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Motor Proteins. [PDF]

open access: yesCold Spring Harb Perspect Biol, 2018
Myosin motors power movements on actin filaments, whereas dynein and kinesin motors power movements on microtubules. The mechanisms of these motor proteins differ, but, in all cases, ATP hydrolysis and subsequent release of the hydrolysis products drives a cycle of interactions with the track (either an actin filament or a microtubule), resulting in ...
Sweeney HL, Holzbaur ELF.
europepmc   +4 more sources

Simulated actin reorganization mediated by motor proteins. [PDF]

open access: yesPLoS Computational Biology, 2022
Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization in many different contexts, including during directed cell migration and over ...
Maria-Veronica Ciocanel   +5 more
doaj   +2 more sources

Flagellar brake protein YcgR interacts with motor proteins MotA and FliG to regulate the flagellar rotation speed and direction [PDF]

open access: yesFrontiers in Microbiology, 2023
In E. coli and related species, flagellar brake protein YcgR responds to the elevated intracellular c-di-GMP, decreases the flagellar rotation speed, causes a CCW rotation bias, and regulates bacterial swimming. Boehm et al.
Qun Han   +11 more
doaj   +2 more sources

Structures of kinesin motor proteins [PDF]

open access: bronzeCell Motility, 2009
AbstractAlmost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X‐ray crystallography and cryoelectron microscopy 3‐
Alexander Marx   +2 more
openalex   +4 more sources

Navigation Strategies of Motor Proteins on Decorated Tracks. [PDF]

open access: yesPLoS ONE, 2015
Motor proteins display widely different stepping patterns as they move on microtubule tracks, from the deterministic linear or helical motion performed by the protein kinesin to the uncoordinated random steps made by dynein.
Zsolt Bertalan   +3 more
doaj   +2 more sources

Japan-US symposium on cytoskeletal motor proteins and their associated proteins [PDF]

open access: yesBiophysics and Physicobiology, 2021
Kumiko Hayashi, Shinsuke Niwa
doaj   +2 more sources

Engineered kinesin motor proteins amenable to small-molecule inhibition [PDF]

open access: yesNature Communications, 2016
The use of specific small molecule inhibitors can contribute to the study of kinesins' cellular functions. Here the authors develop a chemical-genetic approach to engineer kinesin motors that can be efficiently inhibited upon addition of cell-permeable ...
Martin F. Engelke   +10 more
doaj   +2 more sources

Molecular Motors–Nature’s Efficiency at Work

open access: yesReports in Advances of Physical Sciences, 2022
Nature has generated sophisticated and very efficient molecular motors, employed for nanoscale transport at the intracellular level. As a complementary tool to nanofluidics, these motors have been envisioned for nanotechnological devices.
Winfried Teizer
doaj   +1 more source

What is axoplasmic transport? Considering the role of exercise training: A mini review [PDF]

open access: yesJournal of Exercise & Organ Cross Talk, 2022
Like other cells in the body, nerve cells need many proteins and substances to maintain homeostasis. As we know, the transcription and translation of proteins and necessary cellular substances occurs in the cell nucleus.
Hasti Sherizadeh
doaj   +1 more source

Critical assessment of coiled-coil predictions based on protein structure data

open access: yesScientific Reports, 2021
Coiled-coil regions were among the first protein motifs described structurally and theoretically. The simplicity of the motif promises that coiled-coil regions can be detected with reasonable accuracy and precision in any protein sequence.
Dominic Simm   +3 more
doaj   +1 more source

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