Results 11 to 20 of about 297,493 (288)
Spinal muscular atrophy patient iPSC-derived motor neurons have reduced expression of proteins important in neuronal development [PDF]
Frontiers in Cellular Neuroscience, 2016 Spinal muscular atrophy (SMA) is an inherited neuromuscular disease primarily characterized by degeneration of spinal motor neurons, and caused by reduced levels of the SMN protein. Previous studies to understand the proteomic consequences of reduced SMN
Heidi R Fuller +12 more
doaj +2 more sources
Motor proteins at the mitochondria-cytoskeleton interface.
J Cell Sci, 2021 Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways.
Kruppa AJ, Buss F.
europepmc +2 more sources
Critical assessment of coiled-coil predictions based on protein structure data
Scientific Reports, 2021 Coiled-coil regions were among the first protein motifs described structurally and theoretically. The simplicity of the motif promises that coiled-coil regions can be detected with reasonable accuracy and precision in any protein sequence.
Dominic Simm +3 more
doaj +1 more source
Molecular Motors–Nature’s Efficiency at Work
Reports in Advances of Physical Sciences, 2022 Nature has generated sophisticated and very efficient molecular motors, employed for nanoscale transport at the intracellular level. As a complementary tool to nanofluidics, these motors have been envisioned for nanotechnological devices.
Winfried Teizer
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What is axoplasmic transport? Considering the role of exercise training: A mini review [PDF]
Journal of Exercise & Organ Cross Talk, 2022 Like other cells in the body, nerve cells need many proteins and substances to maintain homeostasis. As we know, the transcription and translation of proteins and necessary cellular substances occurs in the cell nucleus.
Hasti Sherizadeh
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Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami
eLife, 2022 Bending of cilia and flagella occurs when axonemal dynein molecules on one side of the axoneme produce force and move toward the microtubule (MT) minus end.
Shimaa A Abdellatef +10 more
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Micron-scale geometrical features of microtubules as regulators of microtubule organization
eLife, 2021 The organization of micron-sized, multi-microtubule arrays from individual microtubules is essential for diverse cellular functions. The microtubule polymer is largely viewed as a passive building block during the organization process.
Nandini Mani +2 more
doaj +1 more source
Regeneration of Assembled, Molecular-Motor-Based Bionanodevices
, 2019 The guided gliding of cytoskeletal filaments, driven by biomolecular motors on nano/microstructured chips, enables novel applications in biosensing and biocomputation. However, expensive and time-consuming chip production hampers the developments.
Cordula Reuther (2524918) +8 more
core +9 more sources
Frontiers in Cell and Developmental Biology, 2022 Tunnelling nanotubes (TNTs) are membranous connections that represent a unique type of intercellular communication in different cell types. They are associated with cell physiology and cancer pathology.
Nataša Resnik +7 more
doaj +1 more source
Mechanisms of Regulation in Intraflagellar Transport
Cells, 2022 Cilia are eukaryotic organelles essential for movement, signaling or sensing. Primary cilia act as antennae to sense a cell’s environment and are involved in a wide range of signaling pathways essential for development. Motile cilia drive cell locomotion
Wouter Mul +2 more
doaj +1 more source