Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. [PDF]
Aging Cell, 2018 Inability to preserve proteostasis with age contributes to the gradual loss of function that characterizes old organisms. Defective autophagy, a component of the proteostasis network for delivery and degradation of intracellular materials in lysosomes ...
Bejarano E +8 more
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Run-and-pause dynamics of cytoskeletal motor proteins. [PDF]
Sci Rep, 2016 Cytoskeletal motor proteins are involved in major intracellular transport processes which are vital for maintaining appropriate cellular function. When attached to cytoskeletal filaments, the motor exhibits distinct states of motility: active motion ...
Hafner AE +3 more
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Sensing surface mechanical deformation using active probes driven by motor proteins. [PDF]
Nat Commun, 2016 Studying mechanical deformation at the surface of soft materials has been challenging due to the difficulty in separating surface deformation from the bulk elasticity of the materials. Here, we introduce a new approach for studying the surface mechanical
Inoue D +6 more
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The role of motor proteins in endosomal sorting [PDF]
Biochemical Society Transactions, 2011 Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie, Stephens, DJ
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Life without double-headed non-muscle myosin II motor proteins
Frontiers in Chemistry, 2014 Non-muscle myosin II motor proteins (myosin IIA, myosin IIB, and myosin IIC) belong to a class of molecular motor proteins that are known to transduce cellular free-energy into biological work more efficiently than man-made combustion engines. Nature has
Venkaiah eBetapudi
doaj +2 more sources
Functions and regulation of the multitasking FANCM family of DNA motor proteins. [PDF]
Genes Dev, 2015 Members of the conserved FANCM family of DNA motor proteins play key roles in genome maintenance processes. In this review, Xue et al. provide an integrated view of the functions and regulation of these enzymes in humans and model organisms and how they ...
Xue X, Sung P, Zhao X.
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Competition between microtubule-associated proteins directs motor transport
Nature Communications, 2018 Motor and non-motor microtubule-associated proteins (MAPs) bind to the microtubule lattice, but it is unclear how their binding activities are coordinated and how this impacts motor transport.
Brigette Y. Monroy +5 more
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Navigation Strategies of Motor Proteins on Decorated Tracks. [PDF]
PLoS ONE, 2015 Motor proteins display widely different stepping patterns as they move on microtubule tracks, from the deterministic linear or helical motion performed by the protein kinesin to the uncoordinated random steps made by dynein.
Zsolt Bertalan +3 more
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Japan-US symposium on cytoskeletal motor proteins and their associated proteins [PDF]
Biophysics and Physicobiology, 2021 Kumiko Hayashi, Shinsuke Niwa
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Molecular switch-like regulation in motor proteins. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2018 Tafoya S, Bustamante C.
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