkinson's disease at the Clinical Hospital of Salvador, Bahia [PDF]
Dementia & Neuropsychologia, 2022 . Motor fluctuations in Parkinson's disease (PD) are a frequent long-term complication. Knowledge is limited on the prevalence and incidence of non-motor symptoms (NMS) fluctuations, especially in Brazil.
Karollyne Santos Barreto +4 more
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Could New Generations of Sensors Reshape the Management of Parkinson’s Disease?
Clinical and Translational Neuroscience, 2021 Parkinson's disease (PD) is a chronic neurologic disease that has a great impact on the patient’s quality of life. The natural course of the disease is characterized by an insidious onset of symptoms, such as rest tremor, shuffling gait, bradykinesia ...
Oleg S. Levin +3 more
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Pharmaceutics, 2023 Parkinson’s disease (PD) has significantly affected a large proportion of the elderly population worldwide. According to the World Health Organization, approximately 8.5 million people worldwide are living with PD.
Deepa D. Nakmode +3 more
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Clinical Parkinsonism & Related Disorders, 2020 Motor fluctuations can be seen even during treatment with continuous levodopa-carbidopa intestinal gel infusion (LCIG). We report on a middle-aged man with advanced Parkinson's disease (PD) on LCIG in which motor fluctuations have been improved with an ...
Shin-ichiro Kubo +4 more
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Fluctuations, responses and energetics of molecular motors [PDF]
Mathematical Biosciences, 2007 22 pages, 3 figures, submitted to Mathematical ...
Harada, Takahiro, Sasa, Shin-Ichi
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Rescue Levodopa/Carbidopa Intestinal Gel for Secondary Deep Brain Stimulation Failure [PDF]
Journal of Movement Disorders, 2020 Objective The long-term efficacy of deep brain stimulation (DBS) for motor fluctuations in advanced Parkinson’s disease (PD) has been well established; however, motor fluctuations may recur over time despite multiple adjustments of DBS settings and ...
Juan Miguel Pilar Bautista +11 more
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